supported by the Priority Research Program of the Ministry of Science and Technology of the People’s Republic of China(Grant Nos.2017YFA0504600);the National Natural Science Foundation of the People’s Republic of China(Grants Nos.91649103,32091159).
One of the basic questions in the aging field is whether there is a fundamental difference between the aging of lower invertebrates and mammals.A major difference between the lower invertebrates and mammals is the abu...
Objectives: This study aimed to evaluate the prolonged therapeutic effects of a 35 kDa molecular weight hyaluronan fragment (HA35) in alleviating pain associated with myofascial pain syndrome (MPS). Hyaluronan interac...
Transvaginal oocyte retrieval (TVOR) is a common yet painful procedure in assisted reproductive technologies (ART) like in vitro fertilization (IVF). Effective pain management during and after TVOR is essential, parti...
Objective: Few studies have evaluated the effect of oral sodium hyaluronate (SH) ingestion on the moisture content of the superficial stratum corneum. This study aimed to assess whether oral SH ingestion improves the ...
supported by the Guangdong Basic and Applied Basic Research Foundation(2021A1515220120);the Natural Science Foundation of China(grant no.52075285).
Adipose mesenchymal stem cell(ADMSC)-derived exosomes(ADMSC-Exos)have shown great potential in regenerative medicine and been evidenced benefiting wound repair such as burns.However,the low yield,easy loss after direc...
support from the Ministry of Science and ICT of Korea(NRF-2021R1A2C2008821 and 2022H1D3A2A02093385);the Korean Fund for Regenerative Medicine(KFRM)grant funded by the Korean government(21A0301L1-21);The Institute of Engineering Research at Seoul National University provided research facilities,and additional support came from the SNU Engineering-Medicine Collaboration grant.
Wounds, characterized by the disruption of the continuity of body tissues resulting from external trauma,manifest in diverse types and locations. Although numerous wound dressings are available for various woundscenar...
supported by the Key Technologies Research and Development Program[2021YFC2103100];the Key Technology and Development Program of Shandong Province[2022SFGC0103];funded by Shandong Excellent Young Scientists(Overseas)Fund Program[2023HWYQ-002];Taishan Scholars Program[TSQN202312003];the Qilu Young Scholar Fund of Shandong University.
Hyaluronan(HA)is a naturally occurring polysaccharide in the organism.As one of the main components of the extracellular matrix,it plays an important role in regulating various cellular processes,including proliferati...
financially supported by the National Key Research and Development Program of China(No.2021YFC2100900);the National Natural Science Foundation of China(No.32171261);the Taishan Industry Leading Talent of Shandong Province(No.tscx202211017);the Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.KYCX23_2575).
Hyaluronan(HA),a natural high molecular weight polysaccharide,has extensive applications in cosmetology and medical treatment.Hyaluronan-degrading enzymes(Hyals)act as molecular scissors that cleave HA by breaking the...
supported by the National Natural Science Foundation of China(32000058);the Jiangsu Province Natural Science Fund for Distinguished Young Scholars(BK20200025);the National Key Research and Development Program of China(2021YFC2103100).
Leech hyaluronidase(LHyal)is a hyperactive hyaluronic acid(HA)hydrolase that belongs to the hyaluronoglu-curonidase family.Traditionally,LHyal is extracted from the heads of leeches,but the recent development of the P...
Hyaluronic acid (HA) preparations have emerged as pivotal components in contemporary dentistry, gaining widespread recognition for their multifaceted roles in various biological functions. Extensive literature undersc...