云南高校图书馆联盟文献共享服务平台- PICROTOXIN

PICROTOXIN: 作品数：10被引量：15H指数：3; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：岳旺王蕾张芳周明刘艳霞更多>>; 相关机构：复旦大学青岛大学中国科学院上海生命科学研究院中国医学科学院基础医学研究所更多>>; 相关期刊：《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《Science Bulletin》《Neuroscience Bulletin》更多>>; 相关基金：国家自然科学基金更多>>

Propofol decreases the excitability of cholinergic neurons in mouse basal forebrain via GABAa receptors被引量：7: 《Acta Pharmacologica Sinica》2019年第6期755-761,共7页Lei Chen Zhi-lai Yang Juan Cheng Ping-ping Zhang Le-sha Zhang Xue-sheng Liu Lie-cheng Wang; National Natural Science Foundation of China (81571293 to LcW;81500949 to Z-IY;81571039 to X-sL);National Century Excellent Talents in University of China (gxbjZD2016034 to L-cW).; Propofol is an intravenous anesthetic that can active y-aminobutyric acid A (GABAa) receptors and generate sedative-hypnotic effects. Propofol has been widely applied clinically to achieve sedation comparable to sleep...; 关键词：PROPOFOL basal FOREBRAIN CHOLINERGIC neurons PICROTOXIN GABAA receptors anesthesia

Terminalia arjuna bark extract attenuates picrotoxin-induced behavioral changes by activation of serotonergic,dopaminergic,GABAergic and antioxidant systems: 《Chinese Journal of Natural Medicines》2017年第8期584-596,共13页Chandra Sekhar Y Phani Kumar G Anilakumar K.R.; Stress and emotion are associated with several illnesses from headaches to heart diseases and immune deficiencies to central nervous system. Terminalia arjuna has been referred as traditional Indian medicine for sever...; 关键词：Anxiety Terminalia arjuna Gene expression PICROTOXIN NEUROTRANSMITTERS LC-MS

Evaluation of the anticonvulsant activity of the essential oil of Myrothamnus moschatus in convulsion induced by pentylenetetrazole and picrotoxin: 《Asian Pacific Journal of Tropical Biomedicine》2016年第6期501-505,共5页Emmanuel Randrianarivo Filippo Maggi Marcello Nicoletti Philippe Rasoanaivo; Supported by the University Research Fund 2014/2015 of the University of Camerino under the grant number FPI000044; Objective: To evaluate the anticonvulsant effect of the essential oil of Myrothamnus moschatus(M. moschatus) in convulsion induced by pentylenetetrazole and picrotoxin in rodent models.Methods: The essential oil of th...; 关键词：Myrothamnus moschatus ESSENTIAL OIL CONVULSIONS PENTYLENETETRAZOLE PICROTOXIN

The GABA Antagonist Picrotoxin Attenuates an Ethanol-Induced Taste Aversion in Taste Aversion-Prone Rats: 《Neuroscience & Medicine》2011年第4期363-369,共7页Joseph Tkacz Stephen Hobbs Ralph Elkins; The aversive properties of alcohol can be examined by using ethanol as a conditioning agent in a taste aversion (TA) paradigm. However, there is often variability in how organisms respond to the aversive properties of...; 关键词：Conditioned Taste AVERSION ETHANOL GABA PICROTOXIN RATS

Changes of paired-pulse evoked responses during the development of epileptic activity in the hippocampus被引量：1: 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2011年第9期704-711,共8页Zhou-yan FENG Xiao-jing ZHENG Cong TIAN Yang WANG Hao-yu XING; Project (Nos. 30770548 and 30970753) supported by the National Natural Science Foundation of China; Dysfunction of inhibitory synaptic transmission can destroy the balance between excitatory and inhibitory synaptic inputs in neurons,thereby inducing epileptic activity.The aim of the paper is to investigate the effec...; 关键词：EPILEPSY Paired-pulse depression γ-Aminobutyric acid（GABA） Picrotoxin（PTX） CA1 region In-vivo

Urotensin Ⅱ inhibits electrical activity of hippocampal CA1 neurons by potentiating the GABA_A receptor-mediated Cl^- current被引量：3: 《Neuroscience Bulletin》2006年第2期110-114,共5页Yu-Ming WU Ru WANG Rui-Rong HE; Objective To examine the effects of urotensin Ⅱ （UⅡ） on the discharges of neurons in CA1 area of hippocampal slices by using extracellular recording technique. Results ①In response to the application of UⅡ （0.3...; 关键词：hippocampal slice urotensin Ⅱ BICUCULLINE L-NAME PICROTOXIN

Increase in drug-induced seizure susceptibility of transgenic mice overexpressing GABA transporter-1被引量：1: 《Acta Pharmacologica Sinica》2003年第10期991-995,1061,共6页赵文娟马映华费俭梅镇彤郭礼和; AIM: The changes of seizure susceptibility of transgenic mice overexpressing GABA transporter-1(GAT-1) were studied to clarify the possible role of GABAergic transmission in epileptogenesis. METHODS: Seizures were ind...; 关键词：neutrotransmitter transporter carrier proteins seizures GABA PENTYLENETETRAZOL PICROTOXIN kainic acid ethyl nipecotate transgenic mice

Inhibitory effects of succinic acid on chemical kindling and amygdala electrical kindling in rats被引量：3: 《Acta Pharmacologica Sinica》2002年第9期847-850,共4页岳旺刘艳霞臧东莲周明张芳王蕾; Project supported by the Educational Committee of China,№[1995]806.; AIM: To investigate the effects and mechanism of succinic acid on pentylenetetrazol (PTZ) chemical kindling and amygdala electrical kindling in rats. METHODS: PTZ chemical kindling and amygdala electrical kindling mod...; 关键词：KINDLING EPILEPSY succinic acid PICROTOXIN GABA-A receptors

Picrotoxin对家兔急性低氧循环反应的效应: 《青海医学院学报》1996年第1期11-13,共3页许存和何加强孟宪法王建新; 青海省卫生厅资助; 本研究观察了Picrotoxin对家兔急性低氧循环反应的效应，从而探讨GABA在家兔低氧循环反应中的作用。动物麻醉制动，经人工呼吸机吸入11％低氧混合气。动物分两组，对照组（n＝11）静脉注射盐水（1ml／kg），实验组（n＝8）静脉注射Picro...; 关键词：急性低氧家兔血压心率 Γ-氨基丁酸

Temporal coding of auditory tonic neurons in bushcricketand effects of GABA: 《Chinese Science Bulletin》1995年第9期768-772,共5页沈钧贤于琦; Project supported by the National Natural Science Foundation of China.; Acoustic communication plays an important role in the behavior of insects, such asmating, aggression or alarm, and preying. A typical example is that female bushcrickets(Orthoptera) can approach phonotactically toward...; 关键词：AUDITORY TONIC NEURONS GABA PICROTOXIN d-tubocurarine bushcricket.

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