ACTOMYOSIN

作品数:11被引量:24H指数:2
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相关领域:医药卫生生物学更多>>
相关期刊:《医用生物力学》《CellBio》《Research》《Biophysics Reports》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Optimized pretreatment increases the susceptibility of hepatitis B virus infection by enhancing actomyosin-driven cell spreading
《hLife》2024年第4期201-205,共5页Shuzhi Cui Wei Gao Zonghong Li Yi Xu Yaming Jiu 
supported by the National Natural Science Foundation of China(32222022,92354301,92054104);Key Research and Development Program,Ministry of Science and Technology of China(2022YFC2303502,2021YFC2300204);Natural Science Foundation of Shanghai(23ZR1470900).
Hepatitis B virus(HBV),an enveloped DNA virus with a partially double-stranded DNA genome,causes transient and chronic hepatitis B in humans.A certain amount of chronic HBV infections eventually leads to liver cirrhos...
关键词:INFECTION BATCH eventually 
Microtubule Assists Actomyosin to Regulate Cell Nuclear Mechanics and Chromatin Accessibility被引量:5
《Research》2023年第3期619-631,共13页Jiwen Geng Zhefeng Kang Qian Sun Man Zhang Peng Wang Yupei Li Jiameng Li Baihai Su Qiang Wei 
the National Natural Science Foundation of China(Grant No.32000951,51973129);the Sichuan Science and Technology Program(Grant No.2022YFS0147);the Science and Technology Achievement Transformation Fund of West China Hospital of Sichuan University(Grant No.CGZH19006);the Med-X Innovation Programme of Med-X Center for Materials of Sichuan University(Grant No.MCM202101);the 1.3.5 project for disciplines of excellence from West China Hospital of Sichuan University(Grant No.ZYJC21010);Med+Biomaterial Institute of West China Hospital/West China School of Medicine of Sichuan University(Grant No.ZYME20001).
Cellular behaviors and functions can be regulated by mechanical cues from microenvironments,which are transmitted to nucleus through the physical connections of cytoskeletons in the cells.How these physical connection...
关键词:determination behaviors STIFF 
HBXIP blocks myosin-ⅡA assembly by phosphorylating and interacting with NMHC-ⅡA in breast cancer metastasis被引量:1
《Acta Pharmaceutica Sinica B》2023年第3期1053-1070,共18页Lu Zhang Xiaolei Zhou Bowen Liu Xuhe Shi Xianmeng Li Feifei Xu Xueli Fu Xue Wang Kai Ye Tianzhi Jin Huimin Sun Qianqian Li Weiying Zhang Lihong Ye 
supported by the grants from National Natural Science Foundation of China(82072929,82072943,and 31870752,China).
Tumor metastasis depends on the dynamic balance of the actomyosin cytoskeleton.As a key component of actomyosin filaments,non-muscle myosin-ⅡA disassembly contributes to tumor cell spreading and migration.However,its...
关键词:Breast cancer metastasis Actomyosin cytoskeleton HBXIP Myosin-IIA NMHC-IIA PHOSPHORYLATION PKCβII BEZAFIBRATE 
Hemodynamic Shear Stress Regulates the Survival of Circulating Tumour Cells Through Piezo1-Actomyosin-Mediated YAP/TAZ Nuclear Translocation
《医用生物力学》2019年第A01期130-131,共2页Keming Li Ying XIN Kai Tang Youhua Tan 
It is critical to combat tumor metastasis by eradicating disseminated tumor cells in any step during the metastasis process.After entering the blood circulation system,tumor cells are in suspension and experience cons...
关键词:HEMODYNAMIC Shear Stress CIRCULATING TUMOUR Cells YAP/TAZ Nuclear TRANSLOCATION TAZ 
Shear Stress Regulates Tumor Cell Mechanics and Actomyosin-Dependent Survival and Chemoresistance
《医用生物力学》2019年第A01期142-143,共2页Ying XIN Junfan WANG Kai TANG Youhua TAN 
the support from National Natural Science Foundation of China ( 11672255);Shenzhen Science and Technology Innovation Commission ( JCYJ20170303160515987, JCYJ20170413154735522 );Early Career Scheme from Research Grants Council of the Hong Kong Special Administrative Region,China ( PolyU 252094 /17E);the internal grant from the Hong Kong Polytechnic University ( 1-ZE4Q,1-ZVJ8)
Metastasis is the main cause of cancer death,and tumor cells mainly disseminate to the distal organs through the blood circulation,in which they experience considerable levels of fluid shear stress.CTCs are heterogene...
关键词:TUMOR Cell MECHANICS Actomyosin-Dependent SURVIVAL CHEMORESISTANCE 
Elongator controls cortical interneuron migration by regulating actomyosin dynamics
《Cell Research》2016年第10期1131-1148,共18页Sylvia Tielens Sandra Huysseune Juliette D Godin Alain Chariot Brigitte Malgrange Laurent Nguyen 
The migration of cortical interneurons is a fundamental process for the establishment of cortical connectivity and its impairment underlies several neurological disorders. During development, these neurons are born in...
关键词:cortical interneurons cerebral cortex .actomyosin COFILIN 
Thermodynamic aspects of ATP hydrolysis of actomyosin complex被引量:1
《Biophysics Reports》2016年第5期87-94,共8页Xuejun C. Zhang Wei Feng 
SUMMARY Directional movement of cellular components is essen- tial to all eukaryotic cells, and is driven by a mecha- noenzymatic system consisting largely of the actin- myosin cytoskeletal protein complex. Structural...
关键词:THERMODYNAMIC ACTOMYOSIN 
Induction of entosis by epithelial cadherin expression被引量:14
《Cell Research》2014年第11期1288-1298,共11页Qiang Sun Edmund S Cibas Hongyan Huang Louis Hodgson Michael Overholtzer 
Acknowledgments We thank Drs Alan Hall and Xuejun Jiang and their lab members, and members of the Overholtzer laboratory for reagents and discussions on the manuscript. We thank Drs Keith R Johnson, Klaus Hahn, Michael Sheetz, Erik Sahai, and Tingchao Chou for reagents. This work was supported by grants from the NCI (CA154649, MO), the NIGMS (GM09312, LH), the Geoffrey Beene Cancer Research Center at MSKCC (MO), the Louis V Gerstner, Jr Young Investigators Fund (MO), the Benjamin Friedman Research Fund (MO), the National Basic Research Program of China (2015CB553704, QS), and the National Natural Science Foundation of China (30871364 and 81472588, QS).
Cell engulfment typically targets dead or dying cells for clearance from metazoan tissues. However, recent evidence demonstrates that live cells can also be targeted and that engulfment can cause cell death. Entosis i...
关键词:entosis CADHERIN Rho GTPase ACTOMYOSIN p190A RhoGAP tumor suppression 
Wound Closure on the Neonatal Rat Skin II. The Potential Ability of Epidermis to Close Small-Sized Wounds Independently of the Underlying Dermis
《CellBio》2013年第4期257-266,共10页Mary Arai Takashi Matsuzaki Setsunosuke Ihara 
Reepithelialization of skin which comprises epidermis and dermis has not been fully elucidated due to the complexity of the participants as well as the interactions therein. In this study, the intrinsic roles and beha...
关键词:Wound Closure Reepithelialization Rat Neonate EPIDERMIS Migration ACTOMYOSIN Rho Family SMALL GTPASES 
Interaction of non-adherent suspended neutrophils to complement opsonized pathogens: a new assay using optical traps被引量:1
《Cell Research》2006年第11期887-894,共8页TomokoSUZUki MasaruYanai HiroshiKubo AkiOKanda HidetadaSasaki James P Butler 
Phagocytosis of opsonized pathogens by circulating non-adherent neutrophils is an essential step in host defense, which when overwhelmed contributes to sepsis. To investigate the role played by ligation of complement ...
关键词:neutrophil PHAGOCYTOSIS pseudopod formation ACTOMYOSIN COMPLEMENT CR3/4 receptor 
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