supported by the National Research Foundation(NRF)S&F-Scarce Skills Postdoctoral Fellowship,No.120752(to AC);the Global Excellence and Stature,Fourth Industrial Revolution(GES 4.0)Postgraduate Scholarship(to MJR);the South African Research Chairs Initiative of the Department of Science and Technology and National Research Foundation of South Africa(SARChI/NRF-DST),No.146290(to DDS and HA).
Photobiomodulation,originally used red and near-infrared lasers,can alter cellular metabolism.It has been demonstrated that the visible spectrum at 451-540 nm does not necessarily increase cell proliferation,near-infr...
Skin cancer,a prevalent malignancy worldwide,poses significant health concerns owing to its increasing incidence.Autophagy,a natural cellular process,is a pivotal event in skin cancer and has advantageous and detrimen...
supported by the National Key Research and Development Program of China(Grant No.2022YFA1303900 to S.Y.);the National Natural Science Foundation of China(Grant Nos.32270921 and 82070567 to S.Y.,and 82204354 to Y.H.);the Open Project of State Key Laboratory of Reproductive Medicine of Nanjing Medical University(Grant No.SKLRM-2021B3 to S.Y.)'the Talent Cultivation Project of"Organized Scientific Research"of Nanjing Medical University(Grant No.NJMURC20220014 to S.Y.);the Natural Science Foundation of Jiangsu Province(Grant No.BK20221352 to B.W.);the Jiangsu Provincial Outstanding Postdoctoral Program(Grant No.2022ZB419 to Y.H.);the Postdoctoral Research Funding Project of Gusu School(Grant No.GSBSHKY202104 to Y.H.);the China Postdoctoral Science Foundation(Grant No.2023T160329 to Y.H.).
Ferroptosis is a pattern of iron-mediated regulatory cell death characterized by oxidative damage.The molecular regulatory mechanisms are related to iron metabolism,lipid peroxidation,and glutathione metabolism.Additi...
Bayesian estimation is applied to the analysis of backflow vortex instabilities in typical three-and four bladed liquid propellant rocket(LPR)engine inducers.The flow in the impeller eye is modeled as a set of equally...
supported by the Fundamental Research Funds for the Central Universities(No.SWU-KQ22024);the NMPA Key Laboratory for Research and Evaluation of Pharmaceutical Preparation and Excipients(No.PPE2023005);the China Postdoctoral Science Foundation(No.2023M740731);the Chongqing Science and Technology Commission(No.CSTB2022TIAD-KPX0094);National Key Research and Development Program of China(No.2021YFD1800900);National Natural Science Foundation of China(No.82073790).
Liver fibrosis is characterized by the excessive accumulation of extracellular matrix(ECM),which is primarily produced by activated hepatic stellate cells(HSCs).However,effective therapies for hepatic fibrosis are cur...
Pyroptosis is a newly identified form of regulated cell death driven by pathogen-associated molecular patterns(PAMPs),environment-or host-derived damage-associated molecular patterns(DAMPs),gram-negative bacteria,and ...
National Natural Science Foundation of China(No.82073108)
Lung cancer is one of the most common malignancies and has the highest number of deaths among all cancers.Despite continuous advances in medical strategies,the overall survival of lung cancer patients is still low,pro...
This research was funded by the Intramural Research Program of the National Institutes of Health,the National Cancer Institute.
Aim:Ferroptosis is a non-apoptotic form of cell death caused by lethal lipid peroxidation.Several small molecule ferroptosis inducers(FINs)have been reported,yet little information is available regarding their interac...
supported by the National Key R&D Plan of China(2018YFA0107802)(to X-JS);the National Natural Science Foundation of China(NSFC)General Program(No.81670094 and 81470316)(to X-JS);the Shanghai Municipal Education Commission-Gaofeng Clinical Medicine(China)(No.20152506)(to X-JS);Shanghai Collaborative Innovation Program on Regenerative Medicine and Stem Cell Research(China)(No.2019CXJQ01)(to S-JC and X-JS);the Samuel Waxman Cancer Research Foundation,and the Shanghai Guangci Translational Medical Research Development Foundation;X-JS was supported by the 1000 Talents Program for Young Scholars(China).
Ferroptosis is a form of regulated cell death characterized by iron-dependent overaccumulation of lipid peroxides,which causes membrane damage and cell lysis.Ferroptosis can be prevented by cellular antioxidant mechan...
Objective:To investigate the interaction of p53 with docetaxel and berberine and their anticancer activities against oral squamous cell carcinoma.Methods:The interaction between p53 with docetaxel and berberine was in...