IMMUNOMODULATION

作品数：259被引量：1340H指数：16
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相关领域：医药卫生更多>>
相关作者：龚明玉商亚珍李素婷周晓霞王宝元更多>>
相关机构：武汉大学承德医学院南京医科大学南京大学更多>>
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相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划北京市自然科学基金更多>>
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  • 期刊=Regenerative Biomaterialsx
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Constructing a highly efficient multifunctional carbon quantum dot platform for the treatment of infectious wounds
《Regenerative Biomaterials》2024年第6期137-148,共12页Hangzhen Zhang Jiafan Bai Xiangli Chen Linyu Wang Wenzhen Peng Yuancong Zhao Jie Weng Wei Zhi Jianxin Wang Kai Zhang Xingdong Zhang 
supported by The National Key Technologies R&D Program of China(grant number 2016YFC1102001);the Natural Science Foundation of Sichuan Province(grant number 2022NSFSC0369).
Antibiotic resistance poses a huge threat to public health,which has increased the difficulty and transmission of disease treatment,as well as the burden and cost of medical institutions.In response to the current pro...
关键词：multifunctional fluorescent carbon dots ANTIBACTERIAL IMMUNOMODULATION bacterial labeling promoting angiogenesis 
Biomaterials for immunomodulation in wound healing
《Regenerative Biomaterials》2024年第5期1-22,共22页Ying Wang Katrina Vizely Chen Yu Li Karen Shen Amid Shakeri Ramak Khosravi James Ryan Smith Eugene Alfonzo II Alteza Yimu Zhao Milica Radisic 
the Canadian Institutes of Health Research(CIHR)Foundation Grant FDN-167274;Natural Sciences and Engineering Research Council of Canada(NSERC)Discovery Grant(RGPIN 326982-10);Stem Cell Network Impact Award 920530 and National Institutes of Health Grant 2R01 HL076485.
The substantial economic impact of non-healing wounds,scarring,and burns stemming from skin injuries is evident,resulting in a financial burden on both patients and the healthcare system.This review paper provides an ...
关键词：IMMUNOMODULATION peptide-based biomaterials innate immunity angiogenesis for wound healing cellular response 
dECM restores macrophage immune homeostasis and alleviates iron overload to promote DTPI healing
《Regenerative Biomaterials》2024年第2期100-113,共14页Ju Zhang Ruijuan Si Yu Gao Hui Shan Qi Su Zujian Feng Pingsheng Huang Deling Kong Weiwei Wang 
supported by the National Natural Science Foundation of China(81701838);the Natural Science Foundation of Shandong(ZR2022MH037).
Due to its highly insidious and rapid progression,deep tissue pressure injury(DTPI)is a clinical challenge.Our previous study found that DTPI may be a skeletal muscle injury dominated by macrophage immune dysfunction ...
关键词：Deep tissue pressure injury HYDROGEL IMMUNOMODULATION tissue repair 
Quercetin-solid lipid nanoparticle-embedded hyaluronic acid functionalized hydrogel for immunomodulation to promote bone reconstruction被引量：1
《Regenerative Biomaterials》2023年第1期713-728,共16页Pinghui Zhou Bomin Yan Bangguo Wei Liangmin Fu Ying Wang Wenrui Wang Li Zhang Yingji Mao 
supported by grants from the 512 Talents Development Project of Bengbu Medical College(by51201206,by51202302 and by51202309);the Domestic Visiting and Training Program for Outstanding Young Backbone Teachers in High Schools(gxgnfx2022036);the Natural Science Research Project of the Anhui Educational Committee(KJ2021ZD0089 and 2022AH020086);the Scientific Research Foundation of Bengbu Medical College(2021bypd006);Nature Science Research Project of Anhui Province(2108085MH294).
Bone defects are a persistent challenge in clinical practice.Although repair therapies based on tissue-engineered materials,which are known to have a crucial role in defective bone regeneration,have gathered increased...
关键词：QUERCETIN HYDROGELS MACROPHAGES inflammatory microenvironments bone tissue engineering 
Recombinant humanized collagen remodels endometrial immune microenvironment of chronic endometritis through macrophage immunomodulation被引量：6
《Regenerative Biomaterials》2023年第1期853-869,共17页Shuang You Yun Zhu Hu Li Fan He Shuaibin Liu Xia Yang Li Wang Hui Zeng Jingcong Dai Lina Hu 
supported by Scientific and Technological Research Program of Chongqing Municipal Education Commission(Grant No.KJCXZD2020017).
Recently,evidence has suggested that chronic endometritis(CE)is a crucial factor associated with infertility and failure of assisted reproductive techniques,prompting concern in the reproductive field.Studies have sho...
关键词：chronic endometritis recombinant humanized collagen type III collagen MACROPHAGES 
Effect of micro/nano-sheet array structures on the osteo-immunomodulation of macrophages被引量：4
《Regenerative Biomaterials》2022年第1期888-899,共12页Xinhui Zheng Lan Chen Ji Tan Jianhua Miao Xuanyong Liu Tieyi Yang Zhihong Ding 
financially supported by the National Natural Science Foundation of China(51831011,31870944);Medical discipline Construction Project of Pudong Health Committee of Shanghai(PWYts2021-05);Postdoctoral Science Foundation of China(2021 M693260).
The immune response induced by surface topography crucially determines the implant success.However,how the immune response is mediated by the size of surface topography remains unclear.Hence,various biocompatible Mg-A...
关键词：micro-nano topography IMMUNOMODULATION MACROPHAGES OSTEOGENESIS 
Mg(OH)_(2)nanosheets on Ti with immunomodulatory function for orthopedic applications被引量：3
《Regenerative Biomaterials》2022年第1期325-334,共10页Yue He Mengyu Yao Jielong Zhou Juning Xie Changxiang Liang Dong Yin Shuaihao Huang Yu Zhang Feng Peng Shi Cheng 
supported by the National Natural Science Foundation of China(52001076);the Scientific and Technological Projects of Guangzhou,China(202102020431);the NSFC Incubation Project of Guangdong Provincial People’s Hospital(KY0120220044);the Guangdong Basic and Applied Basic Research Foundation(2021A1515110135).
Macrophages play a vital role for guiding the fate of osteogenesisrelated cells.It is well known that nano-topography and bioactive ions can directly enhance osteogenic behavior.However,the effects of nano-structure c...
关键词：IMMUNOMODULATION TITANIUM nano-magnesium hydroxide OSTEOGENESIS 
Rational design of hydrogels for immunomodulation被引量：3
《Regenerative Biomaterials》2022年第1期979-1000,共22页Wenhuan Bu Yuanhao Wu Amir M.Ghaemmaghami Hongchen Sun Alvaro Mata 
supported by the ERC Proof-of-Concept Grant(MINGRAFT),the AO Foundation Grant(AOCMF-17-19M);the Medical Research Council(UK Regenerative Medicine Platform Acellular/Smart Materials-3D Architecture,MR/R015651/1);the National Natural Science Foundation of China(81870741,82001023),China Postdoctoral Science Foundation(2019M661177);Natural Science Foundation of Liaoning Province(2020-MS-154);China Scholarship Council([2020]50).
The immune system protects organisms against endogenous and exogenous harm and plays a key role in tissue development,repair and regeneration.Traditional immunomodulatory biologics exhibit limitations including degrad...
关键词：HYDROGELS IMMUNOMODULATION physical properties chemical properties 
Calcium silicate enhances immunosuppressive function of MSCs to indirectly modulate the polarization of macrophages被引量：2
《Regenerative Biomaterials》2021年第6期136-147,共12页Haiyan Li Wenrui Wang Jiang Chang 
supported by the National Natural Science Foundation of China(Grant Nos.31771024 and 31971274).
Bioactive silicate ceramics(BSCs)have been widely reported to be able to induce bone tissue regeneration,but the underlying mechanisms have not been fully elucidated.Previous studies have reported that ionic products ...
关键词：calcium silicate MSCS MACROPHAGE IMMUNOMODULATION 
In vitro immunomodulation of magnesium on monocytic cell toward anti-inflammatory macrophages被引量：9
《Regenerative Biomaterials》2020年第4期391-401,共11页Lei Sun Xiaoyu Li Menghan Xu Fenghe Yang Wei Wang Xufeng Niu 
financially supported by the National Natural Science Foundation of China(11872097,31872735);Beijing Natural Science Foundation(L182017);the Fundamental Research Funds for the Central Universities(YWF-19-BJ-J-234);the 111 Project(B13003);the International Joint Research Center of Aerospace Biotechnology and Medical Engineering,Ministry of Science and Technology of China.
Biodegradable magnesium(Mg)has shown great potential advantages over current bone fixation devices and vascular scaffold technologies;however,there are few reports on the immunomodulation of corrosive Mg products,the ...
关键词：IMMUNOMODULATION MAGNESIUM THP-1 MACROPHAGE polarization 
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