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ALDOSE: 作品数：11被引量：40H指数：4; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：王光辉严小军徐继林罗羽陈海敏更多>>; 相关机构：厦门大学第三军医大学宁波大学更多>>; 相关期刊：《Journal of Agricultural Chemistry and Environment》《China Medical Abstracts(Internal Medicine)》《Asian Pacific Journal of Tropical Biomedicine》《Medicinal Plant》更多>>; 相关基金：国家自然科学基金江苏省自然科学基金更多>>

Pathologically relevant aldoses and environmental aldehydes cause cilium disassembly via formyl group-mediated mechanisms: 《Journal of Molecular Cell Biology》2024年第1期15-28,共14页Te Li Min Liu Fan Yu Song Yang Weiwen Bu Kai Liu Jia Yang Hua Ni Mulin Yang Hanxiao Yin Renjie Hong Dengwen Li Huĳie Zhao Jun Zhou; supported by grants from the National Natural Science Foundation of China(31991193 and 32230025);the National Key R&D Program of China(2021YFA1101001).; Carbohydrate metabolism disorders(CMDs),such as diabetes,galactosemia,and mannosidosis,cause ciliopathy-like multiorgan defects.However,the mechanistic link of cilia to CMD complications is still poorly understood.Her...; 关键词：carbohydrate metabolism disorder ALDOSE ALDEHYDE cilium disassembly formyl group calcium influx HDAC6

Inhibition Effects of Salvianolic Acid M and Rosmarinic Acid in Salvia deserta Schang on Human Aldose Reductase: 《Asian Agricultural Research》2019年第8期69-70,共2页Qian HE Jie WU Xinling WANG Jian YANG; Supported by Scientific Research Plan for Colleges and Universities in Xinjiang Uygur Autonomous Region(XJEDU2018Y025); [Objectives]This study aimed to investigate the inhibition effects of two chemical constituents in Salvia deserta Schang on human aldose reductase( AR). [Methods]The isolated salvianolic acid M and rosmarinic acid wer...; 关键词：SALVIA deserta Schang ALDOSE REDUCTASE Salvianolic ACID M Rosmarinic ACID

Inhibitory Effects of Different Extractions of Salvia deserta Schang on Human Aldose Reductase: 《Medicinal Plant》2019年第4期49-50,共2页Qian HE Jie WU Xinling WANG Jian YANG; Supported by Scientific Research Program of Universities in Xinjiang Uygur Autonomous Region(XJEDU2018Y025); [Objectives] To explore whether there are natural substances that inhibit human aldose reductase in different extracts of Salvia deserta Schang.[Methods] The inhibitory activities of human aldose reductase from 28 ext...; 关键词：SALVIA deserta Schang ALDOSE REDUCTASE DIABETIC chronic COMPLICATIONS

The aldose reductase inhibitor epalrestat exerts nephritic protection on diabetic nephropathy in db/db mice through metabolic modulation被引量：16: 《Acta Pharmacologica Sinica》2019年第1期86-97,共12页Jun He Hao-xue Gao Na Yang Xiao-dong Zhu Run-bin Sun Yuan Xie Cai-hong Zeng Jing-wei Zhang Jian-kun Wang Fei Ding Ji-ye Aa Guang-ji Wang; the National Natural Science Foundation of the People's Republic of China (81530098);the National Key Special Project of Science and Technology for Innovation Drugs of China (2017ZX09301013,2015ZX09501001);the Natural Science Foundation of Jiangsu Province (BL2014070);the project of university collaborative innovation center of Jiangsu province (Modern Chinese Medicine Center and Biological Medicine Center).; Epalrestat is an inhibitor of aldose reductase in the polyol pathway and is used for the management of diabetic neuropathy clinically.Our pilot experiments and accumulated evidences showed that epalrestat inhibited po...; 关键词：diabetes DIABETIC NEPHROPATHY POLYOL pathway metabolomics ALDOSE REDUCTASE

Novel insights into the mechanisms whereby isoflavones protect against fatty liver disease: 《World Journal of Gastroenterology》2015年第4期1099-1107,共9页Long-Xin Qiu Tong Chen; Supported by Science and Technology Planning Project of Longyan City,grant No.2012LY44;Fujian Province,China,grant No.2010N0023; Fatty liver disease(FLD) is a growing public health problem worldwide. There is an urgent requirement for alternative and natural medicine to treat this disease. As phytochemicals, isoflavones have attracted considera...; 关键词：ISOFLAVONES FATTY liver disease ALDOSE REDUCTASE F

Diabetes mellitus:An overview on its pharmacological aspects and reported medicinal plants having antidiabetic activity被引量：17: 《Asian Pacific Journal of Tropical Biomedicine》2012年第5期411-420,共10页Patel DK Kumar R Laloo D Hemalatha S; Diabetes mellitus is not a single disease but is a group of metabolic disorders affecting a huge numlier of population in the world.It is mainly characterized by chronic hyperglycemia,resulting from defects in insulin...; 关键词：ALDOSE REDUCTASE ALLOXAN Antioxidant Diabetes mellitus Insulin PHYTOCONSTITUENTS STREPTOZOTOCIN Oral HYPOGLYCEMIC agents

Analysis of apigenin in <i>Blumea balsamifera</i>Linn DC. and its inhibitory activity against aldose reductase in rat lens被引量：1: 《Journal of Agricultural Chemistry and Environment》2012年第1期28-33,共6页Dong Gu Lee So-Youn Mok Changsun Choi Eun Ju Cho Hyun Young Kim Sanghyun Lee; To investigate the therapeutic potentials of na- tural sources, stepwise polarity fractions of Blumea balsamifera were tested for their ability to inhibit aldose reductase (AR) activity in rat lenses. Of these, the et...; 关键词：Blumea balsamifera APIGENIN ALDOSE REDUCTASE Inhibition HPLC

Evaluation of in vitro aldose reductase inhibitory potential of different fraction of Hybanthus enneaspermus Linn F.Muell被引量：4: 《Asian Pacific Journal of Tropical Biomedicine》2012年第2期134-139,共6页Patel DK Kumar R Kumar M Sairarn K Hemalatha S; supported by University Grants Commission,New Delhi(grant No.IT/DEV/08-09/3252/L); Objective:To evaluate the aldose reductase inhibitory(ARI)activity of different fractions of Hybanthus enneaspermus for potential use in diabetic cataract.Methods:Total phenol and flavonoid content of different fracti...; 关键词：Hybanthus enneaspermus TOTAL phenol TOTAL flavonoid Rat lens ALDOSE REDUCTASE Diabetic CATARACT DIFFERENT fractions

Inhibitory effect of two Indian medicinal plants on aldose reductase of rat lens in vitro被引量：4: 《Asian Pacific Journal of Tropical Medicine》2011年第9期694-697,共4页Rajesh Kumar Dinesh Kumar Patel Damiki Laloo Krishnamurthy Sairam Siva Hemalatha; Objective:To assesse the inhibitor) effect of alcoholic extract of two Indian medicinal plants namely Ceasalpinia digyna Rottler and.Alangium lamarckii Thwaits on aldose reductase（AR） of rat lens.Methods:Rats lens w...; 关键词：CAESALPINIA digyna Alangium lamarckii ALDOSE REDUCTASE DIABETIC CATARACT

Glomerular disease: 《China Medical Abstracts(Internal Medicine)》2010年第3期179-181,共3页; 2010361 Effect of ERK signalling pathway and aidose reductase on the expression of fibronectin induced by transforming growth factor β1 in human mesangial cells. HUANG Ping(黄平),et al.Dept Pathol,Shanghai Med Coll,...; 关键词：MESANGIAL FIBRONECTIN glomerular ALDOSE REDUCTASE 黄平 HUANG SOCS collagen segmental

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