相关期刊:《World Journal of Biological Chemistry》《Journal of Pharmaceutical Analysis》《Acta Biochimica et Biophysica Sinica》《Science China(Life Sciences)》更多>>
supported by the National Natural Science Foundation of China(Grant Nos.:82025007,81930020,and 82170874);China Postdoctoral Science Foundation(Grant No.:2022M710099).
Excessive N-acetyl-p-benzoquinone imine(NAPQI)formation is a starting event that triggers oxidative stress and subsequent hepatocyte necrosis in acetaminophen(APAP)overdose caused acute liver failure(ALF).S-glutathion...
supported by the National Natural Science Foundation of China(31701216,31771542,31900502);the Natural Science Foundation of Shandong Province(ZR2017MC008)。
Cytoskeletal proteins are susceptible to glutathionylation under oxidizing conditions,and oxidative damage has been implicated in several neurodegenerative diseases.End-binding protein 1(EB1)is a master regulator of m...
Supported by the USA-Israel Binational Science Foundation,No.2013034;the Israel Science Foundation administered by the Israel Academy of Science,No.1235/17;the Jacki and Bruce Barron Cancer Research Scholars’Program;City of Hope and the Israel Cancer Research Fund,No.87735611.
The mammalian protein kinase C-interacting cousin of thioredoxin(PICOT;also termed glutaredoxin 3)is a multi-domain monothiol glutaredoxin that is involved in a wide variety of signaling pathways and biological proces...
We thank Dr.Barbara Valent for supplying pBV579(35S::mCherry::NLS::Tnos);This research was supported by the Kansas State University AES project NAHF381121(to S.H.P.,Q.W.,S.A.S.);National Science Foundation award IOS-1258028(F.F.W.,Y.H.,J.P.).
Chilling stress is a production constraint of tomato,a tropical origin,chilling-sensitive horticultural crop.The development of chilling tolerant tomato thus has significant potential to impact tomato production.Gluta...
Supported by The Swedish Research Council Medicine,No.3529;The Swedish Cancer Society,No.961;The Wallenberg Foundation
Ribonucleotide reductase(RNR), the rate-limitingenzyme in DNA synthesis, catalyzes reduction of thedifferent ribonucleotides to their corresponding deoxyri-bonucleotides. The crucial role of RNR in DNA synthesishas ma...
A functional relationship between monothiol glutaredoxins and BolAs has been unraveled by genomic analyses and in several high-throughput studies. Phylogenetic analyses coupled to transient expression of green fluo- r...
supported by grants from Minis-try of Science and Technology of China(Nos.2012CB910703 and 2006DFA31210);National Natural Science Foundation of China(Grant No.30570353)to BX;the ANR Grant(No.2010BLAN1616)to NR and JPJ.
Holo glutaredoxin(Grx)is a homo-dimer that bridges a[2Fe-2S]cluster with two glutathione(GSH)ligands.In this study,both monothiol and dithiol holo Grxs are found capable of transferring their iron-sulfur(FeS)cluster t...
Methionine sulfoxide reductases A and B (MsrA and MsrB) have been known to be thioredoxin (Trx)-depend- ent enzymes that catalyze the reduction of methionine sulfoxide in a stereospecific manner. This work reports...