云南高校图书馆联盟文献共享服务平台- MILD

MILD: 作品数：665被引量：1357H指数：16; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：范虹霞周月桂米建春张海张立麒更多>>; 相关机构：华中科技大学兰州交通大学西北师范大学北京大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划国家教育部博士点基金更多>>

HDAC6 inhibitor loaded bimetallene nanosheets with antagonizing thermoresistance for augmented mild photothermal therapy: 《Chinese Chemical Letters》2023年第9期235-242,共8页Lingyu Qiu Shan Lei Jing Zhang Ruhan Yan Wansi Chen Jing Lin Wei-Guo Zhu Peng Huang; financially supported by National Key R&D Program of China(Nos.2020YFA0908800,2018YFA0704000);Basic Research Program of Shenzhen(Nos.JCYJ20200109105620482,JCYJ20180507182413022);Shenzhen Science and Technology Program(No.KQTD20190929172538530)。; Photothermal therapy(PTT)induces thermoresistance through cellular heat shock response,which impairs the therapeutic efficacy of the PTT.To resolve this problem,we developed a photothermal theranostics(denoted as PMH)...; 关键词：Mild photothermal therapy THERMORESISTANCE Histone deacetylase 6 Heat shock proteins AUTOPHAGY

A mild phenoxysilyl linker for self-immolative release of antibody-drug conjugates: 《Chinese Chemical Letters》2023年第5期494-498,共5页Ding Wei Yurong Mao Huihui Wang Siqi Qu Jiakang Chen Jiusheng Li Biao Jiang Hongli Chen; supported by Shanghai Frontiers Science Center for Biomacromolecules and Precision Medicine at Shanghai Tech University。; Self-immolative linkers have been widely used to construct prodrugs to improve their efficacy and safety.In this study,we report the use of phenoxysilyl linker as a self-immolative unit to prepare antibody-drug conjug...; 关键词：Antibody-drug conjugates Self-immolative release Phenoxysilyl linker Combretastatin A4(CA4)

Hydrogen bond-assisted 1,2-cis O-glycosylation under mild hydrogenolytic conditions被引量：1: 《Chinese Chemical Letters》2023年第4期313-317,共5页Gefei Li Yanlong Luo Juan Mo Masato Noguchi Jie Jing Zhenyang Luo Shin-ichiro Shoda Xin-Shan Ye; financially supported by the State Key Laboratory of Natural and Biomimetic Drugs (No. K202216);the National Natural Science Foundation of China (Nos. 21907004 and 81821004);the National Key R&D Program of China (No.2018YFA0507602);the Beijing Outstanding Young Scientist Program(No. BJJWZYJH01201910001001);a Grant-in-Aid for Scientific Research from the Ministry of Education,Culture,Sports,Science and Technology,Japan。; A hydrogen bond-assisted α-selective glycosylation reaction by using 4,6-dibenzyloxy-1,3,5-triazin-2-yl(DBT) β-glycosyl donors was developed for the efficient construction of 1,2-cis-α-glycosidic bond in natural pr...; 关键词：O-GLYCOSYLATION Hydrogen bond α-Selectivity GLYCOLIPID Natural product

Metal-polyphenol-coordinated nanomedicines for Fe(II) catalyzed photoacoustic-imaging guided mild hyperthermia-assisted ferroustherapy against breast cancer被引量：2: 《Chinese Chemical Letters》2022年第4期1895-1900,共6页Xinying Yu Tongyi Shang Guodong Zheng Hailong Yang Yuwei Li Yanjun Cai Guoxi Xie Bin Yang; supported by grants from the National Natural Science Foundation of China (No. 51903062);Guangdong Basic and Applied Basic Research Foundation (No.2020A1515011320);Science and Technology Projects of Guangzhou(No. 202102020757);Subject Construction Project of Basic Medical Sciences of Guangzhou Medical University (Nos.JCXKJS2021B07, JCXKJS2021D09)。; Ferroustherapy has gained great attention for anti-cancer treatment in recent years. Enlightened by temperature-mediated Fenton reaction in industrial waste water removal, we designed a iron-based polyphenol-coordinat...; 关键词：Ferroptosis Metal-polyphenol nanomedicines Fenton reaction Mild hyperthermia Photoacoustic imaging

Strategies for efficient photothermal therapy at mild temperatures:Progresses and challenges被引量：1: 《Chinese Chemical Letters》2022年第2期575-586,共12页Peng Gao Hui Wang Yiyun Cheng; financially supported by the Guangdong Provincial Key Laboratory of Functional and Intelligent Hybrid Materials and Devices (No.2019B121203003)。; Photothermal therapy(PTT), typically ablates tumors via hyperthermia generated from photothermal agents(PTAs) under laser irradiation, has attracted great attentions in the past decades. Unfortunately,longstanding, fr...; 关键词：Photothermal therapy Mild hyperthermia Photothermal agents NANOMEDICINE Tumor targeted therapy

Mild hyperthermia-enhanced chemo-photothermal synergistic therapy using doxorubicin-loaded gold nanovesicles被引量：1: 《Chinese Chemical Letters》2021年第8期2411-2414,共4页Zhuoting Deng Chao Jiang Muhammad Rizwan Younis Shan Lei Yaling He Haoxing Zheng Peng Huang Jing Lin; financially supported by the National Natural Science Foundation of China (Nos.31771036,51703132);the Basic Research Program of Shenzhen (Nos.JCYJ20180507182413022,JCYJ20170412111100742);the Guangdong Province Natural Science Foundation of Major Basic Research and Cultivation Project (No.2018B030308003)。; Gold nanovesicles(GVs) with unique plasmonic property and large cavity hold great potential as a stimuli-responsive nanocarrier to deliver drugs for efficient tumor chemotherapy and other therapies synergistically.Her...; 关键词：Mild hyperthermia Chemo-photothermal synergistic therapy Gold nanovesicles DOXORUBICIN Photoacoustic imaging

Visible light induced cross-coupling synthesis of asymmetrical heterobiaryls using Pd/CeO_2 nanocomposite photocatalyst: 《Chinese Chemical Letters》2018年第6期903-906,共4页Yanqin Ge Pinhui Diao Chen Xu Nannan Zhang Cheng Guo; A simple, mild and green approach has been developed for the synthesis of asymmetrical heterobiaryls under the irradiation of visible light without any oxidants and promoting reagents through using Pd/Ce O2 nanocompos...; 关键词：Visible light Nanocomposite photocatalyst Pd/CeO2 C—C cross-coupling Mild condition

Hydrogenation of cinnamaldehyde over bimetallic Au-Cu/CeO_2 catalyst under a mild condition被引量：2: 《Chinese Chemical Letters》2017年第2期293-296,共4页Xue-Mei Liao Veronique Pitchon Pham-Huu Cuong Wei Chu Valerie Caps; the Chinese Scholarship Council (CSC), French Eiffel Scholarship for financial supports of Xuemei Liao;the financial supported by the Open Research Subject of key laboratory (Research Base) of Grain and Oil Engineering and food safety (No. szjj2015-006);Agricultural and Forestry Talents in Food quality and safety, Key Research Fund of Xihua University (No. Z1520527); Bimetallic Au_xCu_y/CeO_2（x/y = 3/1,1/1,and 1 /3） catalysts were prepared by direct anion exchange（DAE）,following impregnation（IMP） methods,and used for selective hydrogenation of cinnamaldehyde.The effects of p...; 关键词：Hydrogenation of cinnamaldehyde Bimetallic Au-Cu catalysts Reduction or calcination Distribution Alloy

Rapid and mild synthesis of quinazolinones and chromeno[d]pyrimidinones using nanocrystalline copper(Ⅰ)iodide under solvent-free conditions: 《Chinese Chemical Letters》2016年第1期114-118,共5页Shahrzad Abdolmohammadi Samira Karimpour; the financial support from the Research Council of East Tehran Branch, Islamic Azad University; This paper describes a very simple, efficient synthesis of quinazolinones and chromeno[d]pyrimidinones from the reaction of aryl aldehydes, urea/thiourea and active methylene compounds（dimedone/4-hydroxycoumarin） us...; 关键词：Chromeno[d]pyrimidinones Copper（Ⅰ） iodide nanoparticles QUINAZOLINONES Solvent-free conditions

Efficient and mild cyclization procedures for the synthesis of novel 2-amino-4H-pyran derivatives with potential antitumor activity被引量：2: 《Chinese Chemical Letters》2014年第7期1011-1013,共3页Dao-Cai Wang Yong-Mei Xie Chen Fan Shun Yao Hang Song; A series of novel 2-amino-4H-pyran derivatives have been synthesized via a three-component reaction of α,β-unsaturated ketone derivatives, malononitrile, aldehydes in excellent yields, using DBU as a catalyst and et...; 关键词：Synthesis 2-Amino-4H-pyran derivatives MULTICOMPONENT ANTICANCER

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