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Polypeptide nanoformulation-induced immunogenic cell death and remission of immunosuppression for enhanced chemoimmunotherapy被引量：6: 《Science Bulletin》2021年第4期362-373,M0004,共13页Xiangru Feng Weiguo Xu Jianhua Liu Di Li Gao Li Jianxun Ding Xuesi Chen; supported by the National Natural Science Foundation of China(51973216,51873207,51803006,51833010,51673190,and 51603204);the Science and Technology Development Program of Jilin Province(20200404182YY);the Youth Talents Promotion Project of Jilin Province(181909);the Youth Innovation Promotion Association of Chinese Academy of Sciences(2019005)。; Many conventional chemotherapeutics play an immune-modulating effect by inducing immunogenic cell death(ICD)in tumor cells.However,they hardly arouse strong antitumor immune response because the immunosuppressive lymp...; 关键词：Polypeptide nanogel Controlled drug release Immunogenic cell death Remission of Immunosuppression CHEMOIMMUNOTHERAPY

Fluorescence dynamics of N-terminal Trp–Trp residues in polypeptide: intrinsic indicators for monitoring p H: 《Science Bulletin》2015年第24期2129-2134,共6页Lei Li Hua Yi Mengfang Chang Xiaodan Cao Zhongneng Zhou Cuifang Qin Sanjun Zhang Haifeng Pan Yan Chen Jianhua Xu; supported by the National Natural Science Foundation of China(61108077;61178085);the Science and Technology Commission of Shanghai Municipality(15520711500;15ZR1411700);the Program of Introducing Talents of Discipline to Universities(B12024); pH plays a vital role in various cellular activities, and real-time observation of the intracellular p H through a p H indicator is very important for studying many physiological processes. In this paper, we studied t...; 关键词：Trp-Trp dipeptide FluorescenceIntrinsic pH sensors

A wound-induced small polypeptide gene family is upregulated in soybean nodules被引量：2: 《Chinese Science Bulletin》2013年第9期1003-1009,共7页LI XiaoLin XU Ji YU GuanQiao LUO Li; supported by National Key Basic Research Program of China(2011CB100702 and 2010CB126501);National Natural Science Foundation of China(31070218);Shanghai Municipal Natural Science Foundation(09ZR1436500);Knowledge Innovation Program of Chinese Academy of Sciences(2009KIP206); Small peptides function as key signals in processes,such as plant cell differentiation,organ development and defenses to biotic stresses.A large number of small peptide precursor genes have been predicted from the ana...; 关键词：基因家族大豆根瘤多肽创伤诱导蛋白质结构预测第6号染色体绿色荧光蛋白 12号染色体

Identification of AtSM34, a novel tonoplast intrinsic protein-interacting polypeptide expressed in response to osmotic stress in germinating seedlings被引量：3: 《Chinese Science Bulletin》2011年第33期3518-3530,共13页LI LiJuan REN Fei WEI PengCheng CHEN QiJun CHEN Jia WANG XueChen; supported by the National Natural Science Foundation of China (30770193);the National Basic Research Program of China (2006CB100100);the "111 Project" (B06003); Aquaporins are implicated in a wide variety of plant physiological processes, although the mechanisms involved in their regulation are not fully understood. To gain further insight into the regulatory factors involved...; 关键词：蛋白质相互作用渗透胁迫液泡膜幼苗多肽酵母双杂交系统组织化学染色鉴定

Suppression of murine breast cancer metastasis by selective inhibition of CXCR4 by synthetic polypeptide derived from viral macrophage inflammatory protein Ⅱ被引量：6: 《Chinese Science Bulletin》2010年第20期2152-2159,共8页YANG QingLin DING YongXing CHEN ChangJie TANG Jie ZHANG Ju YANG ZhiFeng; supported by the Natural Science Foundation of Anhui Province(070413119)and Clinical Testing and Diagnose Key Disciplines of Anhui Province; Stromal cell-derived factor-1 and its receptor CXC chemokine receptor-4(CXCR4)have been implicated in breast cancer metastasis.A significant association between HER2 and CXCR4 expression has been observed in human bre...; 关键词：选择性抑制 CXCR4 巨噬细胞乳腺癌合成肽小鼠蛋白病毒

Synthesis and micellization behavior of stimuli-responsive polypeptide hybrid triblock copolymer: 《Chinese Science Bulletin》2009年第11期1912-1917,共6页RAO JingYi ZHU ZhiYuan LIU ShiYong; Supported by the National Natural Science Foundation of China (Grant Nos.20534020, 20674079, and 20874092); Polypeptide hybrid triblock copolymer, poly(L-glutamic acid)-b-poly(propylene oxide)-b-poly (L-glu-tamic acid) (PLGA-b-PPO-b-PLGA), was synthesized by the ring-opening polymerization of benzyl-L-glutamic N-carboxyanhy...; 关键词：三嵌段共聚物胶束化行为混合多肽合成温度依赖性反应雷电定位系统

The effects of the synthetic nocistatin on blood vessel activities被引量：1: 《Chinese Science Bulletin》2001年第8期675-678,共4页Qiang Chen Yong Chen Lixiang Chen Dingjian Yang Shouliang Dong Rui Wang; the National NaturalScience Foundation of China (Grant No. 29972016) and the Natural Science Foundation of Gansu Province (Grant No. ZS 991-A23-056).; Nocistatin was synthesized by the solid-phase peptide synthesis method. Its effects on rat systemic arterial pressure; rat hindquarter vascular bed resistance; tension of rabbit pectoral, abdominal, femoral aorta musc...; 关键词：SOLID-PHASE POLYPEPTIDE synthesis NOCISTATIN NOCICEPTIN SYSTEMIC BLOOD pressure hindquarter vascular bed resistance BLOOD vessel muscle strip.

Relationship among Photosys-tem Ⅱ carbonic anhydrase,extrinsic polypeptides and manganese cluster被引量：2: 《Chinese Science Bulletin》2001年第5期406-409,共4页DAI Xinbin YU Yong ZHANG Rongxian YU Xinjian HE Peiming XU Chunhe; State Key Basic Research Development Plan (Grant No. G1998010100) and the National Natural Science Foundation of China (Grant No. 39770156).; Effects of Photosystem Ⅱ (PS Ⅱ) extrinsic polypeptides of oxygen-evolving complex and manganese clusters on PS Ⅱ carbonic anhydrase (CA) were studied with spinach PS Ⅱ membranes. The result supported that membrane...; 关键词：carbonic ANHYDRASE PS II oxygen evolution complex EXTRINSIC POLYPEPTIDE MANGANESE cluster.

Heterogeneity in photosystem Ⅰfrom Pisum sativum L.: 《Chinese Science Bulletin》1999年第1期58-62,共5页Zheng, CX Gao, RF; Studies have demonstrated that there are two types of PSI (PSI-1 and PSI-2) particles in some higher plants. These two types of PSI particles are proved to differ in organization and distribution on thylakoid membrane...; 关键词：PISUM sativum L. PHOTOSYSTEM I (PS I ) CHLOROPHYLL protein complexes POLYPEPTIDE composition HETEROGENEITY in PHOTOSYSTEM I .

Potential oscillations across oil-water interface in the presence of the biological surfactant and amino acids or polypeptides被引量：1: 《Chinese Science Bulletin》1998年第12期1008-1011,共4页Li Hexing Li Penghong Lu Jing; theNaturalScienceFoundationofShanghaiAcademicScience (BL95 0 0 1); A lot of potential oscillations across oil_water interface ahve been designed by using various surfactants and biological surfactants in the aqueous phase and various amino acids or even polypeptides in the oil phase ...; 关键词：OSCILLATIONS at liquid membrane AMINO acid POLYPEPTIDE surfactant.

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