METHAMPHETAMINE

作品数：63被引量：83H指数：6
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3'-Deoxyadenosin alleviates methamphetamine-induced aberrant synaptic plasticity and seeking behavior by inhibiting the NLRP3 inflammasome被引量：1
《Neural Regeneration Research》2024年第10期2270-2280,共11页Yize Qi Yao Zhou Jiyang Li Fangyuan Zhu Gengni Guo Can Wang Man Yu Yijie Wang Tengfei Ma Shanwu Feng Li Zhou 
supported by the National Natural Science Foundation of China,No.81971246 (to TM);Opening Foundation of Jiangsu Key Laboratory of Neurodegeneration,Nanjing Medical University,No.KF202204 (to LZ and SF)。
Methamphetamine addiction is a brain disorder characterized by persistent drug-seeking behavior, which has been linked with aberrant synaptic plasticity. An increasing body of evidence suggests that aberrant synaptic ...
关键词：3′-deoxyadenosin hippocampus long-term potentiation METHAMPHETAMINE NOD-like receptor family pyrin domain containing-3(NLRP3)inflammasome synaptic plasticity 
Brain dysfunctions and neurotoxicity induced by psychostimulants in experimental models and humans:an overview of recent findings
《Neural Regeneration Research》2024年第9期1908-1918,共11页Marcello Serra Nicola Simola Alexia E.Pollack Giulia Costa 
supported by PON AIM(PON RICERCA E INNOVAZIONE 2014-2020,-AZIONE I.2.D.D.N.407 DEL 27 FEBBRAIO 2018-“ATTRACTION AND INTERNATIONAL MOBILITY”)(to GC);Zardi-Gori Foundation(research grant 2021)(to MS);intramural funds from the University of Cagliari(to NS);Fondazione CON IL SUD and The U.S.-Italy Fulbright Commission(to AEP).
Preclinical and clinical studies indicate that psychostimulants,in addition to having abuse potential,may elicit brain dysfunctions and/or neurotoxic effects.Central toxicity induced by psychostimulants may pose serio...
关键词：3 4-methylenedioxymethamphetamine AMPHETAMINE caffeine cell cultures cocaine METHAMPHETAMINE METHYLPHENIDATE NEUROTOXICITY nicotine 
Neuronal and peripheral damages induced by synthetic psychoactive substances: an update of recent findings from human and animal studies被引量：2
《Neural Regeneration Research》2020年第5期802-816,共15页Giulia Costa Maria Antonietta De Luca Gessica Piras Jacopo Marongiu Liana Fattore Nicola Simola 
supported by the PRIN 2015(Pr.2015R9ASHT);PON AIM(PON RICERCA E INNOVAZIONE 2014-2020,-AZIONE I.2.D.D.N.407 DEL 27 FEBBRAIO 2018-“ATTRACTION AND INTERNATIONAL MOBILITY”);supported by Autonomous Region of Sardinia(RAS-FSC 2018,Codice intervento:RC_CRP_034;CUP RASSR03071);supported by Fondazione di Sardegna(Progetti Biennali Uni CA,Annualità2017)
Preclinical and clinical studies indicate that synthetic psychoactive substances,in addition to having abuse potential,may elicit toxic effects of varying severity at the peripheral and central levels.Nowadays,toxicit...
关键词：CANNABINOIDS dissociatives HALLUCINOGENS KETAMINE MDMA METHAMPHETAMINE methoxetamine neuroinflammation NEUROTOXICITY NPS 
RIP3/MLKL-mediated neuronal necroptosis induced by methamphetamine at 39℃被引量：9
《Neural Regeneration Research》2020年第5期865-874,共10页Li-Min Guo Zhen Wang Shi-Ping Li Mi Wang Wei-Tao Yan Feng-Xia Liu Chu-Dong Wang Xu-Dong Zhang Dan Chen Jie Yan Kun Xiong 
funded by the National Natural Science Foundation of China,No.81971891(to KX),81571939(to KX),81772134(to KX),81772024(to JY),and 81860781(to FXL);the Key Research and Development Program of Hunan Province of China,No.2018SK2091(to KX);the Natural Science Foundation of Hunan Province of China,No.2017JJ2339(to JY);the Wu Jie-Ping Medical Foundation of the Minister of Health of China,No.320.6750.14118(to KX)
Methamphetamine is one of the most prevalent drugs abused in the world.Methamphetamine abusers usually present with hyperpyrexia (39℃),hallucination and other psychiatric symptoms.However,the detailed mechanism under...
关键词：GSK'872 human brain tissue hyperpyrexia METHAMPHETAMINE mixed LINEAGE kinase domain-like protein necrostatin-1 NECROPTOSIS nerve REGENERATION neural REGENERATION rat CORTICAL neurons receptor-interacting protein-3 synergistic effect 
Implications of alpha-synuclein nitration at tyrosine 39 in methamphetamine-induced neurotoxicity in vitro and in vivo被引量：2
《Neural Regeneration Research》2019年第2期319-327,共9页Hong-Hua Qiao Lin-Nan Zhu Yue Wang Jia-Liang Hui Wei-Bing Xie Chao Liu Ling Chen Ping-Ming Qiu 
supported by the National Natural Science Foundation of China,No.81373240(to PMQ)and 81671865(to PMQ)
Methamphetamine is an amphetamine-type psychostimulant that can damage dopaminergic neurons and cause characteristic pathological changes similar to neurodegenerative diseases such as Parkinson's disease. However, its...
关键词：nerve REGENERATION ALPHA-SYNUCLEIN nitrated α-synuclein Parkinson's disease METHAMPHETAMINE N-nitro-L-arginine ALPHA-SYNUCLEIN aggregation apoptosis NEUROTOXICITY neural REGENERATION 
Tp53 gene mediates distinct dopaminergic neuronal damage in different dopaminergic neurotoxicant models被引量：9
《Neural Regeneration Research》2017年第9期1413-1417,共5页Tao Lu Paul Kim Yu Luo 
supported by NINDS R01NS094152 and R01 NS091213
Tp53, a stress response gene, is involved in diverse cell death pathways and its activation is implicated in the pathogenesis of Parkinson＇s disease. However, whether the neuronal Tp53 protein plays a direct role in ...
关键词：Parkinson＇s disease TP53 1-methyl-4-phenyl-1 2 3 6-tetrahydropyridine NEUROTOXICITY apoptosis METHAMPHETAMINE 
Protective effect of alpha-synuclein knockdown on methamphetamine-induced neurotoxicity in dopaminergic neurons
《Neural Regeneration Research》2014年第9期951-958,共8页Yunchun Tai Ling Chen Enping Huang Chao Liu Xingyi Yang Pingming Qiu Huijun Wang 
supported by the National Natural Science Foundation of China,No.81072506
The over-expression of α-synuclein is a major factor in the death of dopaminergic neurons in a methamphetamine-induced model of Parkinson’s disease. In the present study, α-synuclein knockdown rats were created by ...
关键词：nerve regeneration Α-SYNUCLEIN Parkinson’s disease METHAMPHETAMINE dopaminergic neurons NEUROTOXICITY STRIATUM oxidative stress apoptosis NSFC grant neural regeneration 
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