云南高校图书馆联盟文献共享服务平台- MICROSOME

MICROSOME: 作品数：16被引量：42H指数：4; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：李劲彤魏开华李敬来庄笑梅阮金秀更多>>; 相关机构：军事医学科学院肇庆学院华南师范大学更多>>; 相关期刊：《Molecular Plant》《Journal of Environmental Sciences》《分析测试学报》《Chinese Journal of Integrative Medicine》更多>>; 相关基金：国家自然科学基金国家高技术研究发展计划教育部留学回国人员科研启动基金更多>>

Enrichment of ER tubule-derived microsomes by differential centrifugation and immunoprecipitation: 《Biophysics Reports》2024年第2期61-66,共6页Yiduo Liu Junjie Hu Bing Yan; supported by grants from the National Key R&D Program of China(2021YFA1300800);Project for Young Scientists in Basic Research(YSBR-075)of the Chinese Academy of Sciences。; The endoplasmic reticulum(ER)is an essential component of the endomembrane system in eukaryotes and plays a crucial role in protein and lipid synthesis,as well as the maintenance of calcium homeostasis.Morphologically...; 关键词：Endoplasmic reticulum MICROSOME Differential centrifugation IMMUNOPRECIPITATION

Decreased exposure of simvastatin and simvastatin 3cid in a rat model of type 2 diabetes被引量：2: 《Acta Pharmacologica Sinica》2014年第9期1215-1225,共11页Dan XU Feng LI Mian ZHANG Ji ZHANG Can LIU Meng-yue HU Ze-yu ZHONG Ling-ling JIA Da-wei WANG Jie WU Li LIU Xiao-dong LIU; Aim： Simvastatin is frequently administered to diabetic patients with hypercholesterolemia. The aim of the study was to investigate the pharmacokinetics of simvastatin and its hydrolysate simvastatin acid in a rat mo...; 关键词：diabetes HYPERCHOLESTEROLEMIA SIMVASTATIN pharmacokinetics HEPATOCYTE MICROSOME CYP3A organic anion transporting polypeptide 2 multidrug resistance-associated protein 2 breast cancer resistance protein

A comparative study of influential factors correlating with early and late hypothyroidism after ^131I therapy for Graves＇ disease被引量：16: 《Chinese Medical Journal》2010年第12期1528-1532,共5页WANG Ren-fei TAN Jian ZHANG Gui-zhi MENG Zhao-wei ZHENG Wei; Background 131Ⅰ therapy is recognized as the simplest, safest, least expensive, and most effective treatment, and accepted by more and more patients. However its curative effect is influenced by many factors, therefo...; 关键词：Graves＇ disease ^131I therapy HYPOTHYROIDISM effective half-life time thyroid microsome antibody

Prevalence of antinuclear and anti-liver-kidney-microsome type-1 antibodies in patients with chronic hepatitis C in China被引量：9: 《Chinese Medical Journal》2009年第1期5-9,共5页BAI Li FENG Zhen-ru LU Hai-ying LI Wen-gang YU Min XU Xiao-yuan; Background Hepatitis C virus （HCV） infection may induce autoimmune response and autoantibodies can be detected in chronic hepatitis C （CHC） patients. However, the reported positive rate of autoantibodies in CHC pa...; 关键词：hepatitis C chronic AUTOANTIBODIES hepatitis autoimmune

Effects of two novel sugar drug candidates on CYP450 isoforms in different sexed Chinese human liver microsome in vitro: 《沈阳药科大学学报》2008年第S1期121-122,共2页SHI Jie,ZHANG Xin-hui,SU Jia-ru(Pharmacy Department of Qingdao Municipal Hospital,5 Donghai Road,Qingdao 266071,China); The sex-based differences between the effects of two novel sugar-based drug candidates,a sulfated polymannuroguluronate(SPMG-911)and an acidic oligosaccharide sugar chain compound(AOSC-971),on the enzymes CYP 1A2,CYP2...; 关键词：NOVEL SUGAR DRUG candidates CYP 450 enzymes human liver MICROSOME DRUG safety evaluation

New microsome-associated HT-family proteins from Nicotiana respond to pollination and define an HT/NOD-24 protein family被引量：1: 《Molecular Plant》2008年第4期634-644,共11页Katsuhiko Kondo Bruce McClure; HT-family proteins have been identified in Nicotiana, Solanum, and Petunia. HT-B-type proteins are implicated in S-RNase-based self-incompatibility, but the functions of other family members are unknown. Screening for...

Analysis of the Inhibitory Effect of Gypenoside on Na^+, K^+-ATPase in Rats' Heart and Brain and Its Kinetics被引量：6: 《Chinese Journal of Integrative Medicine》2007年第2期128-131,共4页韩晓燕卫洪波张富程; Supported by Guangdong Provincial Natural Science Foundation (No010742); Objective： To study the effects of gypenoside （Gyp） on the activity of microsomalNa^＋, K^＋-ATPase in rat＇s heart and brain in vitro. Methods： The microsomal Na^＋, K^＋-ATPase was prepared from rat＇s heart a...; 关键词：GYPENOSIDE Na^＋ K^＋-ATPase heart and brain microsome enzyme kinetic

Genotoxicity of vegetables irrigated by industrial wastewater: 《Journal of Environmental Sciences》2006年第5期964-968,共5页Nupur Mathur Pradeep Bhatnagar Hemraj Verma; Wastewater effluents from textile dyeing and printing industries of Sanganer are discharged directly, without any treatment, into Amani Shah Nallah drainage. The drainage water takes the dissolved toxicants to flora a...; 关键词：sanganer textile wastewaters MUTAGENICITY VEGETABLES Salmonella typhimurium： microsome bioassay

LC-MS检测肝微粒体孵育液中系列化合物被引量：1: 《分析测试学报》2004年第z1期70-71,共2页王海龙李劲彤庄笑梅李敬来魏开华阮金秀; 国家高技术研究发展课题资助项目(2003AA2Z3471); 　　肝脏是最重要的药物代谢器官之一,肝微粒体孵育试验可在亚细胞水平确定药物代谢稳定性、药酶抑制、活性代谢物生成等重要特性[1].对孵育液中药物进行定性定量检测是一项关键性试验,本文利用液相色谱-离子阱质谱技术,成功地对肝微粒...; 关键词：Ion trap mass spectrometry Hepatic microsome Qualitative analysis Quantitative analysis

Stereoselective propranolol metabolism in two drug induced rat hepatic microsomes被引量：4: 《World Journal of Gastroenterology》2000年第1期74-78,共5页Li X Zeng S; the National Natural Science Foundation of China,No.39370805.; AIM To study the influence of inducers BNFand PB on the stereoselective metabolism ofpropranolol in rat hepatic microsomes.METHODS Phase Ⅰ metabolism of propranololwas studied by using the microsomes induced byBNF an...; 关键词：Subject headings PROPRANOLOL enantiomers RAT HEPATIC MICROSOME PHENOBARBITAL β-naphthoflavone

MICROSOME