云南高校图书馆联盟文献共享服务平台- PSEUDOURIDINE

PSEUDOURIDINE: 作品数：10被引量：30H指数：4; 导出分析报告; 相关领域：生物学医药卫生更多>>; 相关作者：赵新生高毅勤更多>>; 相关机构：北京分子科学国家实验室北京大学更多>>; 相关期刊：《World Journal of Biological Chemistry》《The Crop Journal》《Fundamental Research》《Chinese Medical Journal》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划更多>>

OsPPG encodes a pseudouridine-5'-phosphate glycosidase and regulates rice spikelet development: 《The Crop Journal》2024年第3期698-708,共11页Rui Chen Dagang Tian Yarong Lin Jiaqing Huang Qinqin Yang Yupei Li Huaqing Liu Shaohua Yang Jingyang Chen Shufen Zhou Feng Wang Shubiao Zhang; partially supported by the Key Program of the National Natural Science of Fujian Province(2022J02010);Science and Technology Project of State Administration of Science,Technology and Industry for National Defense,Seed Innovation and Industrialization Project of Fujian Province(zycxny2021003);Fujian Province Public Welfare Scientific Research Program(2016R1018-8)。; Florets are the basic structural units of spikelets,and their morphogenesis determines the yield and quality of rice grains.However,whether and how pseudouridine-5’-phosphate glycosidase participates in rice spikelet...; 关键词：OsPPG Reproductive regulation Spikelet development RICE

A novel deep generative model for mRNA vaccine development: Designing 5′ UTRs with N1-methyl-pseudouridine modification被引量：2: 《Acta Pharmaceutica Sinica B》2024年第4期1814-1826,共13页Xiaoshan Tang Miaozhe Huo Yuting Chen Hai Huang Shugang Qin Jiaqi Luo Zeyi Qin Xin Jiang Yongmei Liu Xing Duan Ruohan Wang Lingxi Chen Hao Li Na Fan Zhongshan He Xi He Bairong Shen Shuai Cheng Li Xiangrong Song; This work was financially supported by the Postdoctoral Research Foundation of National Key S&T Special Projects(2018ZX09201018-024,China);Sichuan Province Science and Technology Support Program(2022YFH0001 and 2021YFH0003,China).; Efficient translation mediated by the 5'untranslated region(5'UTR)is essential for the robust efficacy of mRNA vaccines.However,the N1-methyl-pseudouridine(m1)modification of mRNA can impact the translation efficiency...; 关键词：mRNA vaccine Machine learning 5'UTR mRNA design Sequence design N1-Methyl-pseudouridine COVID-19 SARS-CoV-2

Sequencing methods and functional decoding of mRNA modifications被引量：1: 《Fundamental Research》2023年第5期738-748,共11页Kai Li Jinying Peng Chengqi Yi; the Ministry of Science and Technology of China(2019YFA0110902,2019YFA0802201)。; More than 160 types of post-transcriptional RNA modifications have been reported;there is substantial variation in modification type,abundance,site,and function across species,tissues,and RNA type.The recent developme...; 关键词：RNA modification N6 2′-O-dimethyladenosine(m6Am) N1-methyladenosine(m1A) 5-Methylcytosine(m5C) N6-methyladenosine(m6A) Pseudouridine(Ψ) Inosine(I)

Role of main RNA modifications in cancer:N^(6)-methyladenosine,5-methylcytosine,and pseudouridine被引量：9: 《Signal Transduction and Targeted Therapy》2022年第5期1555-1585,共31页Chen Xue Qingfei Chu Qiuxian Zheng Shiman Jiang Zhengyi Bao Yuanshuai Su Juan Lu Lanjuan Li; This work was funded by the National Key Research and Development Program of China(2021YFC2301800);the National Nature Science Foundation of China(U20A20343);Zhejiang University Academic Award for Outstanding Doctoral Candidates(2020055).; Cancer is one of the major diseases threatening human life and health worldwide.Epigenetic modification refers to heritable changes in the genetic material without any changes in the nucleic acid sequence and results ...; 关键词：DISEASES CANCER CANCER

Epitranscriptomics of cancer被引量：2: 《World Journal of Clinical Oncology》2018年第3期42-55,共14页Marina Tusup Thomas Kundig Steve Pascolo; Supported by University of Zurich:"URPP:Translational Cancer research";the"MERIT"project supported by the FP7 European Union’s Research;Innovation Funding program; The functional impact of modifications of cellular RNAs,including m RNAs,mi RNAs and lnc RNAs,is a field of intense study.The role of such modifications in cancer has started to be elucidated.Diverse and sometimes opp...; 关键词：RNA modifications N6-methyladenosine 5-methylcytidine 2’O-methylation or methylcytidine PSEUDOURIDINE INOSINE

Deciphering the epitranscriptome： A green perspective被引量：5: 《Journal of Integrative Plant Biology》2016年第10期822-835,共14页Alice Burgess; supported by ARC grants DP110103805 and FT13100525 awarded to I.S.and an APA and a GRDC PhD topup scholarship awarded to A.B.; The advent of high-throughput sequencing technol- ogies coupled with new detection methods of RNA modifica- tions has enabled investigation of a new layer of gene regulation - the epitranscriptome. With over loo known...; 关键词：RNA modifications epitranscriptome RNA 5-methylcytosine （m^5C） N^6-methyladenosine （m^6A） Pseudouridine （φ） ARABIDOPSIS

Pseudouridine in a new era of RNA modifications被引量：4: 《Cell Research》2015年第2期153-154,共2页Boxuan Simen Zhao Chuan He; Two articles recently published in Nature and Cell report the first transcriptome-wide maps of pseudouridine （ψ） at single-base reso- lution through selective chemical labeling, suggesting new mechanisms and functi...; 关键词：非编码RNA 尿嘧啶修改全基因组 MRNA 分辨率单碱基细胞

Insight into the mechanisms and functions of spliceosomal snRNA pseudouridylation被引量：1: 《World Journal of Biological Chemistry》2014年第4期398-408,共11页Hironori Adachi Yi-Tao Yu; Supported by Grants from the National Institute of Health to YiTao Yu,No.GM104077 and AG39559;by the University of Rochester CTSA award(to Yi-Tao Yu)from the National Center for Advancing Translational Sciences of the National Institute of Health,No.UL1TR000042; Pseudouridines(Ψs) are the most abundant and highly conserved modified nucleotides found in various stable RNAs of all organisms. Most Ψs are clustered in regions that are functionally important for pre-m RNA splici...; 关键词：Pre-m RNA SPLICING U2 sn RNA Box H/ACA RIBONUCLEOPROTEIN PSEUDOURIDINE Induced RNA modification

Pseudouridines in spliceosomal snRNAs被引量：6: 《Protein & Cell》2011年第9期712-725,共14页Andrew T.Yu Junhui Ge Yi-Tao Yu; Spliceosomal RNAs are a family of small nuclear RNAs(snRNAs)that are essential for pre-mRNA splicing.All vertebrate spliceosomal snRNAs are extensively pseudouridylated after transcription.Pseudouridines in spliceosom...; 关键词：small nuclear RNAs(snRNAs) PSEUDOURIDINE SPLICEOSOME small nuclear ribonucleoproteins(snRNPs)

CLINICAL VALUE OF URINARY AND SERUM PSEUDOURIDINE IN DIAGNOSIS AND MONITORING OF PRIMARY LIVER CANCER被引量：1: 《Chinese Medical Journal》1995年第3期46-50,共5页屠振兴许圣献吴孟超; Urinary and serum pseudouridine concentrations were determined by high-performance liquid chromatography in 80 patients with primary liver cancer, 32 with benign space occupying lesions of the liver, 42 with liver cir...; 关键词：CLINICAL VALUE OF URINARY AND SERUM PSEUDOURIDINE IN DIAGNOSIS AND MONITORING OF PRIMARY LIVER CANCER than

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