Uridine diphosphate-dependent glycosyltransferases(UGTs)mediate the glycosylation of plant metabolites,thereby altering their physicochemical properties and bioactivities.Plants possess numerous UGT genes,with the enc...
Cancer is considered a leading cause of death worldwide due to its high morbidity and mortality rate.Conventional treatments for cancer therapy,such as chemotherapy,and radiotherapy,have been hampered by their side ef...
Objective:The objective of the study was to identify Nrf2 activators from differently treated Morinda citrifolia L.fruit juices and their cytotoxicity.Materials and Methods:Noni fruit juices were prepared by different...
Background:Chinese Danggui(Angelica sinensis)and Japanese Danggui(Angelica acutiloba)are evaluated as the same in using and critical of quality control in Vietnamese Pharmacopoeia.In Vietnam,Japanese Danggui were accl...
Supported by Education Department of Sichuan Province(14ZA0152);Health Department of Sichuan Province(130279)
[Objectives] This study was conducted to investigate the effect of scopoletin on the growth of breast cancer cell lines.[Methods] Cell culture,light microscopy and MTT assay for measuring cell viability were used to c...
Supported by Education Department of Sichuan Province(14ZA0152);Health Department of Sichuan Province(130279)
[Objectives]This study was conducted to investigate the effect of scopoletin on the proliferation of breast cancer cell lines.[Methods]Cell viability,gene expression and cell cycle were measured by cell culture,RT-PCR...
Acknowledgements This work was funded by the National S&T Major Project of China (No 2011ZX09310-002) and the National Natural Science Foundation of China (No 81130060).
Scopoletin is an active coumarin possessing a variety of pharmacological activities, including anti-hyperuricemic effect, but with poor solubility. To improve its oral bioavailability, we attempted to encapsulate scop...
supported by the National Natural Science Foundation of China (No.81573682 and No.81102752);the Beijing Natural Science Foundation (No.2112010)
Objective:To explore the effects of arteannuin B,arteannuic acid and scopoletin on the pharmacokinetics of artemisinin in mice.Methods:Artemisinin and a combination of artemisinin,arteannuin B,arteannuic acid and scop...
Supported by National Natural Science Foundation of China(31272058);Specialized Research Fund for the Doctoral Program of Higher Education(20100182120021)
[Objective] This study aimed to investigate the acaricidal lffect of scopo- letin, and provide the biochemical evidences of scopoletin influencus Ca2+-ATPase activity and gene expressions in the Carmine Spider Mite, ...
Artemisinin,a constituent of Artemisia annua L.,is a well-known antimalarial drug.Artemisinin-type drugs also inhibit cancer growth in vitro and in vivo.Herbal extracts of A.annua inhibit the growth of cancer cell lin...