funded by the Establishment of Real World Data-based Clinical Evidence of Korean Medicine Health Technology(No.KSN1823211);Additionally,it received support from a National Research Foundation of Korea grant funded by the Korean government(No.NRF-2022R1C1C2008738).
Background Acupotomy,a more invasive procedure than acupuncture,involves the use of a thicker needle with an integrated knife at the tip,necessitating safety research.We aimed to define relevant adverse events(AEs)and...
Supported by the National Natural Science Foundation of China(No.81774436);the Science and Technology Innovation Fund Project of Anhui University of Traditional Chinese Medicine(No.2021ZC02);the“14th Five-Year Plan”Provincial Traditional Chinese Medicine Advantage Characteristic Specialty Project[No.(2021]71)]。
Objective:To explore the effect of acupotomy intervention on autophagy of chondrocytes in rabbits with knee osteoarthritis(KOA),and to determine the possible mechanisms of acupotomy to alleviate cartilage degeneration...
supported by the National Natural Science Foundation of China(82074523);the National Natural Youth Science Foundation of China(82004448).
Objective:To investigate the effects of acupotomy on skeletal muscle fibrosis and collagen deposition in a rabbit knee osteoarthritis(KOA)model.Methods: Rabbits(n=18)were randomly divided into control,KOA,and KOA+acup...
Supported by the Beijing University of Chinese Medicine Research Platform Construction Project(No.2023-JYB-KYPT-11)。
Objective To determine whether acupotomy ameliorates immobilization-induced muscle contracture and fibrosis via Wnt/β-catenin signaling pathway.Methods Thirty Wistar rats were randomly divided into 5 groups(n=6)by a ...
Key Project of Beijing University of Chinese Medicine:to Investigate the Effect of Acupotomy Mechanics on Oxidative Injury of Rabbit Chondrocytes with Knee Osteoarthritis Based on Mitophagy Mediated by Pink1/Parkin Signaling Pathway(2020-JYB-ZDGG-059);National Natural Science Foundation of China:to Investigate the Mechanism of Acupotomy"Regulating Tendon and Treating Bone"in the Treatment of Knee Osteoarthritis based on the Vascularization of Hypoxic Cartilage Mediated by Hypoxia-Inducible Factor 1alpha/Vascular Endothelial Growth Factor Pathway(82074523)。
OBJECTIVE:To investigate the effect of acupotomy,on mitophagy and the Pink1-Parkin pathway in chondrocytes from rabbits with knee osteoarthritis(KOA).METHODS:A KOA model was established via the modified Videman method...
Objective To observe the clinical efficacy of acupotomy combined with metformin hydrochloride tablet for type 2 diabetes mellitus(T2DM)and its effect on serum levels of inflammatory factors.Methods A total of 68patien...
supported by the Beijing Municipal Natural Science Foundation(7192110)。
Objective:To investigate whether acupotomy could inhibit subchondral bone remodeling in knee osteoarthritis(KOA)rabbits by regulating the activity of osteoblasts and osteoclasts.Methods:KOA rabbits were prepared by im...
Longitudinal Research Development Fund of Beijing University of Chinese Medicine:to Investigate the Effect of Acupotomy on Subchondral Bone Remodeling in Knee Osteoarthritis Based on BMP2-Smad1 Pathway(2020-ZXFZJJ-031);National Natural Science Foundation of China:to Investigate the Mechanism of Acupotomy"Regulating Tendon and Treating Bone"in the Treatment of KOA based on the Vascularization of Hypoxic Cartilage Mediated by HIF-1α/VEGF Pathway(82074523)。
OBJECTIVE:To investigate the effects of acupotomy on the subchondral bone absorption and mechanical properties in rabbits with knee osteoarthritis(KOA).METHODS:The rabbits were divided into blank control,model,acupoto...
Supported by the National Natural Science Foundation of China:81774436。
ObjectiveTo elucidate the mechanism underlying the inhibitory effect of acupotomy on chondrocyte apoptosis in rabbits with knee osteoarthritis (KOA) through screening, analysis, and verification of apoptosis-related d...
funded by the Korea Institute of Oriental Medicine(No.K18121);supported by the National Research Foundation of Korea grant funded by the Korea Government(Ministry of Science and ICT)(No.NRF-2022R1C1C2008738)。
Objective:Acupotomy is a modern acupuncture method that includes modern surgical methods.Since acupotomy is relatively more invasive than filiform acupuncture treatment,it is important to establish the safety profile ...