BOMBESIN

作品数：16被引量：56H指数：4
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相关领域：医药卫生更多>>
相关作者：龚明福杨华史继云陈名道更多>>
相关机构：空军军医大学（第四军医大学）第三军医大学新桥医院中国原子能科学研究院重庆市中医院更多>>
相关期刊：《Chinese Medical Journal》《生理学报》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金更多>>
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Molecular recognition of itch-associated neuropeptides by bombesin receptors
《Cell Research》2023年第2期184-187,共4页Changyao Li Youwei Xu Heng Liu Hongmin Cai Yi Jiang H.Eric Xu Wanchao Yin 
Ministry of Science and Technology(China)grants(2018YFA0507002 to H.E.X.);Shanghai Municipal Science and Technology Major Project(2019SHZDZX02 to H.E.X.);Shanghai Municipal Science and Technology Major Project(H.E.X.);CAS Strategic Priority Research Program(XDB37030103 to H.E.X.);National Natural Science Foundation of China(32130022 to H.E.X.,32171189 to W.Y.,and 31770796 to Y.J.);Youth Innovation Promotion Association of CAS(2021278 to W.Y.);National Science Fund for Excellent Young Scholars(82122067 to W.Y.);Key tasks of the Lingang Laboratory(LG202103-03-05 to W.Y.,and LG202101-01-03 to Y.X.);China Postdoctoral Science Foundation(2021M703341 to H.C.);National Science and Technology Major Project(2018ZX09711002 to Y.J.).In addition,this work was partially supported by High-level new R&D institute(2019B090904008);High-level Innovative Research Institute(2021B0909050003)from Department of Science and Technology of Guangdong Province;W.Y.also gratefully acknowledges the support of Sanofi Scholarship Program.
Dear Editor,Itch,especially persistent itch(or chronic pruritus)in patients with allergic skin diseases and/or neuropathic problems,significantly affects sleep,mood and individual health.Extensive efforts have been ma...
关键词：DISEASES ALLERGIC patients 
Synthesis and Radiation Dosimetry of [<sup>68</sup>Ga]-Ga-Lys<sup>1</sup>, Lys<sup>3</sup>-DOTA-Bombesin (1,14) Antagonist for PET-Imaging, as a Potential Theragnostic Tracer in Oncology
《Journal of Encapsulation and Adsorption Sciences》2020年第2期29-41,共13页Juan C. Manrique-Arias Quetzali Pitalua-Cortes Roberto Pedrero-Piedras Géiser Rodríguez-Mena Tessy López Cristian Cabezas-Ortiz Osvaldo García-Pérez 
This Bombesin (BBN), a tetradecapeptide analog of human gastrin-releasing peptide (GRP) with a high binding affinity for GRP receptors (GRPR), is over- expressed in early stages of androgen-dependent prostate carcinom...
关键词：Radiation Dosimetry Biodistribution PET Imaging Radiopharmaceutical Lys1 Lys3-DOTA-BBN (1 14) Bombesin Analogs 
Theanine improves the function of dendritic cells via the downregulation of cyclooxygenase-2 expression被引量：1
《Chinese Medical Journal》2014年第8期1545-1549,共5页Lei Mingsheng Zuo Jianhong Li Min Gu Qihua Hu Chengping 
This work was supported by grants from the National Nature Science Foundation of China （No. 81272960）, Key Research Program from Science and Technology Department of Hunan Province, China （No. 2013WK2010）, Research Program from Education Department of Hunan Province, China （No. 12C0343）, Research Program from Health Department of Hunan Province, China （No. B2012-047） and the Funds for the Development of Chemical Industry of Forest Products in Htman Province Key Laboratory （No. JDLC201203）.
Background Tumor cells can reduce the number of dendritic cells （DCs） in the tumor environment and cause DC dysfunction through autocrine or paracdne pathways. We sought to measure cyclooxygenase-2 （COX-2） express...
关键词：THEANINE dendritic cells BOMBESIN CYCLOOXYGENASE-2 
Stimulation of oval cell and hepatocyte proliferation by exogenous bombesin and neurotensin in partially hepatectomized rats被引量：2
《World Journal of Gastrointestinal Pathophysiology》2011年第6期146-154,共9页Stelios F Assimakopoulos Athanassios C Tsamandas Ilias H Alexandris Christos Georgiou Constantine E Vagianos Chrisoula D Scopa 
AIM:To investigate the effect of the neuropeptides bombesin(BBS)and neurotensin(NT)on oval cell proliferation in partially hepatectomized rats not pretreated with a known hepatocyte inhibitor.METHODS:Seventy male Wist...
关键词：Liver regeneration Partial HEPATECTOMY Hepatic PROGENITOR CELLS OVAL CELLS Apoptosis Proliferation Oxidative stress 
Enhancement of cytotoxicity of antimicrobial peptide magainin II in tumor cells by bombesin-targeted delivery被引量：4
《Acta Pharmacologica Sinica》2011年第1期79-88,共10页Shan LIU Hao YANG Lin WAN Hua-wei CAI Sheng-fu LI You-ping LI Jing-qiu CHENG Xiao-feng LU 
Acknowledgements This work was supported by the National Basic Research Program of China （2009CB522401）, and the National Natural Science Foundation of China （81072566）.
Aim： To investigate whether the conjugation of magainin II （MG2）, an antimicrobial peptides （AMPs）, to the tumor-homing peptide bombesin could enhance its cytotoxicity in tumor cells. Methods： A magainin II-bomb...
关键词：targeted cancer therapy antimicrobial peptide tumor-homing peptide BOMBESIN MAGAININ 
Pleiotropic effects of bombesin and neurotensin on intestinal mucosa: Not just trefoil peptides被引量：4
《World Journal of Gastroenterology》2008年第22期3602-3603,共2页Stelios F Assimakopoulos Chrisoula D Scopa Vassiliki N Nikolopoulou Constantine E Vagianos 
Bombesin and neurotensin are neuropeptides which exert a wide spectrum of biological actions on gastrointestinal tissues influencing intestinal growth and adaptation, intestinal motility, blood flow, secretion, nutrie...
关键词：BOMBESIN NEUROTENSIN PLEIOTROPIC NEUROPEPTIDES Regulatory peptides 
Ameliorative effects of bombesin and neurotensin on trinitrobenzene sulphonic acid-induced colitis,oxidative damage and apoptosis in rats被引量：14
《World Journal of Gastroenterology》2008年第8期1222-1230,共9页Alper Akcan Sebahattin Muhtaroglu Hulya Akgun Hizir Akyildiz Can Kucuk Erdogan Sozuer Alper Yurci Namik Yilmaz 
Grant (SBAG-105S338) from the Scientific and Technical Research Council of Turkey (TUBITAK)
AIM:To investigate the effects of bombesin (BBS) and neurotensin (NTS) on apoptosis and colitis in an ulcerative colitis model. METHODS:In this study, a total of 50 rats were divided equally into 5 groups. In the cont...
关键词：BOMBESIN NEUROTENSIN COLITIS APOPTOSIS 
Experimental obstructive jaundice alters claudin-4 expression in intestinal mucosa: Effect of bombesin and neurotensin被引量：22
《World Journal of Gastroenterology》2006年第21期3410-3415,共6页Stelios F Assimakopoulos Constantine E Vagianos Aristides S Charonis Ilias H Alexandris Iris Spiliopoulou Konstantinos C Thomopoulos Vassiliki N Nikolopoulou Chrisoula D Scopa 
AIM： To investigate the influence of experimental obstructive jaundice and exogenous bombesin （BBS） and neurotensin （NT） administration on the expression of the tight junction （TJ）-protein claudin-4 in intestin...
关键词：Obstructive jaundice Tight junctions CLAUDIN-4 Intestinal permeability Intestinal barrier Regulatory peptides BOMBESIN NEUROTENSIN 
Signal transduction of bombesin-induced circular smooth muscle cell contraction in cat esophagus
《World Journal of Gastroenterology》2006年第14期2259-2263,共5页Sung-Uk Park Chang-Yell Shin Jung-Su Ryu Hyen-O La Sun-Young Park Hyun-Ju Song Young-Sil Min Dong-Seok Kim Uy-Dong Sohn 
AIM： To investigate the mechanism of bombesin-induced circular smooth muscle cell contraction in cat esophagus. METHODS： Specific G protein or phospholipase C involved in cat esophagus contraction was identified, mu...
关键词：BOMBESIN G protein Phospholipase C Protein kinase C Protein tyrosine kinase MAP Kinase Cell contraction 
Effect of bombesin and neurotensin on gut barrier function in partially hepatectomized rats被引量：8
《World Journal of Gastroenterology》2005年第43期6757-6764,共8页Stelios F Assimakopoulos Ilias H Alexandris Chrisoula D Scopa Panagiotis G Mylonas Konstantinos C Thomopoulos Christos D Georgiou Vassiliki N Nikolopoulou Constantine E Vagianos 
AIM： To investigate the effect of regulatory peptides bombesin （BBS） and neurotensin （NT） on intestinal barrier function in partially hepatectomized rats. METHODS： Ninety male Wistar rats were randomly divided i...
关键词：HEPATECTOMY RATS BOMBESIN NEUROTENSIN Intestinal barrier Apoptosis Oxidative stress 
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