POSTCONDITIONING

作品数:38被引量:305H指数:10
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相关领域:医药卫生更多>>
相关作者:薛枫蒋文平李勋韩莲花蒋廷波更多>>
相关机构:苏州大学哈尔滨医科大学天津市第三中心医院首都医科大学更多>>
相关期刊:《中国急救医学》《Chinese Journal of Traumatology》《Acta Pharmacologica Sinica》《中国现代医学杂志》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划湖北省自然科学基金山西省自然科学基金更多>>
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Pim-1 Kinase Regulating Dynamics Related Protein 1 Mediates Sevoflurane Postconditioning-induced Cardioprotection被引量:7
《Chinese Medical Journal》2017年第3期309-317,共9页Jin-Dong Liu Hui-Juan Chen Da-Liang Wang Hui Wang Qian Deng 
Background: It is well documented that sevoflurane postconditioning (SP) has a significant myocardial protection effect. However, the mechanisms underlying SP are still unclear. In the present study, we investigate...
关键词:CARDIOPROTECTION Ischemia-reperfusion Injury MITOCHONDRIA PIM-1 POSTCONDITIONING SEVOFLURANE 
Up-regulation of iNOS by hypoxic postconditioning inhibits H9c2 cardiomyocyte apoptosis induced by hypoxia/re-oxygenation被引量:4
《Acta Biochimica et Biophysica Sinica》2015年第7期516-521,共6页Huanxin Zhao Rong Yang Yujuan Shi Wanfang Yang Qun Zeng Guoyi Zhao Xiaoliang Wang 
This work was supported by the grants from the National Natural Science Foundation of China (Nos. 81100150 and 81170144), and the Natural Science Foundation of Shanxi Province (No. 2012011040-1 ).
Apoptosis is a crucial mode of cell death induced by ischemia and reperfusion, and ischemic postconditioning (PostC) has been reported to inhibit cell apoptosis. Inducible nitric oxide synthase (iNOS) has been con...
关键词:inducible nitric oxide synthase hypoxic postconditioning apoptosis CARDIOMYOCYTE 
Restoration of autophagic flux in myocardial tissues is required for cardioprotection of sevoflurane postconditioning in rats被引量:27
《Acta Pharmacologica Sinica》2014年第6期758-769,共12页Yu-lin ZHANG 
Acknowledgements This work was supported by the National Natural Science Foundation of China (Grant No 81070098 and 81200109).
Aim: Sevoflurane postconditioning (SpostC) has been shown to protect the heart from ischemia-reperfusion (I/R) injury. In this study, we examined whether SpostC affected autophagic flux in myocardial tissues tha...
关键词:SEVOFLURANE inhalation anesthetics POSTCONDITIONING heart ischemia-reperfusion injury CARDIOPROTECTION AUTOPHAGY CHLOROQUINE 
Ischemic preconditioning produces more powerful anti- inflammatory and cardioprotective effects than limb remote ischemic postconditioning in rats with myocardial ischemia-reperfusion injury被引量:16
《Chinese Medical Journal》2013年第20期3949-3955,共7页Zhang Jia-qiang Wang Qiang Xue Fu-shan Li Rui-ping Cheng Yi Cui Xin-long Liao Xu Meng Fan-min 
Background Both ischemic preconditioning (IPC) and limb remote ischemic postconditioning (LRIPOC) have been shown to possess significantly different cardioprotective effects against the myocardial ischemia reperfu...
关键词:myocardial ischemia-reperfusion injury  inflammatory response  ischemia preconditioning  limb remote!schemic postconditioning 
Propofol Postconditioning Protects Cardiomyocytes from Hypoxia/ Reoxygenation Injury through Activation of the Phosphoinositide- 3-kinase/Akt Pathway
《麻醉与监护论坛》2012年第6期447-451,共5页Yun Wang Zong-ze Zhang Yun Wu Yan-lin Wang 
关键词:缺氧 复氧损伤 心肌细胞培养 异丙酚 后处理 磷酸肌醇 Bcl-2蛋白 激活 保护 
Protection of ghrelin postconditioning on hypoxia/ reoxygenation in gastric epithelial cells被引量:1
《World Journal of Gastroenterology》2012年第38期5377-5388,共12页Zhang-Bo Liu Su-Juan Fei Sheng-Ping Zhu Jin-Zhou Zhu Hong-Xia Han Qiu-Ju Dong Jian-Fu Zhang 
Supported by National Natural Science Foundation of China, No.30570671;the Educational Department Science Research Foundation of Jiangsu Province, No. 99KJB310005 and 05KJB310134
AIM: To investigate the protective effect and mechanisms of ghrelin postconditioning against hypoxia/reoxygenation (H/R)-induced injury in human gastric epithelial cells. METHODS: The model of H/R injury was establish...
关键词:Protection of ghrelin postconditioning on hypoxia/ reoxygenation in gastric epithelial cells 
Protective effect of propofol preconditioning and postconditioning against ischemic spinal cord injury被引量:11
《Neural Regeneration Research》2011年第12期951-955,共5页Qijing Yu Ji Hu Jie Yang Shuzhou Yin 
the Natural Science Foundation of Hubei Province,No.2009CDB130;Fundamental Research Funds for the Central Universities (HUST),No.M2009049
Propofol preconditioning has been shown to provide neuroprotection against spinal ischemia/reperfusion injury. In this study, spinal cord ischemia/repeffusion injury was induced by blocking the abdominal aorta in rabb...
关键词:ischemia/reperfusion injury spinal cord PROPOFOL ANTIOXIDATION neural regeneration 
Effects of isoflurane and sevoflurane postconditioning and changes in JNK1/2 pathway activity on rat brain slices subjected to oxygen and glucose deprivation in vitro
《Neural Regeneration Research》2011年第14期1091-1096,共6页Sheng Wang Zhigang Dai Xiwei Dong Suxiang Guo Yang Liu Shan Jiang Zhiping Wang 
the Natural Science Foundation of Shihezi University,No.RCZX200688
Recent research shows that the JNK1/2 signaling pathway plays a neuroprotective role against ischemia-reperfusion injury by cross-talk with other pathways.The present study investigated the effects of isoflurane and s...
关键词:population spikes HIPPOCAMPUS oxygen and glucose deprivation volatile anesthetic POSTCONDITIONING JNK1/2 neural regeneration 
Remote ischemia conditioning-an endogenous cardioprotective strategy from outside the heart被引量:8
《Chinese Medical Journal》2011年第14期2209-2215,共7页XIONG Jun LIAO Xu XUE Fu-shan YUAN Yu-jing WANG Qiang LIU Jian-hua 
;Fhis study was supported by a grant from the National Natural Science Foundation of China (No. 30972836).
Objective A general review was made of studies involving: (1) The experimental evidence of remote ischemic preconditioning (RIPC) and relative clinical studies, (2) The experimental and clinical evidences of re...
关键词:myocardial ischemic reperfusion injury ischemia preconditioning ischemia postconditioning remote preconditioning remote postconditioning 
Characterization of a critical role for CFTR chloride channels in cardioprotection against ischemia/ reperfusion injury被引量:9
《Acta Pharmacologica Sinica》2011年第6期824-833,共10页Sunny Yang XIANG Linda L YE Li-lu Marie DUAN Li-hui LIU Zhi-dong GE John A AUCHAMPACH Garrett J GROSS Dayue Darrel DUAN 
Aim: To further characterize the functional role of cystic fibrosis transmembrane conductance regulator (CFTR) in early and late (second window) ischemic preconditioning (IPC)- and postconditioning (POC)-medi...
关键词:ISCHEMIA PRECONDITIONING POSTCONDITIONING apoptosis cystic fibrosis transmembrane conductance regulator (CFTR) 
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