RESOLVINS

作品数:10被引量:29H指数:3
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相关领域:医药卫生更多>>
相关作者:周克元张俊杰蔡春王志福王彦青更多>>
相关机构:广东医学院复旦大学上海医学院更多>>
相关期刊:《Journal of Cosmetics, Dermatological Sciences and Applications》《生物化学与生物物理进展》《World Journal of Clinical Cases》《Chinese Medical Journal》更多>>
相关基金:国家自然科学基金更多>>
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Future applications of exosomes delivering resolvins and cytokines in facilitating diabetic foot ulcer healing
《World Journal of Diabetes》2023年第1期35-47,共13页Joshua P B Littig Rebecca Moellmer Devendra K Agrawal Vikrant Rai 
Supported by the Intramural Grant IMR Rai 12397B from the Western University of Health Sciences,Pomona,California;the Grants from the National Institutes of Health,United States,R01 HL144125 and R01 HL147662.
Type 2 diabetes mellitus(T2DM)increases the risk of many lethal and debilitating conditions.Among them,foot ulceration due to neuropathy,vascular disease,or trauma affects the quality of life of millions in the United...
关键词:Diabetic foot ulcer Chronic inflammation AMPUTATION EXOSOMES CYTOKINES RESOLVINS 
Targeting resolvins in cholestatic liver injury被引量:1
《Hepatobiliary Surgery and Nutrition》2021年第5期689-691,共3页Luis AVidela Rodrigo Valenzuela 
In general terms,the acute inflammatory reaction in conditions of infection or tissue damage is a response of the immune system to cope with survival and return to homeostasis.Temporarily,the reaction is initiated by ...
关键词:protective ACUTE HOMEOSTASIS 
血管n-3二十二碳五烯酸衍生的D系列Resolvins的生成和昼夜调节障碍增加全身性炎症与心血管病
《中华高血压杂志》2018年第3期275-275,共1页刘莉 叶鹏 Colas RA Souza PR Walker ME Burton M Marques RM Zasona Z Curtis AM Dalli J 
昼夜机制对调节宿主反应至关重要。最近的研究发现了一种特异性促炎症消退介质(specialized proresolving mediators,SPM)的新型介质家族,其可在不干扰免疫应答的情况下终止炎症。然而关于其昼夜调节情况知之甚少。该研究调查了人体SP...
关键词:全身性炎症 调节障碍 心血管病 昼夜 碳五烯酸 n-3 十二 外周血白细胞 
Resolvins and omega three polyunsaturated fatty acids: Clinical implications in inflammatory diseases and cancer被引量:3
《World Journal of Clinical Cases》2016年第7期155-164,共10页Kazuki Moro Masayuki Nagahashi Rajesh Ramanathan Kazuaki Takabe Toshifumi Wakai 
Supported by The Japan Society for the Promotion of Science(JSPS)Grant-in-Aid for Scientific Research,Nos.15H05676 and 15K15471 for Nagahashi M and No.15H04927 for Wakai T;supported by the Uehara Memorial Foundation,Nakayama Cancer Research Institute,Takeda Science Foundation,Tsukada Medical Foundation;supported by NIH/NCI,No.R01CA160688;supported by Susan G.Komen Investigator Initiated Research,No.IIR12222224;supported by Tohoku Cancer Professional Training Promotion Plan
Inflammation is a central process in several disorders and contributes to cancer progression. Inflammation involves a complex cascade of pro-inflammatory and anti-inflammatory signaling events with protein and lipid m...
关键词:ANTI-INFLAMMATORY lipid MEDIATORS Resolvin OMEGA THREE polyunsaturated fatty acids Inflammatory diseases CANCER 
<i>In Vitro</i>and <i>in Vivo</i>Anti-Inflammatory Effect of a Biotechnologically Modified Borage Seed Extract: Evidence for Lipid Pro-Resolving Mediators’ Implication in the Enhancement of Psoriatic and Atopic Dermatitis Lesions
《Journal of Cosmetics, Dermatological Sciences and Applications》2015年第2期151-160,共10页Gérald Chene Vincent Baillif Emeline Van Goethem Jean-Eric Branka Toni Ionescu Géraldine Robert Luc Lefeuvre 
Aim: Resolvins, maresins and lipoxins are lipid mediators issued from essential polyunsaturated fatty acids which are the first anti-inflammatory and pro-resolving signals identified during the resolution phase of inf...
关键词:Human Skin Biotechnologically MODIFIED Borage EXTRACT Interleukins Inflammation Psoriasis Atopic Dermatitis RESOLVINS Maresins LIPOXINS 
Effects of resolvin D1 on inflammatory responses and oxidative stress of lipopolysaccharide-induced acute lung injury in mice被引量:10
《Chinese Medical Journal》2014年第5期803-809,共7页Yuan Ruixia Wang Lei Yao Chengyue Wu Qingping Marie Christelle Xie Wanli Zhang Xingcai Sun Wei Wang Huiqing Yao Shanglong 
This study by grants from the National Natural Science Foundation of China
Background A variety of inflammatory mediators and effector cells participate together in acute lung injury,and lead to secondary injury that is due to an inflammatory cascade and secondary diffuse lung parenchyma inj...
关键词:acute lung injury resolvin D1 RESOLVINS oxidative stress 
Resolvin-D1 inhibits interleukin-8 and hydrogen peroxide production induced by cigarette smoke extract in 16HBE cells via attenuating NF-κB activation被引量:6
《Chinese Medical Journal》2014年第3期511-517,共7页Dong Jiajia Zhang Mingke Liao Zenglin Wu Wei Wang Tao Chen Lei Yang Ting Guo Lingli Xu Dan Wen Fuqiang 
This study was supported by grants from the National Natural Science Foundation of China and China Medical Board of New York to Dr.Wen Fuqiang (No.31171103,No.81230001 and No.06834).
Background Cigarette smoke induced airway inflammation plays a role in pathogenesis of airway inflammation.Resolvin-D1 derived from omega-3 polyunsaturated fatty acids is an endogenous anti-inflammatory and proresolvi...
关键词:RESOLVINS airway inflammation oxidative stress INTERLEUKIN-8 NF-ΚB 
Resolvins抗炎镇痛研究进展被引量:2
《中国疼痛医学杂志》2012年第6期375-376,379,共3页王志福 米文丽 毛应启梁 王彦青 吴根诚 
国家自然科学基金面上项目(项目编号:81072875),国家自然科学基金面上项目(项目编号:30970975)
Resolvins是来源于ω-3多不饱和脂肪酸(polyunsaturated fatty acids,PUFA)、经相应酶催化合成的一种脂类介质,由于其独特的抗炎镇痛作用而被大家所关注。本文就近年来关于Resolvins的合成、代谢、生物学功能及其与炎症和疼痛疾患的关...
关键词:RESOLVINS 脂加氧酶 疼痛 炎症 
A defect in the activities of △~6 and △~5 desaturases and pro-resolution bioactive lipids in the pathobiology of non-alcoholic fatty liver disease被引量:2
《World Journal of Diabetes》2011年第11期176-188,共13页Undurti N Das 
Supported by Ramalingaswami Fellowship of the Department of Biotechnology, India;a grant from the Defense Research and Development Organisation, New Delhi, India
Non-alcoholic fatty liver disease (NAFLD) is a low-grade systemic inflammatory condition, since liver and adipose tissue tumor necrosis factor-α (TNF-α) and TNF receptor 1 transcripts and serum TNF-α levels are inc...
关键词:PROSTAGLANDINS Lipids Arachidonic ACID Eicosapentaenoic ACID Non-alcoholic fatty liver disease Docosahexaenoic ACID LIPOXINS RESOLVINS Protectins Cytokines Free radicals HYPERLIPIDEMIA 
n-3脂肪酸代谢产物抗炎作用的研究进展被引量:6
《生物化学与生物物理进展》2011年第1期20-27,共8页张俊杰 周克元 蔡春 
国家自然科学基金资助项目(30672741)~~
炎症反应是机体正常组织对感染和损伤的应答,然而过度的炎症反应往往会引起急性和慢性疾病的发生.最近研究发现,由n-3多不饱和脂肪酸二十碳五烯酸和二十二碳六烯酸代谢产生的resolvins和protectins两类化合物,具有很强的抗炎和炎症修复...
关键词:RESOLVINS protectinD1 N-3脂肪酸 炎症 
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