《Journal of Clinical and Translational Hepatology》

作品数：890被引量：3035H指数：22
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《Journal of Clinical and Translational Hepatology》
主办单位：重庆医科大学第二附属医院
最新期次：2024年12期更多>>
发文主题：HEPATOCELLULAR_CARCINOMACIRRHOSISLIVERHEPATITIS_B_VIRUSLIVER_FIBROSIS更多>>
发文领域：医药卫生经济管理文化科学环境科学与工程更多>>
发文基金：国家自然科学基金中国博士后科学基金广东省自然科学基金广西壮族自治区自然科学基金更多>>
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Advanced Liver Fibrosis Predicts Liver Outcomes in Biopsyproven Metabolic Dysfunction-associated Steatotic Liver Disease: A U.S.-based Single-center Retrospective Cohort Study
《Journal of Clinical and Translational Hepatology》2024年第12期988-996,共9页Robert Lam Dhanpat Jain Yanhong Deng Eesha Acharya Joseph K.Lim 
Background and Aims:Data regarding risk factors and long-term outcomes of U.S.patients with biopsy-proven metabolic dysfunction-associated steatotic liver disease(MASLD)are limited.This study aimed to investigate the ...
关键词：Liver fibrosis Metabolic dysfunction-associated steatotic liver disease Liver decompensation Liver event Long-term outcomes Risk factor Histology. 
Anti-hepatitis B Virus Treatment with Tenofovir Amibufenamide Has No Impact on Blood Lipids: A Real-world, Prospective, 48-week Follow-up Study
《Journal of Clinical and Translational Hepatology》2024年第12期997-1008,共12页Yue Chen Wenkang Gao Huikuan Chu Afnan Ahmed Mohamed Al-Asbahi Shengqi Yan Hang Yuan Jiake Che Zilu Cheng Zexuan Li Jin Ye Rong Lin Xiaohua Hou Fan Du Ling Yang 
funded by the National Natural Science Foundation of China[82270614,81974078,81570530,and 81370550 to LY,82000561to HC];the National Key R&D Program of China[2023YFC2413804 to LY and 2022YFA1305600 to HC];the Science Foundation of Hubei Province[2019ACA133 to LY]and the Science Foundation of Union Hospital[2021xhyn005]to HC.
Background and Aims:The effect of tenofovir amibufenamide(TMF)on blood lipid profiles in patients with chronic hepatitis B(CHB)remains unclear.This study aimed to explore whether TMF affects blood lipids during 48 wee...
关键词：Tenofovir amibufenamide Antiviral treatment Chronic hepatitis B Blood lipid Virological response Palmitic acid 
The Imbalance of Homeostasis in Neutrophil Extracellular Traps is Associated with Portal Vein Thrombosis in Patients with Decompensated Cirrhosis
《Journal of Clinical and Translational Hepatology》2024年第12期1009-1019,共11页Ming Han Yujia Liu Ying Cao Yue Zhang Yonghong Yan Shuwei Deng Xiaoxue Yuan Huichun Xing Yuan Huang Liuluan Zhu 
supported by the Beijing High-Level Public Health Technical Talent Training Program(discipline backbone talent-02-32),the National Natural Science Foundation of China(No.81871586),and the Beijing Municipal Administration of Hospitals Incubating Program(PX2021066).
Background and Aims:Portal vein thrombosis(PVT)is a challenging complication in liver cirrhosis,with no currently available sensitive diagnostic markers.This study aimed to investigate the potential of neutrophil extr...
关键词：Portal vein thrombosis Neutrophil extracellular trap DEOXYRIBONUCLEASE Chronic hepatitis B Decompensated cirrhosis Hepatocellular carcinoma. 
Exploring Circulating Tumor Cells: Detection Methods and Biomarkers for Clinical Evaluation in Hepatocellular Carcinoma
《Journal of Clinical and Translational Hepatology》2024年第12期1020-1042,共23页Chin-Mu Hsu Yi-Chang Liu Jee-Fu Huang 
supported in part by grants from the Ministry of Science and Technology,Taiwan(MOST 107-2314-B-037-082-MY3 to JFH,110-2314-B-03-073-MY3 to JFH);the National Science and Technology Council,Taiwan(NSTC112-2314-B-037-072 to YCL);the National Yang Ming Chiao Tung University-Kaohsiung Medical University Joint Research Project(NYCU-KMU-111-I001 to JFH,NYCU-KMU-112-I001 to JFH);and Kaohsiung Medical University Hospital(KMUH110-0R05 to JFH,KMUH110-0R20 to YCL,KMUH111-1M16 to YCL,KMUH111-1M17 to CMH,KMUH111-1R06 to JFH,KMUH SH11208 to YCL,KMUH-DK(B)110001-3 to YCL,KMUH-DK109006-2 to YCL).
Circulating tumor cells(CTCs),originating from primary neoplastic tissues,infiltrate blood vessels,migrate through the bloodstream,and establish secondary tumor foci.The detection of CTCs holds significant promise for...
关键词：Circulating tumor cells CTC Hepatocellular carcinoma HCC Clinical application CTC enrichment BIOMARKER PROGRESSION Microvascular invasion MVI ALPHA-FETOPROTEIN AFP. 
Emerging Roles of High-mobility Group Box-1 in Liver Disease
《Journal of Clinical and Translational Hepatology》2024年第12期1043-1056,共14页Lu Wang Zhiwei Dong Yeqiong Zhang Liang Peng 
supported by grants from the Natural Science Foundation of China(82070611);the Guangzhou Science and Technology Plan Projects(2023B03J1287);the Guangdong Medical Science and Technology Research Fund(A2021304);the Five-Year Plan of the Third Affiliated Hospital of Sun Yat-sen University(2024W106);the Shandong Provincial Natural Science Foundation(ZR2024QH660).
High-mobility group box-1(HMGB1)is an architectural chromosomal protein with various roles depending on its cellular localization.Extracellular HMGB1 functions as a prototypical damage-associated molecular pattern tha...
关键词：High-mobility group box-1 Liver disease Damage-associated molecular pattern PATHOGENESIS Signaling pathway Post-translational modifications. 
Ferroptosis and Intrinsic Drug-induced Liver Injury by Acetaminophen and Other Drugs: A Critical Evaluation and Historical Perspective
《Journal of Clinical and Translational Hepatology》2024年第12期1057-1066,共10页Hartmut Jaeschke Anup Ramachandran 
supported in part by National Institute of Diabetes and Digestive and Kidney Diseases grants R01 DK102142(HJ)and R01 DK125465(AR),as well as by National Institute of General Medical Sciencesfunded Liver Disease COBRE grants P20 GM103549(HJ)and P30 GM118247(HJ).
Drug-induced hepatotoxicity is a significant clinical issue worldwide.Given the limited treatment options for these liver injuries,understanding the mechanisms and modes of cell death is crucial for identifying novel ...
关键词：Drug hepatotoxicity ACETAMINOPHEN Lipid peroxidation Oxidative stress Ferroptosis Glutathione peroxidase 4 Erastin Ferrostatin-1 METHOTREXATE RIFAMPICIN ISONIAZID Natural products 
The Failure Rate of Liver Stiffness Measured by Vibrationcontrolled Transient Elastography in the United States and Relevant Factors
《Journal of Clinical and Translational Hepatology》2024年第12期1067-1069,共3页Ruoqi Zhou Jiyang Chen Rui Huang Yida Yang Yu Shi 
supported by the National Key Research and Development Program of China(No.2022YFC2304501 and No.2021YFC2301800);the Fundamental Research Funds for the Central Universities(2023QZJH50);the Medical Health Science and Technology Project of the Zhejiang Provincial Health Commission(No.2022RC141);the Chinese National Natural Science Foundation(No.81870425).
Citation of this article:Zhou R,Chen J,Huang R,Yang Y,Shi Y.The Failure Rate of Liver Stiffness Measured by Vibrationcontrolled Transient Elastography in the United States and Relevant Factors.J Clin Transl Hepatol 20...
关键词：LIVER CIRRHOSIS Vibration 
2024 Reviewer Acknowledgement
《Journal of Clinical and Translational Hepatology》2024年第12期1070-1073,共4页
Prolonged Direct Hyperbilirubinemia Following Acute Hepatitis: When Not to Worry?
《Journal of Clinical and Translational Hepatology》2024年第12期985-987,F0003,共4页Danzhu Zhao George Y.Wu 
Introduction Serum direct bilirubin levels,consisting mostly of conjugated bilirubin,are often elevated in acute hepatitis due to cholestasis.This usually results in jaundice,which resolves as the hepatitis improves.H...
关键词：ELEVATED DELTA mostly 
Identification and Validation of the Hsa_circ_0001726/miR-140-3p/KRAS Axis in Hepatocellular Carcinoma Based on Microarray Analyses and Experiments
《Journal of Clinical and Translational Hepatology》2024年第11期897-906,共10页Xiaobin Chi Zhijian Chen Jianda Yu Xiaohua Xie Zerun Lin Yongbiao Chen Lizhi Lv 
supported by the Fujian Natural Science Foundation Project(General)[Grant number:2021J011265];the Fund for Scientific Research Projects of the Organ Transplantation Section of the Joint Logistics Support Force Key Discipline of Joint Logistics Medicine[Grant number:LQZDQG].
Background and Aims:Hepatocellular carcinoma(HCC)is one of the most fatal malignancies.Epigenetic mechanisms have revealed that noncoding RNAs,such as microRNAs(miRNAs)and circular RNAs(circRNAs),are involved in HCC p...
关键词：Circular RNA microRNA PROGNOSIS Hepatocellular cancer BIOINFORMATICS Tyrosine kinase inhibitor 
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