FLAVONE

作品数:97被引量:303H指数:10
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相关领域:医药卫生理学更多>>
相关作者:邱声祥宋志军招雪晴方炎明曹文斌更多>>
相关机构:北京大学云南大学中国科学院华南植物园中国科学院成都生物研究所更多>>
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相关基金:国家自然科学基金中国博士后科学基金国家重点基础研究发展计划北京市自然科学基金更多>>
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Luteolin,a common flavone in vegetables,acts as a hormetin possessing neurotrophic function:signaling mediated by inducing mitochondrial stress
《Food Science and Human Wellness》2025年第2期569-580,共12页Alex Xiong Gao Tracy Chenxi Xia Maggie Suisui Guo Gary Kawing Yuen Kevin Qiyun Wu Tina Tingxia Dong Karl Wah-Keung Tsim 
supported by Hong Kong RGC-GFC 16100921;Hong Kong RGC Theme-based Research Scheme(T13-605/18-W);Hong Kong Innovation Technology Fund(PRP/076/20FXITCPD/17-9,MHP/004/21);PD18SC01 and HMRF18SC06;HMRF20SC07,AFD20SC01;Shenzhen Science and Technology Innovation Committee(ZDSYS201707281432317)。
This study aims to uncover the hormetic process of luteolin,a common dietary flavone,in neuronal cells through its role in inducing mitochondrial stress.In rat pheochromocytoma PC12 cells,luteolin at low concentration...
关键词:Flavonoids HORMESIS Mitochondrial membrane potential Autophagy MITOPHAGY 
Semen podocarpi extract enhances radiosensitivity in nasopharyngeal carcinoma cells via Raf/MEK/ERK signaling pathway
《Asian Pacific Journal of Tropical Biomedicine》2025年第2期75-84,共10页Fan-Yan Zeng Zeng-Qiong Huang Yong-Cu Sun Xiao-Dong Zhu 
supported by the Project of Administration of Traditional Chinese Medicine of Guangxi Zhuang Autonomous Region(grant number GZSY22-69);the Middle/Young aged Teachers’Research Ability Improvement Project of Guangxi Higher Education(grant number 2024KY0120).
Objective:To investigate the chemical components of Semen podocarpi extract(SPE)and its effect on nasopharyngeal carcinoma cells and CNE-2R cells.Methods:Chemical components in SPE were identified by UPLC-MS/MS.CCK-8 ...
关键词:Podocarpus macrophyllus Nasopharyngeal carcinoma RADIOSENSITIZATION Chemical composition Inumakilactone Podocarpus flavone 
Flavone improves liver damage in nicotine-exposed rats via the Nrf2/HO-1 pathway
《Asian Pacific Journal of Tropical Biomedicine》2024年第8期341-349,共9页Nora A.Elsayed Fatma SM Moawed Esraa SA Ahmed Ahmed Hammad Omayma AR Abo-Zaid 
Objective:To assess the hepatoprotective effects of flavone on nicotine-induced liver damage.Methods:Thirty-six rats were allocated into six groups:the control group,the nicotine group,the flavone alone groups(10 and ...
关键词:FLAVONE NICOTINE Liver NRF2 HO-1 NF-κB 
Natural variation of GmFNSII-2 contributes to drought resistance by modulating enzyme activity in soybean
《The Crop Journal》2024年第2期529-539,共11页Huihui Gao Pengcheng Wei Yongzhe Gu Pengbin Tang Yifan Shen Lei Yang Linxin Dong Haowei Zheng Kuo Shu Mayamiko Masangano Bin Dong Long Miao Jiajia Li Lijuan Qiu Xiaobo Wang 
supported by grants from the National Key Research and Development Program of China(2023YFF1000404,2022YFF10001501);the National Natural Science Foundation of China(32171971)。
As an essential crop that provides vegetable oil and protein,soybean(Glycine max(L.)Merr.)is widely planted all over the world.However,the scarcity of water resources worldwide has seriously impacted on the quality an...
关键词:Drought stress Flavone synthase GmFNSII-2 Natural variation Drought response element 
Functional characterization of two flavone synthase Ⅱ members in citrus
《Horticulture Research》2023年第7期250-264,共15页Juan Zheng Chenning Zhao Zhenkun Liao Xiaojuan Liu Qin Gong Chenwen Zhou Yilong Liu Yue Wang Jinping Cao Lili Liu Dengliang Wang Chongde Sun 
This research was supported by the China Postdoctoral Science Foundation(2021 M700124 and 2021 M692845);the National Natu-ral Science Foundation of China(32072132);the Fundamental Research Funds for the Central Universities(K20220104).
Polymethoxylated flavones(PMFs),the main form of flavones in citrus,are derived from the flavone branch of the flavonoid biosynthesis pathway.Flavone synthases(FNSs)are enzymes that catalyze the synthesis of flavones ...
关键词:SYNTHESIS converted characterization 
6-Methyl flavone inhibits Nogo-B expression and improves high fructose diet-induced liver injury in mice被引量:1
《Acta Pharmacologica Sinica》2023年第11期2216-2229,共14页Ke Gong Zhen Zhang Sha-sha Chen Xin-ran Zhu Meng-yao Wang Xin-yue Yang Chen Ding Ji-hong Han Qing-shan Li Ya-jun Duan 
Support was provided by China NSFC grants U22A20272 and 82173807 to YJD,81973316 to JHH;Tianjin Municipal Science and Technology Commission of China Grant 20JCZDJC00710 and the Fundamental Research Funds for the Central Universities(Nankai University)63211045 to JHH.
Excessive fructose consumption increases hepatic de novo lipogenesis, resulting in cellular stress, inflammation and liver injury. Nogo-B is a resident protein of the endoplasmic reticulum that regulates its structure...
关键词:metabolic syndrome glycolipid metabolism liver injury high fructose 6-methyl flavone Nogo-B 
Sortilin-induced lipid accumulation and atherogenesis are suppressed by HNF1b SUMOylation promoted by flavone of Polygonatum odoratum
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2023年第11期998-1013,共16页Fang LIU Shirui CHEN Xinyue MING Huijuan LI Zhaoming ZENG Yuncheng LV 
supported by the Natural Science Foundation of Guangxi Zhuang Autonomous Region,China (No.2019JJA140728);the Horizontal Cooperation Project with Hunan Mingshun Pharmaceutical Co.,Ltd. (No.2021GLHX02);the Guangxi Province Postgraduate Co-training Base for Cooperative Innovation in Basic Medicine of Guilin Medical University (No.Gui Xue Wei[2020]7).
This study aims to investigate the impact of hepatocyte nuclear factor 1β(HNF1b)on macrophage sortilin-mediated lipid metabolism and aortic atherosclerosis and explore the role of the flavone of Polygonatum odoratum(...
关键词:ATHEROSCLEROSIS Lipid accumulation Hepatocyte nuclear factor 1β(HNF1b) Flavone of Polygonatum odoratum SUMOYLATION 
Luteolin: A flavone with myriads of bioactivities and food applications被引量:3
《Food Bioscience》2023年第2期79-92,共14页Sneh Punia Bangar Priyanka Kajla Vandana Chaudhary Nitya Sharma Fatih Ozogul 
Flavonoids are increasingly applied in foods to promote their functional properties,human health,and overall wellbeing.Luteolin,a polyphenolic plant flavonoid,is recognized as one of the plausible bioactive components...
关键词:FLAVONOIDS LUTEOLIN BIOSYNTHESIS BIOACTIVITIES APPLICATIONS 
Geranylated or prenylated flavonoids from Cajanus volubilis
《Chinese Journal of Natural Medicines》2023年第4期292-297,共6页RAO Li SU Yu HE Qian YE Jia LIU Yu FAN Yue HU Feng ZHOU Zhen GAN Lishe ZHANG Yonghui ZHANG Chuanrui 
supported by the National Natural Science Foundation of China(No.22177016);the Natural Science Foundation of Chongqing(No.cstc2020jcyj-msxmX0537);the Open Project of State Key Laboratory of Natural Medicines(No.SKLNMKF202011).
Five new flavonoid derivatives,cajavolubones A-E(1-5),along with six known analogues(6-11)were isolated from Cajanus volubilis,and their structures were elucidated by spectroscopic analysis and quantum chemical calcul...
关键词:Cajanus volubilis Geranylated chalcone Prenylated flavone Prenylated isoflavanone CYTOTOXICITY 
Tetrastigma hemsleyanum flavones exert antihepatic carcinoma property both in vitro and in vivo被引量:2
《Food Quality and Safety》2021年第4期398-411,共14页Yangyang Liu Yonglu Li Wen Chen Xiang Ye Ruoyi Jia Lushuang Yu Qiong Tang Pengcheng Tu Yong Jiang Qiang Chu Xiaodong Zheng 
This research was based on the‘Functional food research and development of Tetrastigma hemsleyanum’funded by the Shanghai Zhengyue Enterprise Management Co.,Ltd.and the Science and Technology Department of Zhejiang Province(No.2018C02045),China.
Tetrastigma hemsleyanum(T.hemsleyanum)has been regarded as an anticancer food in China.However,its corresponding mechanisms remains unclear.Thus,in this study,the antitumor activity of flavones-rich fraction of root o...
关键词:Tetrastigma hemsleyanum human hepatoellular carcinomas(HepG2) FLAVONE ANTITUMOR apoptosis 
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