云南高校图书馆联盟文献共享服务平台- MITOCHONDRIAL

MITOCHONDRIAL: 作品数：880被引量：2426H指数：17; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：戴朴王朝霞侯婷婷管敏鑫唐霄雯更多>>; 相关机构：北京大学中国科学院中国人民解放军总医院中国科学院遗传与发育生物学研究所更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>

Mitochondrial transplantation:a promising strategy for the treatment of retinal degenerative diseases: 《Neural Regeneration Research》2025年第12期3370-3387,共18页Jing Chi Bin Fan Yulin Li Qing Jiao Guang-Yu Li; supported by the National Natural Science Foundation of China,Nos.8247041526,81570864,82171053(to GYL)。; The retina,a crucial neural tissue,is responsible for transforming light signals into visual information,a process that necessitates a significant amount of energy.Mitochondria,the primary powerhouses of the cell,play...; 关键词：age-related macular degeneration Leber’s hereditary optic neuropathy mitochondrial transfer mitochondrial transplantation retinal degenerative diseases

Utilizing engineered extracellular vesicles as delivery vectors in the management of ischemic stroke:a special outlook on mitochondrial delivery: 《Neural Regeneration Research》2025年第8期2181-2198,共18页Jiali Chen Yiyang Li Xingping Quan Jinfen Chen Yan Han Li Yang Manfei Zhou Greta Seng Peng Mok Ruibing Wang Yonghua Zhao; supported by the grants from University of Macao,China,Nos.MYRG2022-00221-ICMS(to YZ)and MYRG-CRG2022-00011-ICMS(to RW);the Natural Science Foundation of Guangdong Province,No.2023A1515010034(to YZ)。; Ischemic stroke is a secondary cause of mortality worldwide,imposing considerable medical and economic burdens on society.Extracellular vesicles,serving as natural nanocarriers for drug delivery,exhibit excellent bioc...; 关键词：delivery engineering extracellular vesicles identification ischemic stroke isolation MITOCHONDRIA targeting strategy therapeutic effects

Mitochondrial therapeutics and mitochondrial transfer for neurodegenerative diseases and aging: 《Neural Regeneration Research》2025年第3期794-796,共3页Neville Ng Michelle Newbery Nicole Miles Lezanne Ooi; supported by a MAWA Project Grant(to NN,MN,LO)。; Mitochondrial dysfunction and neurodegeneration:Progressive neurodegenerative diseases affect a significant proportion of the population;in a single year,there are as many as 276 million disabilities and 9 million dea...; 关键词：DEGENERATIVE DISEASES MITOCHONDRIAL

Mitochondrial recruitment in myelin:an anchor for myelin dynamics and plasticity?: 《Neural Regeneration Research》2024年第7期1401-1402,共2页Jean-David M.Gothié Timothy E.Kennedy; supported by on operating grant(#1038154) from the Multiple Sclerosis Society of Canada (to TEK);a Multiple Sclerosis Society of Canada Post-Doctoral Fellowship (to JDMG)。; Optimal propagation of neuronal electrical impulses depends on the insulation of axons by myelin,produced in the central nervous system by oligodendrocytes.Myelin is an extension of the oligodendrocyte plasma membrane...; 关键词：PLASTICITY insulation DYNAMICS

Post-acute ischemic stroke hyperglycemia aggravates destruction of the blood-brain barrier被引量：2: 《Neural Regeneration Research》2024年第6期1344-1350,共7页Tianqi Xu Jianhong Yang Yao Xu Xiaofeng Wang Xiang Gao Jie Sun Chenhui Zhou Yi Huang; supported by the Ningbo Public Welfare Science and Technology Program,No.2022S023(to JY);Ningbo Natural Science Foundation,No.2022J211(to JS);Ningbo Medical and Health Brand Discipline,No.PPXK2018-04(to XG);Ningbo Top Medical and Health Research Program,No.2022020304(to XG);Key Laboratory of Precision Medicine for Atherosclerotic Diseases of Zhejiang Province,No.2022E10026(to YH)。; Post-acute ischemic stroke hyperglycemia increases the risk of hemorrhagic transformation,which is associated with blood-brain barrier disruption.Brain microvascular endothelial cells are a major component of the bloo...; 关键词：acute ischemic stroke blood-brain barrier brain microvascular endothelial cells mitochondrial transfer stress hyperglycemia

Promising use of metformin in treating neurological disorders:biomarker-guided therapies被引量：2: 《Neural Regeneration Research》2024年第5期1045-1055,共11页Allison Loan Charvi Syal Margarita Lui Ling He Jing Wang; Neurological disorders are a diverse group of conditions that affect the nervous system and include neurodegenerative diseases(Alzheimer’s disease,multiple sclerosis,Parkinson’s disease,Huntington’s disease),cerebr...; 关键词：Alzheimer’s disease Huntington’s disease METFORMIN mitochondrial perturbation multiple sclerosis neural degenerative diseases Parkinson’s disease stroke targeted therapy

Mitochondrial dysfunction and quality control lie at the heart of subarachnoid hemorrhage被引量：5: 《Neural Regeneration Research》2024年第4期825-832,共8页Jiatong Zhang Qi Zhu Jie Wang Zheng Peng Zong Zhuang Chunhua Hang Wei Li; supported by the National Natural Science Foundation of China,Nos.82130037(to CH),81971122(to CH),82171323(to WL);the Natural Science Foundation of Jiangsu Province of China,No.BK20201113(to WL)。; The dramatic increase in intracranial pressure after subarachnoid hemorrhage leads to a decrease in cerebral perfusion pressure and a reduction in cerebral blood flow.Mitochondria are directly affected by direct facto...; 关键词：mitochondrial biogenesis mitochondrial dynamics mitochondrial dysfunction mitochondrial fission and fusion mitochondrial quality control MITOPHAGY subarachnoid hemorrhage

Latest assessment methods for mitochondrial homeostasis in cognitive diseases被引量：3: 《Neural Regeneration Research》2024年第4期754-768,共15页Wei You Yue Li Kaixi Liu Xinning Mi Yitong Li Xiangyang Guo Zhengqian Li; supported by the National Natural Science Foundation of China,Nos.82271222(to ZL),81971012(to ZL),82071189(to XG),and 82201335(to YL);Key Clinical Projects of Peking University Third Hospital,No.BYSYZD2019027(to ZL)。; Mitochondria play an essential role in neural function,such as supporting normal energy metabolism,regulating reactive oxygen species,buffering physiological calcium loads,and maintaining the balance of morphology,sub...; 关键词：cognitive disorders mitochondrial dysfunction mitochondrial energy metabolism mitochondrial dynamics mitochondrial transport MITOPHAGY mitochondrial biogenesis oxidative stress calcium homeostasis

Mitochondrial DNA methylation and mitochondria-related epigenetics in neurodegeneration被引量：4: 《Neural Regeneration Research》2024年第2期405-406,共2页Fabio Coppedè; Mitochondria are cytoplasmic organelles referred to as the powerhouse of the cell because they are primarily involved in oxidative phosphorylation and energy production.They are particularly abundant in tissues with h...; 关键词：IMPAIRED NEURODEGENERATION oxidative

Mitochondria in Huntington’s disease:implications in pathogenesis and mitochondrial-targeted therapeutic strategies被引量：1: 《Neural Regeneration Research》2023年第7期1472-1477,共6页Anamaria Jurcau Carolina Maria Jurcau; Huntington’s disease is a genetic disease caused by expanded CAG repeats on exon 1 of the huntingtin gene located on chromosome 4.Compelling evidence implicates impaired mitochondrial energetics,altered mitochondrial...; 关键词：ANTIOXIDANTS calcium homeostasis Huntington’s disease mitochondrial biogenesis mitochondrial fission/fusion mitochondrial trafficking oxidative phosphorylation oxidative stress SS peptides therapeutic intervention

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