Obesity and type 2 diabetes are among the most important risk factors for severe coronavirus disease-19. Some studies have suggested that the use of insulin as a therapeutic agent to treat hyperglycemia and the metabo...
A main requirement for cells to function normally is the availability of glucose.Glucose,available either direct from circulation or storage,is converted to the essential energy that cells need to drive critical intri...
Dear editor,Sodium glucose co-transporter 2 inhibitors(SGLT2I)reduce the majority of reabsorption of glucose in the proximal tubules,which reduces blood glucose levels by allowing excretion of excess glucose in the ur...
the Natural Science Foundation of Henan Province(Nos.202300410462,20A320012).
To the Editor:Toxoplasma gondii is a widespread apicomplexan parasite and can infect virtually all warm-blooded vertebrates.[1]Between 22%and 84%of the population in both developed and developing countries is chronica...
This study was supported by National Major Science and Technology Projects of China(No.2017ZX10203207);National Natural Science Foundation of China(No.81472677).
Metastasis and metabolism reprogramming are two major hallmarks of cancer.In the initiation and progression of cancer,tumor cells are known to undergo fundamental metabolic changes to sustain their development and pro...
This work was supported by the grants from the Young Scientist Foundation of NSFC(No.31822017);Zhejiang Provincial Natural Science Foundation of China(No.LR 19C080001);the National Natural Science Foundation of China(Nos.81572651 and 81771675);the Fundamental Research Funds for the Central Universities.
Interleukin-33(IL-33)is produced by various types of cells under physical or pathological condi-tions.As a multifunctional partner in|health and disease,current evidence reveals that IL33 also participates in several ...
This study was supported by Technology Innovation Team Train Project of Fuzhou Health Committee in China(2016-S-wp1);sponsored by key Clinical Specialty Discipline Construction Program Fuzhou,Fujian,China(201610191).
Background The interaction of adropin,glucagon-like peptide-2(GLP2),angiopoietin-like protein 4(ANGPTL4),and with childhood obesity and glucose metabolism is inconsistent.This study is to evaluate the association of t...
Objective To observe the effects of excessive fluorideon osteocalcin and glucose metabolism in mice.Methods Thirty-two male C57 mice ( body mass: 18-24 g) were selected as study subjects which were randomizedinto four...
supported by the National Natural Science Foundation of China(81771391,81401073);Chongqing Municipal Public Health Bureau,Chongqing People’s Municipal Government(20142026);the Program for Innovative Research Team of Chongqing Kuanren Hospital,China
Zinc-α2-glycoprotein(ZAG), encoded by the AZGP1 gene, is a major histocompatibility complex I molecule and a lipid-mobilizing factor. ZAG has been demonstrated to promote lipid metabolism and glucose utilization, and...
The goal of our preliminary study is to show that a minimal of overall body toxicity while maximizing the cancer tumor treatment may be achieved in a novel approach where minute amounts of coated nanoparticles may be ...