FOREBRAIN

作品数：14被引量：20H指数：3
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相关领域：医药卫生更多>>
相关作者：刘璇朱兴族耿昱更多>>
相关机构：中国科学院上海生命科学研究院浙江大学医学院附属邵逸夫医院更多>>
相关期刊：《Neural Regeneration Research》《Science Bulletin》《Journal of Behavioral and Brain Science》《Chinese Journal of Natural Medicines》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Forebrain excitatory neuron-specific loss of Brpf1 attenuates excitatory synaptic transmission and impairs spatial and fear memory被引量：4
《Neural Regeneration Research》2024年第5期1133-1141,共9页Baicheng Zhao Hang Zhang Ying Liu Gaoyu Zu Yuxiao Zhang Jiayi Hu Shuai Liu Linya You 
supported by the National Natural Science Foundation of China,No. 81771228;Shanghai Association of Science and Technology,Nos. 22WZ2501700 and 23WZ2504500 (all to LY)
Bromodomain and plant homeodomain(PHD)finger containing protein 1(Brpf1)is an activator and scaffold protein of a multiunit complex that includes other components involving lysine acetyltransferase(KAT)6A/6B/7.Brpf1,K...
关键词：behavioral test Brpf1 CAMKIIa-Cre intellectual disability miniature excitatory postsynaptic current MRNA-SEQ 
Enhanced replication of SARS-CoV-2 Omicron BA.2 in human forebrain and midbrain organoids被引量：2
《Signal Transduction and Targeted Therapy》2022年第12期4257-4260,共4页Yuxin Hou Chang Li Chaemin Yoon On Wah Leung Sikun You Xiaoming Cui Jasper Fuk-Woo Chan Duanqing Pei Hoi Hung Cheung Hin Chu 
Health and Medical Research Fund(CID-HKU1–5,COVID1903010–7 and-14,and 20190652);Food and Health Bureau,the Government of the Hong Kong Special Administrative Region,General Research Fund(14104321,14109920,14121618,14169717,17118621,and 17123920);Collaborative Research Fund(C7060-21GF);Theme-Based Research Scheme(T11-709/21-N),Research Grants Council,the Government of the Hong Kong Special Administrative Region;Health@InnoHK,Innovation and Technology Commission,the Government of the Hong Kong Special Administrative Region;National Natural Science Foundation of China Excellent Young Scientists Fund(Hong Kong and Macao)(32122001);the Consultancy Service for Enhancing Laboratory Surveillance of Emerging Infectious Diseases and Research Capability on Antimicrobial Resistance for Department of Health of the Hong Kong Special Administrative Region Government;Emergency Collaborative Project(EKPG22-01)of Guangzhou Laboratory;Emergency COVID-19 Project(2021YFC0866100),Major Projects on Public Security,National Key Research and Development Program;Sanming Project of Medicine in Shenzhen,China(SZSM201911014);the High Level-Hospital Program,Health Commission of Guangdong Province,China;the University of Hong Kong Outstanding Young Researcher Award;the University of Hong Kong Research Output Prize(Li Ka Shing Faculty of Medicine).
Dear Editor,Coronavirus Disease 2019(COVID-19)is associated with a variety of neurological complications,including encephalopathy,encephalitis,dementia,and others.1 The pathogenic mechanism of these neurological manif...
关键词：INVASION finding INCOMPLETE 
Hypothermia selectively protects the anterior forebrain mesocircuit during global cerebral ischemia
《Neural Regeneration Research》2022年第7期1512-1517,共6页Xiao-Hua Wang Wei Jiang Si-Yuan Zhang Bin-Bin Nie Yi Zheng Feng Yan Jian-Feng Lei Tian-Long Wang 
supported by Beijing Municipal Health Commission of China,No.Jing2019-2(to TLW)。
Hypothermia is an important protective strategy against global cerebral ischemia following cardiac arrest.However,the mechanisms of hypothermia underlying the changes in different regions and connections of the brain ...
关键词：anterior forebrain mesocircuit cardiac arrest corpus callosum global cerebral ischemia hypometabolic areas HYPOTHERMIA magnetic resonance imaging positron emission tomography prefrontal cortex rats THALAMUS 
A Functional Inhibitory Role of Habenular Glucagon-Like Peptide-1 (GLP-1) in Forebrain Reward Signaling
《Journal of Behavioral and Brain Science》2021年第9期205-215,共11页Max Johnson Alev M. Brigande Jiahe Yue Kayla J. Colvin Olivia Dao Paul J. Currie 
There is emerging evidence implicating glucagon-like peptide-1 (GLP-1) in reward, including palatable food reinforcement and alcohol-based reward circuitry. While recent findings suggest that mesolimbic structures, su...
关键词：Alcohol ANHEDONIA Appetitive Motivation Brain Reward Ethanol Exendin-4 GLP-1 Receptors Operant Responding Palatable Food Intake Reward Salience 
Insights into ligand expression heterogeneity across multiple cell types in the adult forebrain that regulates neural stem cell behavior
《Neural Regeneration Research》2019年第8期1369-1371,共3页Rainer Akkermann Kasum Azim 
supported by the German Research Council(DFG;AZ/115/1-1);the Swiss National Funds(P300PA_171224,to KA)
In the adult mammalian central nervous system (CNS), neural cell generation is restricted to two highly specialized germinal niches. These are the subventricular zone (SVZ) that borders the forebrain lateral ventricle...
关键词：INSIGHTS LIGAND EXPRESSION cell BEHAVIOR 
Propofol decreases the excitability of cholinergic neurons in mouse basal forebrain via GABAa receptors被引量：7
《Acta Pharmacologica Sinica》2019年第6期755-761,共7页Lei Chen Zhi-lai Yang Juan Cheng Ping-ping Zhang Le-sha Zhang Xue-sheng Liu Lie-cheng Wang 
National Natural Science Foundation of China (81571293 to LcW;81500949 to Z-IY;81571039 to X-sL);National Century Excellent Talents in University of China (gxbjZD2016034 to L-cW).
Propofol is an intravenous anesthetic that can active y-aminobutyric acid A (GABAa) receptors and generate sedative-hypnotic effects. Propofol has been widely applied clinically to achieve sedation comparable to sleep...
关键词：PROPOFOL basal FOREBRAIN CHOLINERGIC neurons PICROTOXIN GABAA receptors anesthesia 
Neuroprotective effect of the ethanol extract of Artemisia capillaris on transient forebrain ischemia in mice via nicotinic cholinergic receptor被引量：2
《Chinese Journal of Natural Medicines》2018年第6期428-435,共8页Huiyoung Kwon Ji Wook Jung Young Choon Lee Jong Hoon Ryu Dong Hyun Kim 
supported by Dong-A University Research Supporting Program
Artemisia capillaris Thunberg is a medicinal plant used as a traditional medicine in many cultures. It is an effective remedy for liver problems including hepatitis. Recent pharmacological reports have indicated that ...
关键词：ARTEMISIA capillaris Transient FOREBRAIN ISCHEMIA ACETYLCHOLINESTERASE NICOTINIC ACETYLCHOLINE receptor 
Toward a neurobiology of auditory object perception： What can we learn from the songbird forebrain？
《Current Zoology》2011年第6期671-683,共13页Kai LU, David S. VICARIO 
In the acoustic world, no sounds occur entirely in isolation; they always reach the ears in combination with other sounds. How any given sound is discriminated and perceived as an independent auditory object is a chal...
关键词：SONGBIRD Object perception Auditory scene analysis Neural selectivity Plasticity Stimulus-specific adaptation 
Correlation between synaptic protein expression and synaptic reorganization in the hippocampal CA3 region in a rat model of post-traumatic epilepsy
《Neural Regeneration Research》2010年第15期1156-1160,共5页Gaolian Zhang Jianmin Huang Bang Zhao Haineng Huang Yuanyang Deng HuadongHuang Qirong He Jianping Liang 
the General Program of Department of Education of Guangxi Zhuang Autonomous Region,No.Guijiaokeyan[2007]34
Postsynaptic density protein-95 and synaptophysin participate in synaptic reorganization in the forebrain of epilepsy models. However, the time-effect relationship between dynamic synapsin expression in hippocampus an...
关键词：post-traumatic epilepsy HIPPOCAMPUS FeCI2 FOREBRAIN postsynaptic density protein-95 SYNAPTOPHYSIN brain injury neural regeneration 
GluR-B亚单位改变在GluR-B^(ΔECS.Forebrain)小鼠癫痫形成中的作用
《现代实用医学》2005年第10期602-603,614,共3页耿昱 
目的探讨G luR-B亚单位表达变化在癫痫形成中的机制。方法采用W estern b lot方法研究G luR-BΔECS.Forebrain小鼠海马G luR-B亚单位的表达变化。结果(1)TgC re4和G luR-Bneo小鼠杂交子代中约25%是G luR-BΔECS.Forebrain小鼠,该鼠系从...
关键词：癫痫/病因学 小鼠 转基因 GluR-B亚单位 海马 
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