DAUNOMYCIN

作品数：9被引量：0H指数：0
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相关领域：医药卫生更多>>
相关作者：刘芳包蕙心陈建华杜世彧邹萍更多>>
相关机构：广东药科大学中国科学院华中科技大学同济医学院附属协和医院黑龙江省科学院更多>>
相关期刊：《Acta Pharmacologica Sinica》《Chinese Journal of Cancer Research》《Chinese Journal of Chemistry》《Chinese Chemical Letters》更多>>
相关基金：国家自然科学基金更多>>
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Affinity of anticancer drug,daunomycin,to core histones in solution:comparison of free and cross-linked proteins
《Acta Pharmacologica Sinica》2007年第5期731-737,共7页Azra RABBANI Sayeh ABDOSAMADI Naghmeh SARI-SARAF 
the research office of the University of Tehran to Azra RABBANI(№ 512-1-217)
Aim： The interaction of anthracycline anticancer drugs with chromatin, nucleosomes and histone H1 has been extensively studied. In the present study, for the first time, we have investigated the binding of anthracycl...
关键词：anthracycline antibiotics DAUNOMYCIN corehistones CHROMATIN fluorescence quenching 
Expression of Survivin in HL-60 Cells Treated with Chemotherapeutic Drugs
《The Chinese-German Journal of Clinical Oncology》2006年第3期213-215,共3页吴耀辉 邹萍 张敏 刘芳 陈建华 
This project was supported by a grant from the National Natural Sciences Foundation of China (No. 30370595).
Objective： To explore the relationship between survivin and drug resistance, and the changes of the survivin expression in HL-60 cells treated with three kinds of chemotherapeutic drugs. Methods： HL- 60 cells were t...
关键词：LEUKEMIA DAUNOMYCIN MITOXANTRONE arsenic trioxide SURVIVIN 
Study on the Interaction between Antitumor Drug Daunomycin and DNA
《Chinese Journal of Chemistry》2005年第5期576-580,共5页程圭芳 赵洁 徒永华 何品刚 方禹之 
Synthesis of Novel Spin Labeled Daunomycin Derivatives
《Chinese Chemical Letters》2001年第6期483-484,共2页Shu Jia ZHANG Yan Guang WANG Ju Biao LI 
Three spin labeled daunomycin derivatives 2-4 were synthesized and their biological activities were tested against mouse leukemia L1210 and human liver cancer BEL-7402 cells in vitro.
关键词：Spin labeled daunomycin derivatives antitumor activity SYNTHESIS 
THE EFFECT OF SEVERAL LEUKEMIA THERAPEUTIC DRUGS ON THE CALCIUM EQUILIBRIUM WITHIN THE K562 CELLS
《Chinese Journal of Cancer Research》1993年第4期58-61,共4页陆承荣 刘亚宁 王辉 
The Daunomycin, Cyclophosphamide, Cytarabine Hydrochloride and Vincrlstine Sulfale all are the drugs used in the therapy of leukemia. When the leukemia cell line, K562, were treated by them in vitro, a sharp decrease ...
关键词：DAUNOMYCIN Cyclophospamide Cytarablne Hydrochloride Vincristione sulfale LEUKEMIA CA2+ 
Tumor localization of anti-gastric cancer monoclonal antibody MGb_2-daunomycin conjugate in nude mice bearing human gastric carcinoma SGC-7901
《Journal of Medical Colleges of PLA(China)》1992年第1期81-83,共3页陈敏 黎松 邓敬兰 张学庸 陈希陶 
In the present study,an anti-gastric cancer monoclonal antibody MGb2-daunomycin（DM）conjugate was prepared by cis-aconitic anhydride method.The distribution of the conjugatein nude mice bearing human gastr...
关键词：stomach neoplasms antibodies monoclonal deunomycin antibody-toxin CONJUGATES iodine radioisotops mice NUDE 
一种由抗TF抗原的McAb和Daunomycin构建的免疫霉素在体外对人癌细胞的杀伤作用
《生物技术》1992年第1期22-25,共4页杜世彧 
在纯化了的抗TF(Thomsen—Friedenreich)抗原的McAb49H.8和抗肿瘤药物道诺霉素(Daunomyciu,DM)之间通过酸性敏感的顺式乌头酰基(Cis—Aconityl,CA)配接成免疫毒素49H.8—CA—DM.通过DNA合成抑制检测了此配接物在3个人癌细胞株(647V,EJ—...
关键词：免疫毒素 抗TF抗原McAb 抗肿瘤作用 
In vitro effects of monoclonal antibody targeted daunomycin on human gastric cancer cells
《Journal of Medical Colleges of PLA(China)》1991年第4期324-327,331,共5页汪森明 陈希陶 张学庸 樊代明 
In the present study,daunomydn （DIM） was chosen to conjugate cowdently with amonoclonal antitibody,MGb2,against human gastric cancer cells via a cis-aconitic anhydride linker（directly） or a dextmn brid...
关键词：STOMACH NEOPLASMS DAUNOMYCIN MONOCLONAL antibodies IMMUNOTOXIN targeting therapy 
POTENTIAL FOR TARGETING HEPATOMA WITH ANTI-FERRITIN IgG-DAUNOMYCIN IMMUNOCONJUGATE
《Chinese Journal of Cancer Research》1991年第3期37-41,共5页陈东泉 陈莉 仲伟强 王仁之 李希强 
Sheep anti-human ferritin IgG (AHFI) and nonspecific normal sheep IgG (NSIgG) were conjugated with Daunomycin (Dau) separately via a mediator Dextran T40. The conjugates (AHFI-Dex-Dau and NSIgG-Dex-Dau) were labelled ...
关键词：tumour targeting HEPATOMA chemo-immunocon jugate. 
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