supported by MICIU(grant number PID2021-128133NB-100/AEI/FEDER10.13039/501100011033 to JMHG);by the National Institutes of Health(grant number R01 NS083858 to SAK);the Intramural Grants Program IGPP00057(to SAK);VIC enjoys a FPU contract from the Comunidad de Madrid(PIPF-2022/SAL-GL-25948)。
The involvement of the excitatory amino acids glutamate and aspartate in ce rebral ischemia and excitotoxicity is well-documented.Nevertheless,the role of non-excitatory amino acids in brain damage following a stroke ...
supported partly by the National Natural Science Foundation of China,No.82071332;the Chongqing Natural Science Foundation Joint Fund for Innovation and Development,No.CSTB2023NSCQ-LZX0041 (both to ZG)。
Some studies have confirmed the neuroprotective effect of remote ischemic conditioning against stroke. Although numerous animal researches have shown that the neuroprotective effect of remote ischemic conditioning may...
supported by the National Natural Science Foundation of China(Nos.82371305,82001257 and 82274401);the National Key R&D Program of China(No.2022YFC2408800);Beijing Natural Science Foundation(No.JQ22020).
Background Moyamoya disease(MMD)is a significant cause of childhood stroke and transient ischemic attacks(TIAs).This study aimed to assess the safety and efficacy of remote ischemic conditioning(RIC)in children with M...
supported by Youth Project of Basic Research Special Fund of Yunnan Province(no.202301AZ070001-146).
Objective:To study the clinical efficacy of Huanglian Jiedu decoction in treating acute ischemic stroke(AIS)and its effects on inflammatory factors and oxidative stress.Method:A total of 53 patients with AIS were recr...
This work was supported by the National Natural Science Foundation of China(81730096,82074044,81873026,81973499,and 81773924);the Natural Science Foundation of Beijing(7192135);the Drug Innovation Major Project(2018ZX09711001-002-007,2018ZX09711001-003-005,and 2018ZX09711001-009-013);the CAMS Innovation Fund for Medical Sciences(CIFMS)(2016-I2 M-1-004).
Recent evidence shows that when ischemic stroke(IS)occurs,the BBB would be destructed,thereby promoting the immune cells to migrate into the brain,suggesting that the immune responses can play a vital role in the path...
supported by the National Key R&D Program of China(No.2017YFC1308401);the Talent Introduction Project of the Beijing Bureau of Foreign Expert(No.BJ2018001).
Sleep disturbances are common in patients with stroke,and sleep quality has a critical role in the onset and outcome of stroke.Poor sleep exacerbates neurological injury,impedes nerve regeneration,and elicits serious ...
Background: Stroke is a worldwide health problem, the world’s second-leading cause of death and third-leading cause of disability. Currently, the majority of stroke patients are ischemic stroke patients. It is necess...
To review the neuroprotective effects of minocycline in focal cerebral ischemia in animal models.By searching in the databases of PubMed,ScienceDirect,and Scopus,and considering the inclusion and exclusion criteria of...
Intravenous thrombolysis remains the gold standard in the management of acute ischemic stroke if the patient presents within the window period. Endovascular thrombectomy is another line of therapy in selected cases. N...
supported by the National Natural Science Foundation of China,No.81070913(to ZYH)
Two common polymorphisms of the peroxisome proliferator-activated receptor gamma(PPARG) gene, rs1801282 and rs3856806, may be important candidate gene loci affecting the susceptibility to ischemic stroke. This case-co...