ISCHEMIC

作品数:602被引量:1968H指数:20
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相关领域:医药卫生更多>>
相关作者:王文孙芳玲张丽艾厚喜蒋莹更多>>
相关机构:首都医科大学北京大学上海交通大学附属第六人民医院青岛大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Targeting harmful effects of non-excitatory amino acids as an alternative therapeutic strategy to reduce ischemic damage
《Neural Regeneration Research》2025年第9期2454-2463,共10页Victoria Jiménez Carretero IrisÁlvarez-Merz Jorge Hernández-Campano Sergei A.Kirov Jesús M.Hernández-Guijo 
supported by MICIU(grant number PID2021-128133NB-100/AEI/FEDER10.13039/501100011033 to JMHG);by the National Institutes of Health(grant number R01 NS083858 to SAK);the Intramural Grants Program IGPP00057(to SAK);VIC enjoys a FPU contract from the Comunidad de Madrid(PIPF-2022/SAL-GL-25948)。
The involvement of the excitatory amino acids glutamate and aspartate in ce rebral ischemia and excitotoxicity is well-documented.Nevertheless,the role of non-excitatory amino acids in brain damage following a stroke ...
关键词:cell swelling N-methyl-D-aspartate receptor non-excitatory amino acids STROKE synaptic transmission 
The potential mechanism and clinical application value of remote ischemic conditioning in stroke被引量:1
《Neural Regeneration Research》2025年第6期1613-1627,共15页Yajun Zhu Xiaoguo Li Xingwei Lei Liuyang Tang Daochen Wen Bo Zeng Xiaofeng Zhang Zichao Huang Zongduo Guo 
supported partly by the National Natural Science Foundation of China,No.82071332;the Chongqing Natural Science Foundation Joint Fund for Innovation and Development,No.CSTB2023NSCQ-LZX0041 (both to ZG)。
Some studies have confirmed the neuroprotective effect of remote ischemic conditioning against stroke. Although numerous animal researches have shown that the neuroprotective effect of remote ischemic conditioning may...
关键词:Akt apoptosis autophagy cerebral perfusion cerebral vascular stenosis clinical transformation hemorrhagic stroke ischemic stroke NEUROINFLAMMATION neuroprotection Notch1 PI3K remote ischemic conditioning STROKE 
Remote ischemic conditioning prevents ischemic cerebrovascular events in children with moyamoya disease:a randomized controlled trial
《World Journal of Pediatrics》2024年第9期925-934,共10页Shuang-Feng Huang Jia-Li Xu Chang-Hong Ren Nathan Sim Cong Han Yi-Qin Han Wen-Bo Zhao Yu-Chuan Ding Xun-Ming Ji Si-Jie Li 
supported by the National Natural Science Foundation of China(Nos.82371305,82001257 and 82274401);the National Key R&D Program of China(No.2022YFC2408800);Beijing Natural Science Foundation(No.JQ22020).
Background Moyamoya disease(MMD)is a significant cause of childhood stroke and transient ischemic attacks(TIAs).This study aimed to assess the safety and efficacy of remote ischemic conditioning(RIC)in children with M...
关键词:Asymptomatic moyamoya disease CHILDREN Remote ischemic conditioning STROKE 
The effect of Huanglian Jiedu Decoction on inflammatory factors and oxidative stress in patients with acute ischemic stroke
《Clinical Research Communications》2024年第1期24-28,共5页Zhen-ying Niu Meng-xue Jin 
supported by Youth Project of Basic Research Special Fund of Yunnan Province(no.202301AZ070001-146).
Objective:To study the clinical efficacy of Huanglian Jiedu decoction in treating acute ischemic stroke(AIS)and its effects on inflammatory factors and oxidative stress.Method:A total of 53 patients with AIS were recr...
关键词:Huanglian Jiedu DECOCTION acute ISCHEMIC STROKE INFLAMMATORY factors OXIDATIVE stress 
Regulatory T cells in ischemic stroke被引量:6
《Acta Pharmacologica Sinica》2022年第1期1-9,共9页Hong-yun Wang Jun-rui Ye Li-yuan Cui Shi-feng Chu Nai-hong Chen 
This work was supported by the National Natural Science Foundation of China(81730096,82074044,81873026,81973499,and 81773924);the Natural Science Foundation of Beijing(7192135);the Drug Innovation Major Project(2018ZX09711001-002-007,2018ZX09711001-003-005,and 2018ZX09711001-009-013);the CAMS Innovation Fund for Medical Sciences(CIFMS)(2016-I2 M-1-004).
Recent evidence shows that when ischemic stroke(IS)occurs,the BBB would be destructed,thereby promoting the immune cells to migrate into the brain,suggesting that the immune responses can play a vital role in the path...
关键词:regulatory T cells ischemic stroke INFLAMMATION CROSSTALK stroke-induced immunodepression ischemic stroke therapy 
Interactions between remote ischemic conditioning and post-stroke sleep regulation被引量:6
《Frontiers of Medicine》2021年第6期867-876,共10页Xian Wang Xunming Ji 
supported by the National Key R&D Program of China(No.2017YFC1308401);the Talent Introduction Project of the Beijing Bureau of Foreign Expert(No.BJ2018001).
Sleep disturbances are common in patients with stroke,and sleep quality has a critical role in the onset and outcome of stroke.Poor sleep exacerbates neurological injury,impedes nerve regeneration,and elicits serious ...
关键词:remote ischemic conditioning sleep regulation STROKE 
Risk Factors Affecting Ischemic Stroke: A Potential Side Effect of Antihypertensive Drugs被引量:2
《Health》2020年第5期437-455,共19页Kazumitsu Nawata 
Background: Stroke is a worldwide health problem, the world’s second-leading cause of death and third-leading cause of disability. Currently, the majority of stroke patients are ischemic stroke patients. It is necess...
关键词:STROKE ISCHEMIC STROKE CEREBROVASCULAR History ANTIHYPERTENSIVE Drug Side Effect 
Neuroprotective effects of minocycline on focal cerebral ischemia injury: a systematic review被引量:13
《Neural Regeneration Research》2020年第5期773-782,共10页Yazdan Naderi Yunes Panahi George E. Barreto Amirhosein Sahebkar 
To review the neuroprotective effects of minocycline in focal cerebral ischemia in animal models.By searching in the databases of PubMed,ScienceDirect,and Scopus,and considering the inclusion and exclusion criteria of...
关键词:ISCHEMIC STROKE MINOCYCLINE NEURONAL regeneration NEUROPROTECTION STROKE 
Management of Acute Ischemic Stroke in a Patient with a Past History of Intracranial Hemorrhage被引量:1
《Neuroscience & Medicine》2020年第1期29-35,共7页Ghadeer Al-Shabeeb Fatimah Al Zawad Osama Basheir 
Intravenous thrombolysis remains the gold standard in the management of acute ischemic stroke if the patient presents within the window period. Endovascular thrombectomy is another line of therapy in selected cases. N...
关键词:ISCHEMIC STROKE ACUTE ISCHEMIC STROKE IVtPA in History of HEMORRHAGIC STROKE HEMORRHAGIC STROKE INTRAVENOUS THROMBOLYSIS 
Association between PPARG genetic polymorphisms and ischemic stroke risk in a northern Chinese Han population: a case-control study被引量:15
《Neural Regeneration Research》2019年第11期1986-1993,共8页Yan-Zhe Wang He-Yu Zhang Fang Liu Lei Li Shu-Min Deng Zhi-Yi He 
supported by the National Natural Science Foundation of China,No.81070913(to ZYH)
Two common polymorphisms of the peroxisome proliferator-activated receptor gamma(PPARG) gene, rs1801282 and rs3856806, may be important candidate gene loci affecting the susceptibility to ischemic stroke. This case-co...
关键词:nerve REGENERATION STROKE cerebral ischemia ISCHEMIC STROKE PEROXISOME proliferator-activated receptor γ single-nucleotide polymorphism haplotype analysis interaction CASE-CONTROL study Chinese Han population neural REGENERATION 
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