FIBROCYTE

作品数：9被引量：61H指数：5
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相关领域：医药卫生更多>>
相关机构：第四军医大学口腔医院更多>>
相关期刊：《World Journal of Stem Cells》《Chinese Medical Journal》《Advances in Bioscience and Biotechnology》《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》更多>>
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Fibrocyte enrichment and myofibroblastic adaptation causes nucleus pulposus fibrosis and associates with disc degeneration severity
《Bone Research》2025年第1期170-182,共13页Yi Sun Yan Peng Zezhuo Su Kyle K.H.So Qiuji Lu Maojiang Lyu Jianwei Zuo Yongcan Huang Zhiping Guan Kenneth M.C.Cheung Zhaomin Zheng Xintao Zhang Victor Y.L.Leung 
jointly General Research Fund(17121619)of the Research Grant Council of Hong Kong;Guangdong Basic and Applied Basic Research Foundation(2024A1515010104 and 2023A1515220095);Scientific Research Foundation of Peking University Shenzhen Hospital(KYQD202100X)。
Fibrotic remodeling of nucleus pulposus(NP)leads to structural and mechanical anomalies of intervertebral discs that prone to degeneration,leading to low back pain incidence and disability.Emergence of fibroblastic ce...
关键词：DEGENERATION SEVERITY markedly 
Constitutive AKT Activity Predisposes Lung Fibrosis by Regulating Macrophage, Myofibroblast and Fibrocyte Recruitment and Changes in Autophagy被引量：2
《Advances in Bioscience and Biotechnology》2019年第10期346-373,共28页Duaa Dakhlallah Yijie Wang Tierra A. Bobo Emily Ellis Xiaokui Mo Melissa G. Piper Timothy D. Eubank Clay B. Marsh 
The etiology and pathogenesis of pulmonary fibrosis is poorly understood. We and others reported that M-CSF/CSF-1, M-CSF-R and downstream AKT activation plays an important role in lung fibrosis in mice models and in I...
关键词：Pulmonary Fibrosis AKT CSF1 M-CSF Receptor MACROPHAGE MYOFIBROBLAST FIBROCYTES AUTOPHAGY 
Potential Role of Interleukin-25/Interleukin-33/Thymic Stromal Lymphopoietin-Fibrocyte Axis in the Pathogenesis of Allergic Airway Diseases被引量：14
《Chinese Medical Journal》2018年第16期1983-1989,共7页Xiu-Juan Yao Xiao-Fang Liu Xiang-Dong Wang 
This study was supported by grants from the Natural Science Foundation of China （No. 81641003） and Application of Clinical Features in Capital City by the Beijing Municipal Science and Technology Commission （No. Z131107002213135）.
Objective： Allergic airway diseases （AADs） are a group of heterogeneous disease mediated by T-helper type 2 （Th2） immune response and characterized with airway inflammation and remodeling, including allergic asth...
关键词：Allergic Airway Diseases Axis CROSSTALK FIBROCYTE Interleukin-25/Interleukin-33/Thymic Stromal Lymphopoietin 
The Role of Fibrocyte in the Pathogenesis of Silicosis被引量：22
《Biomedical and Environmental Sciences》2018年第4期311-316,共6页LI Juan YAO Wu HOU Jian Yong ZHANG Lin BAO Lei CHEN Hui Ting WANG Di YUE Zhong Zheng LI Yi Ping ZHANG Miao YU Xing Hao ZHANG Jian Hui QU Ya Qian HAO Chang Fu 
supported by grants from the National Natural Science Foundation of China[No.81472954]
Exposure to free silica induces silicosis and myofibroblasts are regarded as primary effector cells.Fibrocytes can differentiate into myofibroblast.
关键词：SMA Figure 
Crystalline Silica Promotes Rat Fibrocyte Differentiation in Vitro,and Fibrocytes Participate in Silicosis in Vivo被引量：7
《Biomedical and Environmental Sciences》2017年第9期649-660,共12页LI Juan YAO Wu HOU Jian Yong Zhang Lin BAO Lei CHEN Hui Ting WANG Di YUE Zhong Zheng LI Yi Ping ZHANG Miao HAO Chang Fu 
supported by grants from the National Natural Science Foundation of China(No.81472954)
Objective The aim of this study was to investigate the effects of Si O2 on fibrocytes and whether fibrocytes participate in silicosis in vivo. Methods A macrophagocyte（AM）/fibrocyte coculture system was established,...
关键词：FIBROCYTE Crystalline silica Macrophagocyte DIFFERENTIATION 
Pathogenetic and prognostic roles of bloodborne fibrocytes in asthma被引量：2
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2015年第8期651-660,共10页Sabrina MATTOLI 
Bloodborne fibrocytes are cells mobilized from the bone marrow, which express surface antigens commonly ascribed to hematopoietic progenitors and have phenotypic and functional characteristics similar to those of imma...
关键词：Airway remodeling ASTHMA BIOMARKER Chronic inflammation FIBROCYTE 
Hematopoietic stem cell-derived adipocytes and fibroblasts in the tumor microenvironment被引量：6
《World Journal of Stem Cells》2015年第2期253-265,共13页Ying Xiong Lindsay T Mc Donald Dayvia L Russell Ryan R Kelly Katie R Wilson Meenal Mehrotra Adam C Soloff Amanda C LaRue 
Supported by In part by the NIH/NCI(R01 CA148772,ACL);the Biomedical Laboratory Research and Development Program of the Department of Veterans Affairs(Merit Awards,ACL);the Hollings Cancer Center(Translational Research Pilot Project,P30 CA138313,ACL)
The tumor microenvironment(TME) is complex and constantly evolving. This is due, in part, to the crosstalk between tumor cells and the multiple cell types that comprise the TME, which results in a heterogeneous popula...
关键词：Hematopoietic stem CELL CANCER associatedadipocyte Mesenchymal STROMAL CELL Tumor progression CANCER associated fibroblast Plasticity Metastasis FIBROCYTE 
Establishment and identification of induced pluripotent stem cells in liver cancer patients被引量：1
《Asian Pacific Journal of Tropical Medicine》2014年第4期253-256,共4页Da-Ming Zhang Jian-Jun Li Peng Yan Jian-Ting Hu 
supported by Science and Technology Project of Henan Provincial Department of Health(NO:2011020038)
Objective:To induce pluripotent stem(IPS)cells from fibrocytes that are separated from liver cancer patients.Methods:The fibrocytes were reprogrammed to IPS cells by lentiviral vector,stained and identified by immunoh...
关键词：FIBROCYTE LIVER cancer Induced PLURIPOTENT STEM cells ESTABLISHMENT 
Aging promotes pro-fibrotic matrix production and increases fibrocyte recruitment during acute lung injury被引量：8
《Advances in Bioscience and Biotechnology》2014年第1期19-30,共12页Viranuj Sueblinvong Wendy A. Neveu David C. Neujahr Stephen T. Mills Mauricio Rojas Jesse Roman David M. Guidot 
Fibrotic lung diseases increase with age. Previously we determined that senescence increases tissue expression of fibronectin EDA (Fn-EDA) and decreases fibroblast expression of Thy-1, and that fibrocytes contribute t...
关键词：Lung Fibrosis THY-1 FIBROCYTES Extracellular Matrix FIBRONECTIN TGFβ1 
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