GLYCOALKALOIDS

作品数：16被引量：17H指数：3
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相关领域：农业科学生物学更多>>
相关期刊：《Journal of Integrative Agriculture》《Horticultural Plant Journal》《Molecular Horticulture》《Journal of Chinese Pharmaceutical Sciences》更多>>
相关基金：国家自然科学基金更多>>
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Finding the balance: Modifying the cholesterol and steroidal glycoalkaloid synthesis pathway in tomato(Solanum lycopersicum L.) for human health, fruit flavor, and plant defense
《Horticultural Plant Journal》2025年第1期42-56,共15页Vincenzo Averello IV Adrian D.Hegeman Changbin Chen 
Unlike most plants, members of the genus Solanum produce cholesterol and use this as a precursor for steroidal glycoalkaloids. The production of the compounds begins as a branch from brassinosteroid biosynthesis, whic...
关键词：CHOLESTEROL Steroidal glycoalkaloids TOMATO Biosynthesis a-tomatine STEROLS TERPENOIDS Plant defense 
From steroidal glycoalkaloids to steroidal saponins:Biosynthesis and ecological role in the Solanum genus
《Molecular Plant》2025年第1期22-24,共3页Yan Li Jie Luo 
funded by grants from the National Natural Science Foundation of China(32100213);the Project of Sanya Yazhou Bay Science and Technology City(SCKJ-JYRC-2023-18);the Hainan Provincial Natural Science Foundation of China(222RC553,323RC423);the Hainan University Collaborative Innovation Center of Nanfan and High-Efficiency Tropical Agriculture(XTCX2022NYC09);the Hainan University Startup Fund(RZ2100003223).
Solanaceae plants produce two major classes of valuable steroid-derived specialized metabolites:steroidal glycoalkaloids(SGAs)and steroidal saponins(STSs)(Grzech et al.,2025).SGAs are crucial in plant defense despite ...
关键词：steroidal ALKALOIDS SAPONINS 
Steroidal scaffold decorations in Solanum alkaloid biosynthesis被引量：1
《Molecular Plant》2024年第8期1236-1254,共19页Rosalind Lucier Mohamed O.Kamileen Yoko Nakamura Sofiia Serediuk Ranjit Barbole Jens Wurlitzer Maritta Kunert Sarah Heinicke Sarah E.O'Connor Prashant D.Sonawane 
the Fulbright Us Student Program,which is sponsored by The US Department of State and the German-American Fulbright Commission.We thank Prof.M.Court for UGT nomenclature assignment.N.benthamiana and green unripe and purple ripe S.nigrum berries used in the main and supplementary figures were generated in BioRender.We kindly acknowledge the Max Planck Society and the European Research Council(788301)for funding.
Steroidal glycoalkaloids(SGAs)are specialized metabolites produced by hundreds of Solanum species,including important vegetable crops such as tomato,potato,and eggplant.Although it has been known that SGAs play import...
关键词：steroidal glycoalkaloids SOLANUM biosynthetic pathway α-solamargine malonyl-solamargine specialized metabolites 
Glycoalkaloids:Structural diversity and pharmacological activities
《Guideline and Standard in Chinese Medicine》2024年第2期44-61,共18页Yuelin Jia Guiyang Xia Lingyan Wang Huan Xia Xiaohong Wei Sheng Lin 
supported by the National Natural Science Foundation of China(No.82073978);the Fundamental Research Funds for the Central Universities(No.2023-JYBJBZD-048 and 2022-JYB-JBZR-015).
Glycoalkaloids(GAs)are a class of special secondary metabolites found in plants.Studies have found that they have a wide range of pharmacological activities,such as antiviral,antifungal,and anticancer properties,with ...
关键词：GLYCOALKALOIDS water-soluble extract separation methods 
Potato steroidal glycoalkaloids:properties,biosynthesis,regulation and genetic manipulation
《Molecular Horticulture》2024年第1期2-16,共15页Yongming Liu Xiaowei Liu Yingge Li Yanfei Pei Abdul Jaleel Maozhi Ren 
supported by the National Natural Science Foundation of China(32202567);National Key Research and Development Program of China(2023YFE0199400);Sichuan Science and Technology Program(2022NSFSC1754,2023YFQ0100);Central Public-Interest Scientific Institution Basal Research Fund(S2022003).
Steroidal glycoalkaloids(SGAs),predominantly comprisingα-solanine(C_(45)H_(73)NO_(15))andα-chaconine(C_(45)H_(73)NO_(14)),function as natural phytotoxins within potatoes.In addition to their other roles,these SGAs a...
关键词：POTATO Steroidal glycoalkaloids Antinutritional factors BIOSYNTHESIS Regulation network Quality improvement TOXICITY 
Unique Clinical Features of Curaderm when Treating Skin Cancers
《Journal of Cancer Therapy》2024年第1期13-27,共15页Tania Robyn Chase Kai Elliot Cham Bill Elliot Cham 
Basal cell carcinoma is the most common form of skin cancer and the most frequently occurring form of all cancers. Conventional treatments to remove or destroy basal cell carcinoma are indiscriminate and also remove o...
关键词：Curaderm Skin Cancer Basal Cell Carcinoma BEC GLYCOALKALOIDS Conventional Treatments 
Three previously undescribed steroidal glycoalkaloids from Solanum lyratum and their anti-tumor activities被引量：1
《Journal of Chinese Pharmaceutical Sciences》2022年第3期192-201,共10页Liangyu Liu Yuke Yang Xiao Du Tong Wu Jiannong Wang 
National Natural Science Foundation of China(Grant No.81872989).
In the present study,three previously undescribed steroidal glycoalkaloids(compounds 1–3)were isolated from Solanum lyratum.Their structures were elucidated based on comprehensive spectroscopic data.Their anti-angiog...
关键词：Solanum lyratum Steroidal glycoalkaloids ANTI-TUMOR METASTASIS ANGIOGENESIS 
Two new glycoalkaloids from Solanum lyratum Thunb.
《Journal of Chinese Pharmaceutical Sciences》2021年第6期518-523,共6页Tong Wu Xiao Du Jiannong Wang Liangyu Liu Yuke Yang 
National Natural Science Foundation of China(Grant No. 81872989);the Program of G20 Project Support Guarantee(Grant No. Z151100003815026);the National Major New Drugs Inn ovation Projects (Grant No. 2009ZX09103-402)。
To study the alkaloids of Solanum lyratum Thunb.ODS and silica gel column chromatography combined with HPLC were used to separate and purify the alkaloids.Seven alkaloids were identified via UHPLC-ESI-Q-TOF-MS,1 D and...
关键词：Solanum lyratum Thunb. Steroidal glycoalkaloids Chemical constituents Structure identification 
Inheritance of steroidal glycoalkaloids in potato tuber flesh被引量：1
《Journal of Integrative Agriculture》2019年第10期2255-2263,共9页PENG Zhen WANG Pei TANG Die SHANG Yi LI Can-hui HUANG San-wen ZHANG Chun-zhi 
supported by the Agricultural Science and Technology Innovation Program from the Chinese Academy of Agricultural Sciences(ASTIP-CAAS);the Agricultural Science and Technology Innovation Program Cooperation and Innovation Mission,CAAS(CAAS-XTCX2016);the Advanced Technology Talents in Yunnan Province,China 2013HA025);the PhD Scholar Newcomer Award in Yunnan Province,China(01701205020516025);the Graduate Research and Innovation Fund Project,China(yjs201679);supported by the Ministry of Agriculture and Rural Affairs of China,the Shenzhen Municipal and Dapeng District Governments,China
Potato (Solanum tuberosum L.) is the third most important food crop worldwide after wheat and rice in terms of human consumption. A critical domestication trait for potato was the decrease of toxic steroidal glycoalka...
关键词：steroidal GLYCOALKALOIDS DOMESTICATION TUBER FLESH QTL mapping 
Glycoalkaloids and phenolic compounds in three commercial potato cultivars grown in Hebei,China被引量：4
《Food Science and Human Wellness》2018年第2期156-162,共7页Cheng-Yu Jin Hong Liu Dan Xu Fan-Kui Zeng Yu-Ci Zhao Hai Zhang Gang Liu 
This work was supported by the China Agriculture Research System(CARS-10);the National Key Research and Development Plan(2016YFD0401302-02);the Science and Technology Major Project of Gansu Province(1602NKDJ022-1);the Natural Science Foundation of Gansu Province(1501RJZA004);the Science and Technology Planing Project of Lanzhou(2016-3-123).
In order to investigate the food nutrition and safety of potato,the objective of the present study is to quantify glycoalkaloids(-chaconine and-solanine)and phenolic compounds in three potato cultivars,namely,Russet B...
关键词：GLYCOALKALOIDS Phenolic compounds Dehydrated potato flake POTATO 
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