PHOSPHOINOSITIDES

作品数:10被引量:109H指数:2
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相关领域:生物学更多>>
相关作者:蔡文杰更多>>
相关机构:复旦大学上海医学院上海理工大学更多>>
相关期刊:《Virologica Sinica》《Stress Biology》《World Journal of Hepatology》《Neural Regeneration Research》更多>>
相关基金:国家自然科学基金更多>>
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Role of lipids in the control of autophagy and primary cilium signaling in neurons被引量:1
《Neural Regeneration Research》2024年第2期264-271,共8页María Paz Hernández-Cáceres Daniela Pinto-Nuñez Patricia Rivera Paulina Burgos Francisco Díaz-Castro Alfredo Criollo Maria Jose Yañez Eugenia Morselli 
funded by grants from Fondo Nacional de Desarrollo Científico y Tecnológico,FONDECYT 1200499 to EM,11200592 to MJY,1211329 to AC;by the ANID PIA ACT172066 to EM and AC;by the ANID postdoctoral fellowship 3210630 to MPHC;by the ANID doctoral fellowship 21230122 to DPN;by the ANID doctoral fellowship 21211189 to PR;by the ANID doctoral fellowship by the ANID doctoral fellowship 21210611 to FDC。
The brain is,after the adipose tissue,the organ with the greatest amount of lipids and diversity in their composition in the human body.In neurons,lipids are involved in signaling pathways controlling autophagy,a lyso...
关键词:autophagic flux CHOLESTEROL fatty acids GPCR lysosomal storage diseases NEURONS NPC1 PHOSPHOINOSITIDES primary cilium 
Phosphoinositides in plant-pathogen interaction:trends and perspectives
《Stress Biology》2023年第1期52-68,共17页Fauzia Zarreen Kamal Kumar Supriya Chakraborty 
Financial support from DST FIST Ⅱ and DBT BUILDER to SC(SC/DBT-BUILDER/2022)is gratefully acknowledged;SERB and CSIR for providing National Post-doctoral fellowship and Ph.D.scholarship,respectively.
Phosphoinositides are important regulatory membrane lipids,with a role in plant development and cellular function.Emerging evidence indicates that phosphoinositides play crucial roles in plant defence and are also uti...
关键词:Plant virus KINASES PHOSPHOINOSITIDES PHOSPHATIDYLINOSITOL PLANT-PATHOGEN SIGNALLING 
Emerging roles of phosphoinositide-associated membrane trafficking in plant stress responses被引量:1
《Journal of Genetics and Genomics》2022年第8期726-734,共9页Feng Lin Junming Zheng Yanhua Xie Wen Jing Qun Zhang Wenhua Zhang 
the National Natural Science Foundation of China (32100553, 32171956, and 31770294);Natural Science Foundation of Jiangsu Province (BK20200555);the Fundamental Research Funds for the Central Universities, and a start-up fund for advanced talents from Nanjing Agricultural University (680-804016 to F.L.)
Eukaryotic cells are confined by membranes that create hydrophobic barriers for substance and information exchange between the inside and outside of the cell.These barriers are formed by assembly of lipids and protein...
关键词:PHOSPHOINOSITIDES Membrane trafficking PLANT Stress response 
Cytoplasmic domain and enzymatic activity of ACE2 are not required for PI4KB dependent endocytosis entry of SARS-CoV-2 into host cells
《Virologica Sinica》2022年第3期380-389,共10页Hang Yang Huijun Yuan Xiaohui Zhao Meng Xun Shangrui Guo Nan Wang Bing Liu Hongliang Wang 
supported by the National Natural Science Foundation of China(81871662,82150201);Xi’an Jiaotong University Fund(xzy012019066 and xzy032020037);Xi’an Jiaotong University Health Science Center-Qinnong Bank Fund(QNXJTU-04&QNXJTU-07)。
The recent COVID-19 pandemic poses a global health emergency.Cellular entry of the causative agent SARS-CoV-2 is mediated by its spike protein interacting with cellular receptor-human angiotensin converting enzyme 2(A...
关键词:SARS-CoV-2 ENDOCYTOSIS PHOSPHOINOSITIDES Angiotensin converting enzyme 2(ACE2) SYNCYTIUM 
Phosphoinositides:Emerging players in plant salinity stress tolerance
《Molecular Plant》2021年第12期1973-1975,共3页Sergey Shabala Min Yu 
supported by the National Natural Science Foundation of China(project 31870249);the National Distinguished Expert Project(WQ20174400441);the Australian Research Council(DP 170100430);grant 31961143001 for Joint Research Projects between Pakistan Science Foundation and National Natural Science Foundation China to S.S.
Soil salinity reduces the biodiversity of natural ecosystems and severely limits sustainability and profitability of agricultural pro-duction systems.Given the increasing reliance of modern agricul-ture on irrigation(...
关键词:soil SALINITY GERMPLASM 
Distinct phosphoinositides define the biotrophic interface of plant-microbe interactions
《Molecular Plant》2021年第8期1223-1225,共3页Li Qin Yangdou Wei 
supported by grants from the Natural Sciences and Engi-neering Research Council of Canada(Discovery Grant);the Canadian Foundation for Innovation.
Phosphoinositides,also known as phosphatidylinositol phosphates(PIPs),are a minor class of anionic phospholipids in cell membranes that have profound importance in a variety of cellular processes,such as cell signalin...
关键词:DYNAMICS INTERFACE POSITIONS 
PI3K/SHIP2/PTEN pathway in cell polarity and hepatitis C virus pathogenesis被引量:2
《World Journal of Hepatology》2017年第1期18-29,共12页Aline Awad Ama Gassama-Diagne 
Supported by Agence Nationale de Recherche sur le Sida et les hépatites(ANRS,France),Ligue contre le cancer,France
Hepatitis C virus(HCV) infects hepatocytes, polarized cells in the liver. Chronic HCV infection often leads to steatosis, fibrosis, cirrhosis and hepatocellular carcinoma, and it has been identified as the leading cau...
关键词:Hepatitis C virus Phosphoinositide 3-kinase SH2-containing inositol polyphosphate 5-phosphatase Epithelial cell polarity PHOSPHOINOSITIDES 
Homotypic Vacuole Fusion Requires VTI11 and Is Regulated by Phosphoinositides被引量:2
《Molecular Plant》2014年第6期1026-1040,共15页Sang Won Han Maria Fernanda Rodriguez-Welsh Marcela Rojas-Pierce 
Most plant cells contain a large central vacuole that is essential to maintain cellular turgor. We report a new mutant allele of VTI11 that implicates the SNARE protein VTI11 in homotypic fusion of protein storage and...
关键词:VACUOLE SNARE PHOSPHOINOSITIDES membrane fusion Wortmannin. 
Physiological functions of Atg6/Beclin 1: a unique autophagy-related protein被引量:103
《Cell Research》2007年第10期839-849,共11页Yang Cao Daniel J Klionsky 
The most striking morphological feature of eukaryotic cells is the presence of various membrane-enclosed compartments. These compartments, including organelles and transient transport intermediates, are not static. Ra...
关键词:LYSOSOME PHOSPHOINOSITIDES protein targeting stress VACUOLE YEAST 
Phosphoinositides as ligands of PHD-fingers: implications for chromatin remodeling
《Cell Research》2002年第3期297-297,共1页ORGOZANI PHILIPKARUMAN SETHFIELD JAMESCHA JENNIFERVILLASENOR VIKRAMRRAO JOANSBRUGGE LEWISCCANTLEY CHERYLLBAIRD BHARATMEHROTRA DAVIDGMYSZKA COLINGFERGUSON GLENNDPRESTWICH 
Phosphatidylinositol phosphates (PtdInsPs) play critical roles in signal transduction pathways, cytoskele-tal regulation, and vesicular trafficking and are implicated in multiple disease pathways. In the nucleus, Ptdl...
关键词:磷酸肌醇 PHD指蛋白 配基 染色质重构型 
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