EMBRYOTOXICITY

作品数：6被引量：8H指数：2
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相关领域：医药卫生更多>>
相关作者：何庆文徐敏更多>>
相关机构：香港浸会大学更多>>
相关期刊：《Journal of Health Science》《Journal of Ocean University of China》《Chinese Journal of Integrative Medicine》《Acta Pharmacologica Sinica》更多>>
相关基金：国家自然科学基金北京市自然科学基金更多>>
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Genotoxicity and Embryotoxicity Study of Bicyclol Methyl Ether, Main Impurity in Bicyclol被引量：4
《Chinese Journal of Integrative Medicine》2019年第10期743-749,共7页ZHANG Qian-qian LI Qiang DONG Lin LI Wan-fang LI Chao WANG Ai-ping WEI Jin-feng JIN Hong-tao 
Objective: To assess the genotoxicity and embryotoxicity of bicyclol methyl ether(BME), the main impurity in bicyclol. Methods: Five concentrations of BME(0.5, 5, 50, 500 and 5000 μg/plate) were used in the Ames test...
关键词：BICYCLOL methyl ether GENOTOXICITY EMBRYOTOXICITY AMES TEST chromosome aberration TEST zebrafish 
Comparison of the In Vitro and In Vivo Toxic Effects of Three Sizes of Zinc Oxide(ZnO)Particles Using Flounder Gill(FG)Cells and Zebrafish Embryos被引量：1
《Journal of Ocean University of China》2017年第1期93-106,共14页HAN Li ZHAI Yanan LIU Yang HAO Linhua GUO Huarong 
supported by the National Natural Science Foundation of China(Grant Nos.41076075,31472274 and 31172391);Scholarship Foundation for Excellent Scientists of Shandong Province(Grant No.BS2011 SW054);open foundation from Institute of Marine Biodiversity and Evolution(Grant No.20132017)
Nano-sized zinc oxide(n ZnO) particles are one kind of the most commonly used metal oxide nanoparticles(NPs). This study compared the cytotoxic and embryotoxic effects of three increasing sized ZnO particles(φ30 nm, ...
关键词：zinc oxide (ZnO) nanoparticles cytotoxicity EMBRYOTOXICITY ZEBRAFISH fish CELLS 
Embryotoxicity and Teratogenicity of Rhein
《Journal of Health Science》2014年第4期180-184,共5页Yanchun Hu Chaorong Zeng Fei Liao Hui Tan Lei Wu Xi Liu Zhicai Zuo Junliang Deng Anchun Cheng Yahui Wei 
To study the effect ofrhein on embryo development of rats and fetuscs, the SD rats were divided into rhein （87.5, 175 and 350 mg/kg） group and negative control group treated with 0.5% CMC （carboxyl methyl cellulose...
关键词：RHEIN EMBRYOTOXICITY teratogenicity. 
Inhibition of Embryonic Stem Cell Differentiation by Gold Nanoparticles
《Journal of Pharmacy and Pharmacology》2014年第4期243-256,共14页Sumi Dinda Sarah Rasul Chaudhry Naimisha Reddy Beeravolu Christina McKee Ghulam RasulChaudhry 
Acknowledgments This research was supported by the OU-WB （Oakland University-William Beaumont） Interdisciplinary Research Program, Oakland University, Michigan Research Excellence Fund, and the SIBHI （Summer Institute of Bioengineering and Health Informatics）, which was funded by the National Institutes of Health and the National Science Foundation. We are thankful for Ms. Loan Dong and Dr. Harvey Qu for TEM studies and statistical analysis, respectively.
Nanomaterials are attractive for use in technological advancements because of their small size and unique properties. As a result, there has been a rapid increase in the production and applications of nanomaterials. N...
关键词：NANOMATERIALS EMBRYOTOXICITY PLURIPOTENCY SELF-RENEWAL Oct 4 
Dihydroartemisinin promotes angiogenesis during the early embryonic development of zebrafish被引量：3
《Acta Pharmacologica Sinica》2013年第8期1101-1107,共7页Qian BA Juan DUAN Jia-qiang TIAN Zi-liang WANG Tao CHEN Xiao-guang LI Pei-zhan CHEN Song-jie WU Li XlANG Jing-quan LI Rui-ai CHU Hui WANG 
Aim： To investigate the embryotoxicity of dihydroartemisinin （DHA）, the main active metabolite of artemisinin, in zebrafish, and explore the corresponding mechanisms. Methods： The embryos of wild type and TG （flk...
关键词：ARTEMISININ DIHYDROARTEMISININ ZEBRAFISH ilk1 VEGF ANGIOGENESIS EMBRYOTOXICITY 
Chinese Young Researcher Symposia on Pharmacology （Track 2） Establishment and application of an in vitro embryotoxicity screening test
《中国药理通讯》2005年第2期26-27,共2页YanCHANG Hai-xiaLIN Qi-bingMEI Bei-liQIAN 
AIM Developmental toxicity testing to current international guidelines involves exposure of pregnant animals, mostly rats and rabbits, and subsequent assessment of toxic effects in their fetuses. Alternative methods h...
关键词：中国 青年研究员 座谈会 药理学 应用软件 胚胎毒性 选择性 
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