One of the main immune-mediated diseases that lead to avoidable blindness is non-infectious uveitis. Glucocorticoids are the first-line therapy choice for noninfectious uveitis;however, biologics are also showing prom...
The coronavirus disease 2019(COVID-19)pandemic is caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Hepatic involvement is common in SARS-CoV-2-infected individuals.It is currently accepted that th...
Recently,an outbreak of severe acute hepatitis of unknown etiology in children has been reported in more than 27 countries worldwide.However,information on its prevalence in different countries and regions is still la...
Hainan Natural Science Foundation for Innovation Research Team(No.820CXTD448);Hainan Key R&D International Science and Technology Cooperation Project(GHYF2022011);the Scientific and Technology Cooperation of Key Research and Development in Hainan Province(No.ZDYF2020223);Major Science and Technology Special Projects in Hainan Province(No.ZDKJ2021036);National Natural Science Foundation of China(No.81860001,82011530049,82160012);It was also a project supported by Hainan Provincial Clinical Medical Center.
Autophagy is a highly conserved catabolic process, involving the degradation of cellular components, including damaged organelles, denatured proteins and various pathogens. It is a defense and stress mechanism for mai...
supported by the CAMS Innovation Fund for Medical Science(CIFMS 2016-I2M-1-014);the National Key Plan for Scientific Research and Development of China(2016YFD0500300);National Key R&D Program of China(2020YFA0707600);Beijing Municipal Science and Technology Project(Z201100001020005)。
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has caused a devastating pandemic worldwide.Vaccines and antiviral drugs are the most promising candidates for combating this global epidemic,and scientists a...
Our increase in knowledge of the pathophysiology of non-infectious uveitis(NIU)and other immune-mediated diseases has been mirrored over the last two decades by the expansion of therapeutic options in the realm of imm...
This study was supported by a National Eye Institute Grant K08 EY022948,a Collins Medical Trust Grant,and a Research to Prevent Blindness Career Development Award(PL);This study was also supported by core grant P30 EY010572 from the National Institute of Health(Bethesda,MD)and by unrestricted departmental funding from Research to Prevent Blindness(New York,NY).PL is also the recipient of an Alcon Research Institute Young Investigator Award and OHSU Physician-Scientist award,as well as recipient of a Thome Foundation award.
An intestinal dysbiosis is connected to a number of inflammatory diseases through various mechanisms relating to its effect on immune cell function and differentiation.This is a review of the literature summarizing ou...
Introduction: Senegal has pioneered the implementation of peritoneal dialysis (PD) in West Africa, practicing it since 2004. Non-infectious complications are a significant cause of failure of this technique and the tr...
Non-infectious uveitis is one of the leading causes of preventable blindness worldwide. Long-term immunosuppressive treatment is generally required to achieve durable control of inflammation in posterior and panuveiti...
· AIM: To evaluate the safety and efficacy of dexamethasone implant in patients with non-infectious posterior uveitis with cystoid macular edema(CME).·METHODS: Retrospective analysis of patients reports with CME sec...