Nitric oxide(NO)is a gaseous molecule produced by 3 different NO synthase(NOS)isoforms:Neural/brain NOS(nNOS/bNOS,type 1),endothelial NOS(eNOS,type 3)and inducible NOS(type 2).Type 1 and 3 NOS are constitutively expre...
supported by the National Key R&D Program of China,No.2019YFE0121200(to LQZ);the National Natural Science Foundation of China,Nos.82325017(to LQZ),82030032(to LQZ),82261138555(to DL);the Natural Science Foundation of Hubei Province,No.2022CFA004(to LQZ);the Natural Science Foundation of Jiangxi Province,No.20224BAB206040(to XZ);Research Project of Cognitive Science and Transdisciplinary Studies Center of Jiangxi Province,No.RZYB202201(to XZ).
With an increase in global aging,the number of people affected by cerebrovascular diseases is also increasing,and the incidence of vascular dementia-closely related to cerebrovascular risk-is increasing at an epidemic...
The endothelium modulates vascular homeostasis owing to a variety of vasoconstrictors and vasodilators.Endothelial dysfunction(ED),characterized by impaired vasodilation,inflammation,and thrombosis,triggers future car...
supported by the National Natural Science Foundation of China(22302100,22025203,22121005);the Fundamental Research Funds for the Central Universities(Nankai University).
As a prominent contributor to air pollution,nitric oxide(NO)has emerged as a critical agent causing detrimental environmental and health ramifications.To mitigate emissions and facilitate downstream utilization,adsorp...
supported by the Russian Science Foundation grant(No.22-15-00120);supported by the grant(No.21-2-10-59-1)from the Foundation for the Development of Theoretical Physics and Mathematics BASIS.
Red blood cell(RBC)aggregation as well as their deformation significantly affects blood microrheology.These processes depend on various factors,one of which is concentration of the nitric oxide,one of the main signali...
supported by the Russian Science Foundation Grant No.22-15-00120.
Red blood cells(RBCs)are the most abundant human blood cells.RBC aggregation and deformation strongly determine blood viscosity which impacts hemorheology and microcirculation.In turn,RBC properties depend on di®erent...
Background:Resveratrol is a non-flavonoid polyphenol that shows promise in reducing proinflammatory factors and maintaining endothelial function,which hints at its potential role in slowing atherosclerosis and prevent...
Real-time and accurate monitoring of vital biomarkers in vivo forms a crucial foundation for health assessment,early intervention,and disease treatment.Specifically,continuous monitoring of intracranial nitric oxide(N...
supported by the National Key Research and Development Program of China (2022YFB3807300);the National Natural Science Foundation of China (51933009,82370427,22305219);the Fundamental Research Funds for the Central Universities,China (26-2023-00074);the Natural Science Foundation of Zhejiang Province,China (No.LY20H020005);The Zhejiang Provincial Traditional Chinese Medicine Science and Technology Plan,China (2022ZX012);The Province and Central Administration-Zhejiang Provincial Health Commission,China (WKJ-ZJ-2209).
Vascular diseases seriously threaten human life and health.Exogenous delivery of nitric oxide(NO)represents an effective approach for maintaining vascular homeostasis during pathological events.However,the overproduct...
the financial support from the National Natural Science Foundation of China (No. 82372019, 82022034, 82173327);Jiangsu Province Natural Science Foundation of China (BK20200032);Double First Class Foundation of China Pharmaceutical University(CPUQNJC22_03)
Photothermal and photodynamic therapies(PTT/PDT)hold promise for localized tumor treatment,yet their full potential is hampered by limitations such as the hypoxic tumor microenvironment and inadequate systemic immune ...