INDUCIBLE

作品数:242被引量:997H指数:15
导出分析报告
相关领域:医药卫生更多>>
相关作者:彭向雷林忠平张劲松何锶洁田爱国更多>>
相关机构:北京大学中国科学院遗传与发育生物学研究所南华大学浙江大学医学院附属第一医院更多>>
相关期刊:更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划广东省自然科学基金更多>>
-

检索结果分析

结果分析中...
条 记 录,以下是1-10
视图:
排序:
Plasma extracellular cold inducible RNA-binding protein levels are elevated for 1 month post-colectomy which may promote metastases
《World Journal of Gastrointestinal Oncology》2025年第4期318-326,共9页H M C Shantha Kumara Poppy Addison Xiao-Hong Yan Anuj Raj Sharma Neil Mitra Hansani N Angammana Yanni Hedjar Yi-Ru Chen Vesna Cekic Whelan L Richard 
BACKGROUND Cold-inducible RNA-binding protein(CIRP)is related to a family of stressinduced RNA-binding proteins.It is primarily found in the nucleus,where it regulates transcription.Under stress,CIRP translocates to t...
关键词:Effects of surgery Plasma extracellular cold-inducible RNA-binding protein levels Colorectal resection Colorectal cancer Angiogenesis 
ZIF-90-loaded DNAzyme-responsive PROTAC for the self-powered degradation of NF-κB
《Science China Chemistry》2025年第2期687-693,共7页Min Hou Liang Sun Tianyu Ren Mingda Li Chao Hu Rong Liu Shuang Gu Mingyan Jiang Jian-Hui Jiang Jianjun He 
supported by the National Natural Science Foundation of China(NSFC)Programs(22204046);the Hunan Science Fund for Excellent Young Scholars(2023JJ20002);the National Key Research Program(2019YFA0905800);the Changsha Municipal Natural Science Foundation(kq2402088);the Scientific Research Fund of Hunan Provincial Education Department(22B0874,23B0844).
Transcription factors(TFs)play vital roles in regulating gene expressions.Dysregulated or mutated TFs are implicated in a wide array of diseases,highlighting their potential as drug targets.However,TFs are considered ...
关键词:inducible proteolysis DNAZYME transcription factor ZIF-90 NF-ΚB 
Inducible Fgf13 ablation alleviates cardiac fibrosis via regulation of microtubule stability
《Acta Biochimica et Biophysica Sinica》2024年第12期1802-1812,共11页Cong Wang Xiangchong Wang Yiyi Zhang Yuan Mi Yanxue Han Yaxin Zhi Ran Zhao Nanqi Cui Qianli Ma Huaxing Zhang Dazhong Xue Ruoyang Qiao Jiabing Han Yulou Yu Jiaxuan Li Mohammed Shaiea Demin Liu Guoqiang Gu Chuan Wang 
supported by the grants from the National Natural Science Foundation of China(Nos.81770407 and 31171097);the Key Project of Precision Medicine Joint Fund of Natural Science Foundation of Hebei Province(No.H2020206409);the College Students Innovative Pilot Project in Hebei Medical University(No.USIP2023011);the Science Fund for Creative Research Groups of Natural Science Foundation of Hebei Province(No.H2020206474).
Fibroblast growth factor(FGF)isoform 13,a distinct type of FGF,boasts significant potential for therapeutic intervention in cardiovascular dysfunctions.However,its impact on regulating fibrosis remains unexplored.This...
关键词:FGF13 cardiac fibrosis FIBROBLASTS MICROTUBULE ROCK 
Versatile plant genome engineering using anti-CRISPR-Cas12a systems
《Science China(Life Sciences)》2024年第12期2730-2745,共16页Yao He Shishi Liu Long Chen Dongkai Pu Zhaohui Zhong Tang Xu Qiurong Ren Chuan Dong Yawei Wang Danning Wang Xuelian Zheng Fengbiao Guo Tao Zhang Yiping Qi Yong Zhang 
supported by the Biological Breeding-Major Projects (2023ZD04074);National Natural Science Foundation of China (32270433,32101205 and 32072045);Natural Science Foundation of Sichuan Province (2022NSFSC0143);supported by the NSF Plant Genome Research Program (IOS-2029889 and IOS-2132693)。
CRISPR-Cas12a genome engineering systems have been widely used in plant research and crop breeding.To date,the performance and use of anti-CRISPR-Cas12a systems have not been fully established in plants.Here,we conduc...
关键词:anti-CRISPR Cas12a Acr VA1 off-target effects fine-tuning genome editing inducible and tissue specific genome editing CRISPRa synthetic logic circuit 
PARP7 and nucleic acid-driven oncosuppression
《Cellular & Molecular Immunology》2024年第11期1177-1179,共3页Flavie Naulin Emma Guilbaud Lorenzo Galluzzi 
supported(as a PI,unless otherwise indicated)by one NIH R01 grant(#CA271915);by two Breakthrough Level 2 grants from the US DoD BCRP(#BC180476P1,#BC210945);by a grant from the STARR Cancer Consortium(#I16-0064);by a Transformative Breast Cancer Consortium Grant from the US DoD BCRP(#W81XWH2120034,PI:Formenti);by a U54 grant from NIH/NCI(#CA274291,PIs:Deasy,Formenti,Weichselbaum);by the 2019 Laura Ziskin Prize in Translational Research(#ZP-6177,PI:Formenti)from the Stand Up to Cancer(SU2C)Foundation;by a Mantle Cell Lymphoma Research Initiative(MCL-RI,PI:Chen-Kiang)grant from the Leukemia and Lymphoma Society(LLS);by a Rapid Response Grant from the Functional Genomics Initiative(New York,US);by a pre-SPORE grant(PIs:Demaria,Formenti);a Collaborative Research Initiative Grant and a Clinical Trials Innovation Grant from the Sandra and Edward Meyer Cancer Center(New York,US);by startup funds from the Dept.of Radiation Oncology at Weill Cornell Medicine(New York,US);by industrial collaborations with Lytix Biopharma(Oslo,Norway),Promontory(New York,US)and Onxeo(Paris,France);by donations from Promontory(New York,US);the Luke Heller TECPR2 Foundation(Boston,US),Sotio a.s.(Prague,Czech Republic);Lytix Biopharma(Oslo,Norway);Onxeo(Paris,France);Ricerchiamo(Brescia,Italy);Noxopharm(Chatswood,Australia).
TCDD-inducible poly(ADP-ribose)polymerase(TIPARP,best known as PARP7)has previously been shown to promote oncogenesis by limiting the cytosolic accumulation of potentially interferogenic nucleic acids in malignant cel...
关键词:INDUCIBLE PARP MONO 
Retraction:MicroRNA-374a promotes hepatocellular carcinoma cell proliferation by targeting mitogen-inducible gene 6(MIG-6)
《Oncology Research》2024年第11期1827-1827,共1页Oncology Research Editorial Office 
Following the publication,concerns have been raised about a number of figures in this article.The western blots in this article were presented with atypical,unusually shaped and possibly anomalous protein bands in man...
关键词:raised concerned shaped 
Combination of anti-inflammatory therapy and RNA interference by light-inducible hybrid nanomedicine for osteoarthritis treatment
《Acta Pharmaceutica Sinica B》2024年第11期5008-5025,共18页Li Qiao Zhiyao Li Bowen Li Fu Zhang Zhuo Yao Chongzhi Wu Honglin Tang Qi Pan Peihua Shi Yuan Ping 
National Natural Science Foundation of China(82172458,82371589,82073779,and 32000992);Natural Science Foundation of Zhejiang Province(Distinguished Young Scholar Program,No.LR21H300002,China).
Osteoarthritis(OA)is a type of highly prevalent heterogeneous degenerative disease that leads to joint pain,deformity,the destruction of articular cartilage,and eventual disability.The current treatment strategies for...
关键词:OSTEOARTHRITIS Gold nanocages Poly(β-amino-ester) DIACEREIN Pain relief Photothermal effect Phase-change material Combinational therapy 
Understanding mechanisms for differential salinity tissue tolerance between quinoa and spinach:Zooming on ROS-inducible ion channels被引量:1
《The Crop Journal》2024年第5期1357-1368,共12页Mohsin Tanveer Lei Wang Liping Huang Meixue Zhou Zhong-Hua Chen Sergey Shabala 
supported by the Grassland Ecological Restoration and Management Project of General Grassland Station of Xinjiang (XJCYZZ202102)。
Soil salinity is a wo rldwide issue and a major threat to global food security.Salinity tolerance is a complex mechanism that is conferred by numerous molecular,physiological,and biochemical traits.Of critical importa...
关键词:ACCLIMATION Membrane potential ROS signalling Leaf mesophyll Chenopodium quinoa Spinacia oleracea 
Role of IL-2-inducible T-cell kinase in anti-HBV type I interferon expression and anti-HBV activity
《感染控制(英文)》2024年第2期38-45,共8页Mengxin Lin Jiangfu Liu Zhijun Su Yingying Xu Xiuhua He Ruyi Guo 
supported by Quanzhou City Science&Technology Program of China 455(2022NS056);the Science and Technology Department of Fujian Province(No.2024J01121794).
Objective The study aims to investigate the effects of interleukin-2-inducible T-cell kinase(ITK)on hepatitis B virus(HBV)-induced type I interferon(IFN)expression and the antiviral response.Methods Expression of ITK ...
关键词:hepatitis B virus interleukin-2-inducible T-cell kinase type I interferon 
Protective Effect of Naringenin on Acute Myocardial Ischemia-reperfusion Injury in Rats
《Medicinal Plant》2024年第3期50-52,共3页Xia ZHANG Ping ZHOU Juan LI Zhaojun XIANG Qianqian LUO Qing DENG 
[Objectives]To investigate the protective mechanism of naringenin on acute myocardial ischemia-reperfusion injury(AMI-RI)in Sprague-Dawley(SD)rats.[Methods]A total of 32 SD rats with AMI-RI model construction were ran...
关键词:Rat NARINGENIN Acute myocardial ISCHEMIA-REPERFUSION Lipid PEROXIDATION Inducible/endothelial NITRIC oxide SYNTHASE 
检索报告 对象比较 聚类工具 使用帮助 返回顶部