云南高校图书馆联盟文献共享服务平台- DEACETYLASES

DEACETYLASES: 作品数：15被引量：61H指数：5; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：刘鸣赵蕊更多>>; 相关机构：哈尔滨医科大学附属第二医院苏州大学更多>>; 相关期刊：《Science China(Life Sciences)》《World Journal of Gastroenterology》《World Journal of Cardiology》《Advances in Microbiology》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划更多>>

Functions and mechanisms of plant histone deacetylases被引量：16: 《Science China(Life Sciences)》2020年第2期206-216,共11页Xiangsong Chen Adeline BDing Xuehua Zhong; Lysine acetylation, one of the major types of post-translational modifications, plays critical roles in regulating gene expression and protein function. Histone deacetylases(HDACs) are responsible for removing acetyl ...; 关键词：EPIGENETICS HISTONE DEACETYLASES development stress response PLANTS

DFT Study, Linear and Nonlinear Multiple Regression in the Prediction of HDAC7 Inhibitory Activities on a Series of Hydroxamic Acids: 《Computational Molecular Bioscience》2019年第3期63-80,共18页Doh Soro Lynda Ekou Bafétigué Ouattara Mamadou Guy-Richard Kone Tchirioua Ekou Nahossé Ziao; In this work, we conducted a QSAR study on 18 molecules using descriptors from the Density Functional Theory (DFT) in order to predict the inhibitory activity of hydroxamic acids on histone deacetylase 7. This study i...; 关键词：Hydroxamic ACIDS HISTONES DEACETYLASES DFT HISTONES DEACETYLASES Inhibitors QSAR

Role of the Putative Polysaccharide Deacetylase BA1836 from <i>B. anthracis</i>in Spore Development and Germination: 《Advances in Microbiology》2019年第8期679-702,共24页Anastasia Tomatsidou Dimitris Koutsioulis Dimitris Tzamarias Michael Kokkinidis Waldemar Vollmer Vassilis Bouriotis; Putative and known polysaccharide deacetylases (PDAs) from B. anthracis have key roles in resistance to host lysozyme, stabilization of the cell wall, biogenesis of peptidoglycan (PG) and for neutral polysaccharide mo...; 关键词：Bacillus ANTHRACIS POLYSACCHARIDE DEACETYLASES BA1836 Spores GERMINATION Spore Development

Histone deacetylases,microRNA and leptin crosstalk in pancreatic cancer被引量：2: 《World Journal of Clinical Oncology》2017年第3期178-189,共12页Cynthia I Tchio Mantho Adriana Harbuzariu Ruben R Gonzalez-Perez; Supported by NIH/NCI,No.1R41CA183399-01A1;Department of Defense(DoD) office of the Congressionally Directed Medical Research Programs(CDMRP),No.DODXWH-13-1-0382;the DOD W81XWH-13-1-0382;NIH/SBIR1R41CA183399-01A1;Pilot Project Award from MSM/Tuskegee University/UAB Cancer Center Partnership grant 5U54CA118638;PC SPORE Grant from UAB to RRGP;National Institute on Minority Health and Health Disparities(NIMHD)of NIH under award number 5S21MD00101;facilities and support services at MSM(1G12RR026250-03;NIH RR 03034 and 1C06 RR18386);The Calvin Johnson Jr.Foundation Pancreatic Cancer Research Scholarship to Cynthia I Tchio Mantho; Because pancreatic cancer(PC) historically has had poor prognosis and five year survival rates,it has been intensely investigated.Analysis of PC incidence and biology has shown a link between different risk factors su...; 关键词：PANCREATIC CANCER MICRORNA HISTONE DEACETYLASES PANCREATIC CANCER stem cell markers LEPTIN Obesity

Novel epigenetic-based therapies useful in cardiovascular medicine被引量：5: 《World Journal of Cardiology》2016年第2期211-219,共9页Claudio Napoli Vincenzo Grimaldi Maria Rosaria De Pascale Linda Sommese Teresa Infante Andrea Soricelli; Epigenetic modifications include DNA methylation, his-tone modifications, and micro RNA. Gene alterations have been found to be associated with cardiovascular diseases, and epigenetic mechanisms are continuously being...; 关键词：EPIGENETICS Cardiovascular diseases Heart failure Inhibitors of HISTONE DEACETYLASES ANTISENSE microRNAs

Tetrahydroisoquinolines as novel histone deacetylase inhibitors for treatment of cancer被引量：4: 《Acta Pharmaceutica Sinica B》2016年第1期93-99,共7页Danqi Chen Aijun Shen Guanghua Fang Hongchun Liu Minmin Zhang Shuai Tang Bing Xiong Lanping Ma Meiyu Geng Jingkang Shen; supported financially by the National Science & Technology Major Project ‘Key New Drug Creation and Manufacturing Program’ of China(Grant No.2014ZX09507002);the National Marine ‘863’ Project(No.2013AA092902); Histone acetylation is a critical process in the regulation of chromatin structure and gene expression.Histone deacetylases(HDACs)remove the acetyl group,leading to chromatin condensation and transcriptional repressio...; 关键词：HISTONE DEACETYLASES INHIBITOR ANTICANCER TETRAHYDROISOQUINOLINE Structure–activity relationship

Essential roles of four-carbon backbone chemicals in the control of metabolism: 《World Journal of Biological Chemistry》2015年第3期223-230,共8页Sabrina Chriett Luciano Pirola; The increasing incidence of obesity worldwide and its related cardiometabolic complications is an urgent public health problem. While weight gain results from a negative balance between the energy expenditure and calo...; 关键词：Butyric acid Dβ-hydroxybutyrate HISTONE DEACETYLASES HISTONE DEACETYLASES INHIBITORS INSULIN resistance

Protein deacetylases and axonal regeneration: 《Neural Regeneration Research》2015年第6期870-871,共2页Fanny Ng Bor Luen Tang; supported by the Graduate School for Integrative Sciences and Engineering,National University of Singapore; A neuron with injured or severed axon responds with attempts at axonal regrowth. In this regard, axonal regeneration of peripheral nerves occurs far more efficiently compared to central nervous system （CNS） neurons....

Histone deacetylases and cardiovascular cell lineage commitment被引量：2: 《World Journal of Stem Cells》2015年第5期852-859,共8页Jun-Yao Yang Qian Wang Wen Wang Ling-Fang Zeng; Supported by British Heart Foundation project,No.PG13-63-30419; Cardiovascular diseases(CVDs), which include alldiseases of the heart and circulation system, are the leading cause of deaths on the globally. During the development of CVDs, choric inflammatory, lipid metabolism diso...; 关键词：HISTONE DEACETYLASES Stem CELL ENDOTHELIALCELL Smooth muscle CELL CARDIOVASCULAR diseases

组蛋白脱乙酰化酶及其抑制剂在头颈部肿瘤中的研究: 《国际耳鼻咽喉头颈外科杂志》2013年第6期350-352,共3页赵蕊刘鸣; 组蛋白脱乙酰化酶（histonc deacetylases，HDACs）是使组蛋白去乙酰化从而抑制基因转录的一类蛋白酶，参与维持组蛋白乙酰化与去乙酰化的平衡状态，对肿瘤的发生发展起重要作用，正常细胞一旦发生核内组蛋白乙酰化与去乙酰化的失衡，...; 关键词：组蛋白脱乙酰基酶类(Histone Deacetylases) 头颈部肿瘤(Head and NECK Neoplasms)

DEACETYLASES