SCOPOLETIN

作品数:16被引量:39H指数:4
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相关领域:医药卫生更多>>
相关作者:张亮刘雪莉刘辉林琎梁元存更多>>
相关机构:中国药科大学浙江省医学科学院中国科学院大学中国科学院更多>>
相关期刊:《浙江省医学科学院学报》《Asian Pacific Journal of Tropical Biomedicine》《Acta Pharmacologica Sinica》《中国农业科学》更多>>
相关基金:国家自然科学基金北京市自然科学基金国家教育部博士点基金更多>>
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Subfunctionalization of a monolignol to a phytoalexin glucosyltransferase is accompanied by substrate inhibition
《Plant Communications》2023年第3期151-170,共20页Jieren Liao Guangxin Sun Elisabeth Kurze Wieland Steinchen Timothy D.Hoffmann Chuankui Song Zhiwei Zou Thomas Hoffmann Wilfried G.Schwab 
DFG SCHW 634/34-1.
Uridine diphosphate-dependent glycosyltransferases(UGTs)mediate the glycosylation of plant metabolites,thereby altering their physicochemical properties and bioactivities.Plants possess numerous UGT genes,with the enc...
关键词:GLYCOSYLTRANSFERASE substrate inhibition hydrogen/deuterium exchange mass spectrometry protein morphing protein conformer SCOPOLETIN 
Scopoletin: Anticancer potential and mechanism of action被引量:1
《Asian Pacific Journal of Tropical Biomedicine》2023年第1期1-8,共8页Lia Meilawati Rita Marleta Dewi Aprilia Nur Tasfiyati Abdi Wira Septama Lucia Dwi Antika 
Cancer is considered a leading cause of death worldwide due to its high morbidity and mortality rate.Conventional treatments for cancer therapy,such as chemotherapy,and radiotherapy,have been hampered by their side ef...
关键词:SCOPOLETIN COUMARIN ANTICANCER Signaling pathway Cell cycle arrest APOPTOSIS 
Nrf2 Activation by Morinda citrifolia L. (Noni) Fruit Juices
《World Journal of Traditional Chinese Medicine》2021年第2期184-191,共8页Arulmani Manavalan Mallique Qader Xiaohua Wu Shugeng Cao 
Objective:The objective of the study was to identify Nrf2 activators from differently treated Morinda citrifolia L.fruit juices and their cytotoxicity.Materials and Methods:Noni fruit juices were prepared by different...
关键词:HPLC noni fruit NRF2 nuclear factor kappa B SCOPOLETIN 
Simultaneous Quantitative Analysis of Five Components in Angelica sinensis and Angelica acutiloba Acclimatized Growing in Vietnam by High-Performance Liquid Chromatography with Photodiode Array Detector
《World Journal of Traditional Chinese Medicine》2021年第1期6-10,共5页Thi Minh Tam Pham Thi Thu Cuc Le Van Thanh Nguyen Viet Hung Tran 
Background:Chinese Danggui(Angelica sinensis)and Japanese Danggui(Angelica acutiloba)are evaluated as the same in using and critical of quality control in Vietnamese Pharmacopoeia.In Vietnam,Japanese Danggui were accl...
关键词:Chlorogenic acid Danggui ferulic acid LIGUSTILIDE SCOPOLETIN XANTHOTOXIN 
Mechanism of Apoptosis Induced by Scopoletin in Breast Cancer Cells被引量:2
《Agricultural Biotechnology》2019年第5期145-147,共3页Xiaoyan LIU Juan LI Chenggang DUAN Zhiqiang MEI 
Supported by Education Department of Sichuan Province(14ZA0152);Health Department of Sichuan Province(130279)
[Objectives] This study was conducted to investigate the effect of scopoletin on the growth of breast cancer cell lines.[Methods] Cell culture,light microscopy and MTT assay for measuring cell viability were used to c...
关键词:SCOPOLETIN BREAST CANCER APOPTOSIS 
Study on the Inhibitory Effect of Scopoletin on Proliferation and Metastasis of Breast Cancer Cells
《Agricultural Biotechnology》2019年第4期110-112,122,共4页Xiaoyan LIU Juan LI Zhiqiang MEI 
Supported by Education Department of Sichuan Province(14ZA0152);Health Department of Sichuan Province(130279)
[Objectives]This study was conducted to investigate the effect of scopoletin on the proliferation of breast cancer cell lines.[Methods]Cell viability,gene expression and cell cycle were measured by cell culture,RT-PCR...
关键词:SCOPOLETIN BREAST cancer Inhibition STUDY 
Soluplus micelles for improving the oral bioavailability of scopoletin and their hypouricemic effect in vivo被引量:5
《Acta Pharmacologica Sinica》2017年第3期424-433,共10页Ying-chun ZENG Sha LI Chang LIU Tao GONG Xun SUN Yao FU Zhi-rong ZHANG 
Acknowledgements This work was funded by the National S&T Major Project of China (No 2011ZX09310-002) and the National Natural Science Foundation of China (No 81130060).
Scopoletin is an active coumarin possessing a variety of pharmacological activities, including anti-hyperuricemic effect, but with poor solubility. To improve its oral bioavailability, we attempted to encapsulate scop...
关键词:SCOPOLETIN Soluplus micelles oral bioavailability PHARMACOKINETICS tissue distribution hyperuricemic mice 
Effects of arteannuin B,arteannuic acid and scopoletin on pharmacokinetics of artemisinin in mice被引量:1
《Asian Pacific Journal of Tropical Medicine》2016年第7期648-652,共5页Chao Zhang Mu-Xin Gong Feng Qiu Jing Li Man-Yuan Wang 
supported by the National Natural Science Foundation of China (No.81573682 and No.81102752);the Beijing Natural Science Foundation (No.2112010)
Objective:To explore the effects of arteannuin B,arteannuic acid and scopoletin on the pharmacokinetics of artemisinin in mice.Methods:Artemisinin and a combination of artemisinin,arteannuin B,arteannuic acid and scop...
关键词:ARTEMISININ Arteannuin B Arteannuic ACID SCOPOLETIN PHARMACOKINETICS 
Biochemical Evidences for Scopoletin Inhibits Ca^(2+)-ATPase Activity in the Carmine Spider Mite,Tetranychus cinnabarinus(Boisduval)
《Agricultural Science & Technology》2015年第4期826-831,共6页Qiuli HOU Dan WANG Bingchuan ZHANG Wei DING Yongqiang ZHANG 
Supported by National Natural Science Foundation of China(31272058);Specialized Research Fund for the Doctoral Program of Higher Education(20100182120021)
[Objective] This study aimed to investigate the acaricidal lffect of scopo- letin, and provide the biochemical evidences of scopoletin influencus Ca2+-ATPase activity and gene expressions in the Carmine Spider Mite, ...
关键词:SCOPOLETIN Ca2+-ATPase INHIBITION Tetranychus cinnabarinus Acaricidal 
Treatment of Iron-Loaded Veterinary Sarcoma by Artemisia annua被引量:4
《Natural Products and Bioprospecting》2014年第2期113-118,共6页Elmar Breuer Thomas Efferth 
Artemisinin,a constituent of Artemisia annua L.,is a well-known antimalarial drug.Artemisinin-type drugs also inhibit cancer growth in vitro and in vivo.Herbal extracts of A.annua inhibit the growth of cancer cell lin...
关键词:ARTEMISININ Asteraceae SCOPOLETIN Veterinary cancer Comparative oncology 
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