云南高校图书馆联盟文献共享服务平台- Malignancy Spectrum

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Enhancing tumor radiotherapy sensitivity through metal nanomaterials:A comprehensive review: 《Malignancy Spectrum》2024年第4期243-262,共20页Susu Xiao Xiaoxiao Wang Bo Chen Min Mu Bo Han Nianyong Chen Gang Guo; supported by the Science and Technology Plan Project of Bingtuan(2023AB047);the National Natural Sciences Foundation of China(31971308,82102767,and U1903211);the National S&T Major Project(2019ZX09301-147);the Natural Science Foundation of Sichuan Province(2023NSFSC1866);Sichuan Science and Technology Program(2022YFS0007);Luzhou Science and Technology Plan(2018CDLZ-10).; Radiotherapy(RT)plays a crucial role in tumor treatment and is an indispensable therapeutic approach.However,ionizing radiation often damages the normal tissues surrounding the tumor.Therefore,there is an urgent need ...; 关键词：RADIOTHERAPY NANOMATERIALS RADIOSENSITIZATION high-Z metal TUMOR

The mechanistic role of curcumin and its analogs in NSCLC:An evaluation of cell death in preclinical studies: 《Malignancy Spectrum》2024年第4期263-274,共12页Ela Kesen Boztas Sevki Mustafa Demiroz Hacer Ilke Onen; Lung cancer is the leading malignancy among males and ranks the second in females,with an estimated two million new diagnoses annually.It ranks the first in cancer-related deaths among men and the second,following bre...; 关键词：cell death pathway CURCUMIN curcumin analog non-small cell lung cancer

Hypoxia combined with radiation reverses migration and invasion of head and neck squamous cell carcinoma by remodeling extracellular vesicle-mediated transfer of miR-23b-5p from cancer-associated fibroblasts: 《Malignancy Spectrum》2024年第4期275-289,共15页Chuanshi He Mingzhe Xie Zhimi Zhang Bangrong Cao Huaichao Luo Guiquan Zhu Shun Lu Ling Li; supported by the National Natural Science Foundation of China(81972541,81872196,and 82273307);the Natural Science Foundation of Sichuan Province(2022NSFSC0681 and 2022NSFSC0632)。; Background:Cancer-associated fibroblasts(CAFs),the main matrix components in the tumor microenvironment(TME),play a crucial role in tumor progression.Extracellular vesicles(EVs)as main mediators in intercellular commu...; 关键词：cancer-associated fibroblast extracellular vesicle HYPOXIA RADIOTHERAPY head and neck squamous cell carcinoma

Prediction of genetic profile of breast carcinoma on MRI using a combination of DCE-MRI,DWI,and MR spectroscopy:A prospective observational study: 《Malignancy Spectrum》2024年第4期290-299,共10页Payal Sharma Ishan Kumar Ritu Ojha Seema Khanna Ashish Verma; Background:Classification of breast cancer based on gene expression has emerged as the standard approach in its management,owing to the distinct prognoses and treatment responses observed among different subtypes.The ...; 关键词：breast cancer multiparametric magnetic resonance imaging diffusion-weighted imaging MR spectroscopy algorithm

Comparison of irinotecan/carboplatin versus etoposide/carboplatin for extended disease small cell lung cancer(ED-SCLC):A systematic review and meta-analysis of randomized controlled trials: 《Malignancy Spectrum》2024年第4期300-311,共12页Zeeshan Afzal Sara Hira Xia Song Na Wang; Background:Platinum-based chemotherapy in addition to the nonplatinum agent etoposide is the standard of care for extensive-stage small cell lung cancer(ES-SCLC).However,the front-line chemotherapy regimen is not know...; 关键词：CARBOPLATIN ED-SCLC ETOPOSIDE IRINOTECAN small cell lung cancer

A retrospective observational study of patients with melanoma prescribed combined BRAF and MEK inhibitors in a real-world treatment setting in Japan: 《Malignancy Spectrum》2024年第4期312-322,共11页Kenjiro Namikawa Kok Yew Ngew Zuzanna Lukowicz Ryosuke Kano; funded by Novartis Japan,which developed and marketed TKIs for the treatment of melanoma.; Objective:This study aimed to describe patients with melanoma initiating treatments with dabrafenib plus trametinib(Dab+Tram)or encorafenib plus binimetinib(Enco+Bini)in a real-world setting in Japan.Methods:Data were...; 关键词：BRAF medication use MEK MELANOMA targeted kinase inhibitor

Accuracy of 3D printing template-assisted CT-guided radioactive iodine-125 seed implantation for peripheral locally recurrent rectal cancer:A retrospective study: 《Malignancy Spectrum》2024年第4期323-331,共9页Xuemin Li Hao Wang Yuliang Jiang Zhe Ji Haitao Sun Jinghong Fan Weiyan Li Junjie Wang; The Innovation&Transfer Fund of Peking University Third Hospital for their financial support under grant number BYSYCY2024085.; Objective:This study aimed to investigate the accuracy of needle insertion and dosimetric parameters in three-dimensional printing template(3D-PT)-assisted computed tomography(CT)-guided radioactive iodine-125(125I)se...; 关键词：3D printing template ACCURACY CT guidance needle insertion recurrent rectal cancer

Assessment of risk prediction scores for venous thromboembolism in ambulatory cancer patients with solid tumors receiving chemotherapy:A comparative analysis: 《Malignancy Spectrum》2024年第4期332-338,共7页Hamsaveni Muthukumar Wesley Mannirathil Jose Nikhil Krishna Haridas Anjali Sajikumar Nair Keechilat Pavithran; Objective:Cancer patients have a 4−7-fold increased risk of thrombotic complications due to cancer as well as chemotherapy-induced hypercoagulable state.This study compared the different risk assessment models(Khorana...; 关键词：venous thromboembolism VTE predictors ambulatory cancer patients receiving chemotherapy risk assessment model

Primary malignant melanoma of the breast:A case report without relapse: 《Malignancy Spectrum》2024年第4期339-345,共7页Alejandro Caballero Mario Perez Issis Rodriguez; Objective:This study aimed to report the treatment and outcomes of a patient with primary malignant melanoma of the breast parenchyma using mastectomy as the main treatment.Patient and methods:A 67-year-old female pre...; 关键词：MELANOMA BREAST MALIGNANCY MASTECTOMY

Keep pace with digital innovations: 《Malignancy Spectrum》2024年第4期223-224,共2页Zi Wang Wenfeng Tu Yi Yang; At the beginning of 2024,the artificial intelligence company OpenAI introduced Sora,an innovative artificial intelligence digital product,marking a new milestone in digital technology.In this digital era,our Editorial...; 关键词：artificial TRANSLATE concerned

《Malignancy Spectrum》