云南高校图书馆联盟文献共享服务平台- Life Metabolism

《Life Metabolism》: 作品数：134被引量：28H指数：2; 导出分析报告; 主办单位：高等教育出版社有限公司; 最新期次：2025年1期更多>>; 发文主题：METABOLISMOBESITYMETABOLICHOMEOSTASISMICE更多>>; 发文领域：医药卫生生物学文化科学农业科学更多>>; 发文基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划北京市自然科学基金更多>>

Editorial Board: 《Life Metabolism》2025年第1期I0001-I0002,共2页

PCSK9 V474I germline variant drives breast cancer metastasis: 《Life Metabolism》2025年第1期1-3,共3页Hai Wang Zhiming Shao; Breast cancer metastasis remains the leading cause of mortality in patients,yet its mechanisms are poorly understood.A recent Cell paper highlights the pivotal role of the proprotein convertase subtilisin/kexin type 9...; 关键词：METASTASIS cancer MORTALITY

Biphasic glucose-stimulated insulin secretion over decades:a journey from measurements and modeling to mechanistic insights: 《Life Metabolism》2025年第1期5-15,共11页Xiaohong Peng Kai Wang Liangyi Chen; the National Center for Protein Sciences at Peking University in Beijing,China;supported by the National Natural Science Foundation of China(81925022,T2288102,and 32227802);the National Key Research and Development Program of China(2022YFC3400600);the Beijing Natural Science Foundation(Z20J00059 and 7244366);the Fundamental Research Funds for the Central Universities(PKU2024XGK011);supported by the New Cornerstone Science Foundation;the High-performance Computing Platform of Peking University.; Glucose-stimulated insulin release from pancreaticβ-cells is critical for maintaining blood glucose homeostasis.An abrupt increase in blood glucose concentration evokes a rapid and transient rise in insulin secretion...; 关键词：glucose-stimulated insulin secretion vesicle pools readily releasableβ-cells β-cell heterogeneity

Glucose-6-phosphate dehydrogenase regulates mitophagy by maintaining PINK1 stability: 《Life Metabolism》2025年第1期17-34,共18页Yik-Lam Cho Hayden Weng Siong Tan Jicheng Yang Basil Zheng Mian Kuah Nicole Si Ying Lim Naiyang Fu Boon-Huat Bay Shuo-Chien Ling Han-Ming Shen; supported by grants to S.C.L.from the Swee Liew-Wadsworth Endowment fund,National University of Singapore(NUS),Ministry of Education(MOE-T2EP30220-0014),Singapore;the National Research Foundation(NRF-ISF003-3221),Singapore;grants to H.M.S.from University of Macao(CPG2023-0032FHS and UM-MYRG2020-00022-FHS);Macao Science and Technology Development Fund(FDCT0078/2020/A2,FDCT0031/2021/A1,FDCT0081/2022/AMJ,and FDCT 0004/2021/AKP);supported by the NUS Graduate School Research Scholarships.; Glucose-6-phosphate dehydrogenase(G6PD)is the rate-limiting enzyme in the pentose phosphate pathway(PPP)in glycolysis.Glucose metabolism is closely implicated in the regulation of mitophagy,a selective form of autopha...; 关键词：G6PD MITOPHAGY PINK1 ROS NADPH PPP

CIDEC/FSP27 exacerbates obesity-related abdominal aortic aneurysm by promoting perivascular adipose tissue inflammation: 《Life Metabolism》2025年第1期35-49,65,共16页Qing Zhu Da Luo Yining Li Liyang Yu Zixuan Zhang Feng Ouyang Liangkui Li Manxi Lu Changyong Hu Yinuo Dong Chengxin Ma Yan Liang Tong-Jin Zhao Feng-Jung Chen Peng Li Tian-Shu Yang; supported by the National Natural Science Foundation of China(32271334,32100945,and 81871228);the National Key R&D Program of China(2018YFA0506900 and 2018YFA0800301);Shanghai Basic Research Field Project“Science and Technology Innovation Action Plan”(21JC1400400);the Lingang Laboratory(LG-QS-202204-06);the High-Level Medicine Foundation of Shanghai Government(to P.L.);Shanghai Municipal Science and Technology Major Project(2017SHZDZX01).; Abdominal aortic aneurysm(AAA)is strongly correlated with obesity,partially due to the abnormal expansion of abdominal perivascular adipose tissue(PVAT).Cell death-inducing DNA fragmentation factor-like effector C(CID...; 关键词：AAA INFLAMMATION PVAT Cidec CCL2

The deuterated glucose insulin tolerance test:a new tool to delineate insulin-stimulated glucose uptake from suppression of endogenous glucose production: 《Life Metabolism》2025年第1期51-55,共5页Christian A.Unger Marion C.Hope Ⅲ Michael Chase Kettering Cassidy E.Socia Barton C.Rice Darya S.Niamira William E.Cotham Reilly T.Enos; supported by the grants K01-AT010348(National Institutes of Health-National Center for Complementary and Integrative Health);the University of South Carolina Advanced Support for Innovative Research Excellence(ASPIRE)to R.T.E.; Dear Editor,Assessing insulin responsiveness is crucial for understanding the underlying molecular mechanisms that contribute to disruptions in glucose metabolism.In preclinical research,glucose tolerance tests(GTTs)a...; 关键词：ENDOGENOUS HOMEOSTASIS clinical

Chronic cold exposure reprograms feeding-regulated LPL activity in white adipose tissues through hepatic ANGPTL3 and ANGPTL8: 《Life Metabolism》2025年第1期57-61,共5页Yiliang Zhang Shengyang Zhou Runming Zhao Yingzhen Huang Yan Wang; supported by grants from the National Key Research and Development Program of China(2018YFA0800700);the National Natural Science Foundation of China(92057207,32021003,92254308,92357303,323B1015,and 32271223);the 111 Project of China(B16036);the Key Research and Development Program of Hubei province(2019CFA067);Wuhan City(2020020601012211).; Lipoprotein lipase(LPL)mediates peripheral tissue triglyceride(TG)uptake.Hepatic ANGPTL3(A3)and ANGPTL8(A8)form a complex and inhibit LPL activity in the white adipose tissue(WAT)via systematic circulation.ANGPTL4(A4)...; 关键词：LPL WHITE FEEDING

Introduction to the Chief Editors: 《Life Metabolism》2025年第1期66-66,共1页; John R Speakman is an internationally renowned scholar and authority in the field of energy metabolism.He has published>500 articles in Science,Nature,Cell Metabolism,and other journals,and has been cited>17000 times....; 关键词：HAS establishing METABOLISM

Spatial multi-omics characterizes GPR35-relevant lipid metabolism signatures across liver zonation in MASLD: 《Life Metabolism》2024年第6期1-16,共16页Wuxiyar Otkur Yiran Zhang Yirong Li Wenjun Bao Tingze Feng Bo Wu Yaolu Ma Jing Shi Li Wang Shaojun Pei Wen Wang Jixia Wang Yaopeng Zhao Yanfang Liu Xiuling Li Tian Xia Fangjun Wang Di Chen Xinmiao Liang Hai-long Piao; supported by the National Key Research and Development Program of China(2022YFA0806503);the National Natural Science Foundation of China(81972625 and 32201217);Liaoning Revitalization Talents Program(XLYC2002035);Liaoning Science and Technology Innovation Funding(20230101-JH2/1013);the Innovation Program of Science and Research from Dalian Institute of Chemical Physics,Chinese Academy of Sciences(DICP I202129 and DICP I202209);the Science and Technology Innovation Fund(Youth Science and Technology Star)of Dalian(2021RQ009 and 2023RQ040).; Metabolic dysfunction-associated steatotic liver disease(MASLD)is a metabolic disease that can progress to metabolic dysfunction-associated steatohepatitis(MASH),cirrhosis,and cancer.The zonal distribution of biomolec...; 关键词：GPR35 MASLD liver zonation spatial transcriptomics spatial metabolomics

Immuno-electron microscopy localizes Caenorhabditis elegans vitellogenins along the classic exocytosis route: 《Life Metabolism》2024年第6期17-32,共16页Chao Zhai Nan Zhang Xi-Xia Li Xue-Ke Tan Fei Sun Meng-Qiu Dong; funded by the National Natural Science Foundation of China(NSFC-ISF 32061143020 to M.Q.D.,31925026 to F.S.,and 31501160 to X.X.L.);the Ministry of Science and Technology of the People's Republic of China(institutional grants to NIBS,Beijing,a fund of the National High-Level Talents Special Support Program to M.Q.D.);Beijing Municipal Science and Technology Commission(institutional grants to NIBS,Beijing and a fund for cultivation and development of innovation base to M.Q.D.).; Vitellogenins(VITs)are the most abundant proteins in adult hermaphrodite Caenorhabditis elegans.VITs are synthesized in the intes-tine,secreted to the pseudocoelom,matured into yolk proteins,and finally deposited in o...; 关键词：VITELLOGENIN YOLK immuno-EM EXOCYTOSIS Caenorhabditis elegans

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