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作品数:40被引量:118H指数:7
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相关领域:医药卫生更多>>
相关作者:罗晓艳唐巍更多>>
相关机构:北卡罗来纳大学北卡罗来纳州立大学更多>>
相关期刊:《Chinese Medical Journal》《Journal of Animal Science and Biotechnology》《Journal of Earth Science and Engineering》《Acta Pharmacologica Sinica》更多>>
相关基金:国家自然科学基金中国博士后科学基金国家重点基础研究发展计划北京市自然科学基金更多>>
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Photobiomodulation:a novel approach to promote trans-differentiation of adipose-derived stem cells into neuronal-like cells
《Neural Regeneration Research》2025年第2期598-608,共11页Daniella Da Silva Madeleen Jansen van Rensburg Anine Crous Heidi Abrahamse 
supported by the National Research Foundation(NRF)S&F-Scarce Skills Postdoctoral Fellowship,No.120752(to AC);the Global Excellence and Stature,Fourth Industrial Revolution(GES 4.0)Postgraduate Scholarship(to MJR);the South African Research Chairs Initiative of the Department of Science and Technology and National Research Foundation of South Africa(SARChI/NRF-DST),No.146290(to DDS and HA).
Photobiomodulation,originally used red and near-infrared lasers,can alter cellular metabolism.It has been demonstrated that the visible spectrum at 451-540 nm does not necessarily increase cell proliferation,near-infr...
关键词:differentiation inducers green photobiomodulation immortalized adipose-derived stem cell near-infrared photobiomodulation neurodegenerative disease NEUROGENESIS PHOTOBIOMODULATION TRANS-DIFFERENTIATION 
Autophagy as a targeted therapeutic approach for skin cancer:Evaluating natural and synthetic molecular interventions
《Cancer Pathogenesis and Therapy》2024年第4期231-245,共15页Md.Liakot Ali Amdad Hossain Roky S.M.Asadul Karim Azad Abdul Halim Shaikat Jannatul Naima Meem Emtiajul Hoque Abu Mohammed Fuad Ahasan Mohammed Murshedul Islam Md.Saifur Rahaman Arif Md.Saqline Mostaq Md.Zihad Mahmud Mohammad Nurul Amin MdAshiq Mahmud 
Skin cancer,a prevalent malignancy worldwide,poses significant health concerns owing to its increasing incidence.Autophagy,a natural cellular process,is a pivotal event in skin cancer and has advantageous and detrimen...
关键词:AUTOPHAGY Skin cancer Autophagy inducers Autophagy inhibitors Nature-derived compounds Synthetic compounds 
Ferroptosis:Iron-mediated cell death linked to disease pathogenesis
《Journal of Biomedical Research》2024年第5期413-435,共23页Xiangyu Zhang Yingchao Hu Bingwei Wang Shuo Yang 
supported by the National Key Research and Development Program of China(Grant No.2022YFA1303900 to S.Y.);the National Natural Science Foundation of China(Grant Nos.32270921 and 82070567 to S.Y.,and 82204354 to Y.H.);the Open Project of State Key Laboratory of Reproductive Medicine of Nanjing Medical University(Grant No.SKLRM-2021B3 to S.Y.)'the Talent Cultivation Project of"Organized Scientific Research"of Nanjing Medical University(Grant No.NJMURC20220014 to S.Y.);the Natural Science Foundation of Jiangsu Province(Grant No.BK20221352 to B.W.);the Jiangsu Provincial Outstanding Postdoctoral Program(Grant No.2022ZB419 to Y.H.);the Postdoctoral Research Funding Project of Gusu School(Grant No.GSBSHKY202104 to Y.H.);the China Postdoctoral Science Foundation(Grant No.2023T160329 to Y.H.).
Ferroptosis is a pattern of iron-mediated regulatory cell death characterized by oxidative damage.The molecular regulatory mechanisms are related to iron metabolism,lipid peroxidation,and glutathione metabolism.Additi...
关键词:ferroptosis lipid peroxidation molecular regulatory mechanisms ferroptosis-related diseases ferroptosis inducers ferroptosis inhibitors 
Identification of Backflow Vortex Instability in Rocket Engine Inducers
《风机技术》2024年第5期7-18,共12页Luca d’Agostino 
Bayesian estimation is applied to the analysis of backflow vortex instabilities in typical three-and four bladed liquid propellant rocket(LPR)engine inducers.The flow in the impeller eye is modeled as a set of equally...
关键词:Aerospace Propulsion Liquid Propellant Rockets LPR Feed Turbopumps Turbopump Flow Instabilities BackflowVortex Instability Bayesian Parametric Identification 
Oral delivery of ferroptosis inducers for effective treatment of hepatic fibrosis
《Nano Research》2024年第8期7621-7630,共10页Yinglan Yu Shunlong Zhang Yongfeng Xu Hao Shao Lei Luo 
supported by the Fundamental Research Funds for the Central Universities(No.SWU-KQ22024);the NMPA Key Laboratory for Research and Evaluation of Pharmaceutical Preparation and Excipients(No.PPE2023005);the China Postdoctoral Science Foundation(No.2023M740731);the Chongqing Science and Technology Commission(No.CSTB2022TIAD-KPX0094);National Key Research and Development Program of China(No.2021YFD1800900);National Natural Science Foundation of China(No.82073790).
Liver fibrosis is characterized by the excessive accumulation of extracellular matrix(ECM),which is primarily produced by activated hepatic stellate cells(HSCs).However,effective therapies for hepatic fibrosis are cur...
关键词:liver fibrosis hepatic stellate cells oral delivery intestinal epithelium ferroptosis 
Recent progress in pyroptosis probes and inducers
《Advanced Sensor and Energy Materials》2024年第2期41-59,共19页Aijing Zhang Jianguo Zheng Xin Qin Nengwang Yu Kang-Nan Wang 
Pyroptosis is a newly identified form of regulated cell death driven by pathogen-associated molecular patterns(PAMPs),environment-or host-derived damage-associated molecular patterns(DAMPs),gram-negative bacteria,and ...
关键词:PYROPTOSIS Fluorescent probe Cancer therapy Cell death NANOMATERIALS 
Emerging mechanisms of ferroptosis and its implications in lung cancer被引量:1
《Chinese Medical Journal》2024年第7期818-829,共12页Qian Li Qibin Song Huadong Pei Yali Chen 
National Natural Science Foundation of China(No.82073108)
Lung cancer is one of the most common malignancies and has the highest number of deaths among all cancers.Despite continuous advances in medical strategies,the overall survival of lung cancer patients is still low,pro...
关键词:Lung cancer Ferroptosis Ferroptosis regulators Ferroptosis inducers Cancer treatment 
The multidrug resistance transporter P-glycoprotein confers resistance to ferroptosis inducers
《Cancer Drug Resistance》2023年第3期468-480,共13页William J.E.Frye Lyn M.Huff JoséM.González Dalmasy Paula Salazar Rachel M.Carter Ryan T.Gensler Dominic Esposito Robert W.Robey Suresh V.Ambudkar Michael M.Gottesman 
This research was funded by the Intramural Research Program of the National Institutes of Health,the National Cancer Institute.
Aim:Ferroptosis is a non-apoptotic form of cell death caused by lethal lipid peroxidation.Several small molecule ferroptosis inducers(FINs)have been reported,yet little information is available regarding their interac...
关键词:Ferroptosis drug resistance P-GLYCOPROTEIN ABCG2 
The LIFR-targeting small molecules EC330/EC359 are potent ferroptosis inducers
《Genes & Diseases》2023年第3期735-738,共4页Chang-Zhou Feng Ning-Zhe Li Xi-Bo Hu Yin-Yin Xie Qiu-Hua Huang Jianming Zhang Zhu Chen Sai-Juan Chen Fudi Wang Xiao-Jian Sun 
supported by the National Key R&D Plan of China(2018YFA0107802)(to X-JS);the National Natural Science Foundation of China(NSFC)General Program(No.81670094 and 81470316)(to X-JS);the Shanghai Municipal Education Commission-Gaofeng Clinical Medicine(China)(No.20152506)(to X-JS);Shanghai Collaborative Innovation Program on Regenerative Medicine and Stem Cell Research(China)(No.2019CXJQ01)(to S-JC and X-JS);the Samuel Waxman Cancer Research Foundation,and the Shanghai Guangci Translational Medical Research Development Foundation;X-JS was supported by the 1000 Talents Program for Young Scholars(China).
Ferroptosis is a form of regulated cell death characterized by iron-dependent overaccumulation of lipid peroxides,which causes membrane damage and cell lysis.Ferroptosis can be prevented by cellular antioxidant mechan...
关键词:SYSTEM initially LIMITING 
In-silico and in-vitro evaluation of docetaxel and berberine as potential p53 modulating apoptotic inducers in oral squamous cell carcinoma被引量:1
《Asian Pacific Journal of Tropical Biomedicine》2022年第12期530-540,共11页Smrutipragnya Samal Rajesh Kumar Meher Debasmita Dubey Showkat Ahmad Mir Binata Nayak Mahesh Chandra Sahu Pradeep Kumar Naik Goutam Rath Santosh Kumar Swain 
Objective:To investigate the interaction of p53 with docetaxel and berberine and their anticancer activities against oral squamous cell carcinoma.Methods:The interaction between p53 with docetaxel and berberine was in...
关键词:DOCETAXEL BERBERINE PC-3 OVCAR-3 OSCC SCC-29B P53 Anticancer Apoptosis 
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