supported by the National Key Research and Development Projects (2022YFC3602400);the National Natural Science Foundation of China (92249301,82200496);Project of National Clinical Research Center for Geriatric Diseases (NCRCGPLAGH-2022001)。
Atherosclerosis is the pathological cause of atherosclerotic cardiovascular disease(ASCVD),which rapidly progresses during the cellular senescence.Sodium-glucose cotransporter 2 inhibitors(SGLT2is)reduce major cardiov...
supported by grants from the National Key R&D Program of China(Grant No.2021YFC2500500);the National Natural Science Foundation of China(Grant No.82370444,82070464,82003741);the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB38010100);supported by the Program for Innovative Research Team of The First Affiliated Hospital of USTC(CXGG02);Anhui Provincial Key Research and Development Program(Grant No.202104j07020051);Anhui Provincial Natural Science Foundation(Grant No.2208085J08).
Urolithin A(UroA),a dietary phytochemical,is produced by gut bacteria from fruits rich in natural polyphenols ellagitannins(ETs).The efficiency of ETs metabolism to UroA in humans depends on gut microbiota.UroA has sh...
The lipid profile remains an important laboratory assessment to prevent cardiovascular disease. Interpretation of the non-fasting lipid profile has significantly changed based on new information concerning the pathoge...
Specifically Invited Professor of Oriental Scholar of Shanghai Colleges and Universities Tracking Program(No.GZ2016008);National Natural Science Foundation of China(No.81870347)
To the Editor:Atherosclerosis is the main pathological feature of ischemic stroke,which remains a major cause of disability and death worldwide.[1]Vulnerable plaque,was characterized by ulceration,platelet activation,...
supported by Shandong Taishan industry leading talent project(LJNY202101);the National Key R&D of China(2018YFC0311201)。
This study aimed to explore the effect of Bifidobacterium animalis F1-7 on the improvement of atherosclerotic inflammation.Arteriosclerosis model ApoE^(-/-)mice were orally administered with B.animalis F1-7 for 12 wee...
Lipid metabolism disorders would be among the components responsible for the risk of the onset of T2DM and its vascular complications. Apolipoprotein E plays an important role in lipid metabolism. We studied the invol...
the Capital Health Development Fund(201614035);CAMS Major Collaborative Innovation 517 Project(2016-12M-1-011)awarded to Dr.Jianjun Li.
Cardiovascular disease(CVD)is the leading cause of mortality worldwide.Multiple factors are involved in CVD,and emerging data indicate that lipoprotein(a)(Lp(a))may be associated with atherosclerotic cardiovascular di...
This study was supported by the Youth Fund of National Natural Science Foundation of China(No.82104081);Sichuan Province Science and Technology Support Program(No.2020JDRC0052);the 1.3.5 Project for Disciplines of excellence,West China Hospital,Sichuan University(No.ZYGD18020/ZYJC18006);Science and Technology Project of Xinjiang Production and Construction Corps(No.2022AB020).
Atherosclerosis is the main cause of ischemic stroke and myocardial infarction diseases.Nanoparticles have shown unique benefits for atherosclerosis treatment by targeting the lesional macrophages of plaques.However,m...
Objective:The effectiveness of statins in reducing atherosclerotic calcification remains controversial.The aim of this study was to confirm that simvastatin reduces atherosclerotic calcification and stabilizes plaque ...
To the Editor:The global prevalence of diabetes is increasing dramatically.[1]To prevent and treat diabetes and its cardiovascular complications,clinical practice guidelines recommend to assess the prevalent nonmodifi...