PARKINSON_DISEASE

作品数:123被引量:198H指数:7
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相关作者:余舒扬陈滢陈晓春王涛张巧俊更多>>
相关机构:首都医科大学附属北京天坛医院福建医科大学环境与疾病相关基因教育部重点实验室西安交通大学更多>>
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相关基金:国家自然科学基金北京市自然科学基金国家重点基础研究发展计划陕西省自然科学基金更多>>
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Effects of acupuncture on SATB1/p21 signaling pathway and SASPs in MPTP-induced Parkinson disease model mice
《Journal of Acupuncture and Tuina Science》2025年第1期1-11,共11页LI Guona ZHAO Chen WANG Zhaoqin HUA Xuegui WU Luyi ZHANG Xiyin SHEN Lin CHEN Ziyi HU Wenqing CHEN Yiyi CHENG Ling QIAO Yu 
国家中医药管理局高水平中医药重点学科建设项目,No.zyyzdxk-2023068;国家自然科学基金项目,No.82205260;上海市浦东新区卫计委名中医培养计划,No.PWRzm2020-12;浦东新区卫计委学科建设中医针灸重点专科,No.PWZzk2022-25.
Objective:To observe the effects of acupuncture on the motor function of Parkinson disease(PD)model mice and to investigate the neuroprotective effects of acupuncture on PD from the perspective of cellular senescence....
关键词:Acupuncture Therapy Point Baihui(GV20) Point Yanglingquan(GB34) Parkinson Disease Signal Transduction Cell Aging Mice 
Multi-omics analysis reveals the neuroprotective effect of Atractylodis Rhizoma Alba extract against Parkinson's disease in mouse
《Journal of Traditional Chinese Medicine》2024年第6期1111-1117,共7页KANG Sohi LEE Soong-In MOON Byeong Cheol SONG Jun Ho KIM Sung-Ho MOON Changjong LEE Sueun KIM Chul KIM Joong Sun 
the Development of Sustainable Application for Standard Herbal Resource by the Korea Institute of Oriental Medicine (No. KSN2012320)。
OBJECTIVE: To assess Atractylodis Rhizoma Alba extract(ARE) neuroprotective function in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-treated mice and related genes. METHODS: Examined m RNA-DNA methylation change...
关键词:Parkinson disease nerve degeneration 1-methyl-4-phenyl-1 2 3 6-TETRAHYDROPYRIDINE Atractylodis Rhizoma Alba Methyl-seq 
Investigating efficacy mechanism of electroacupuncture in treating Parkinson disease through TMT proteomics
《Journal of Acupuncture and Tuina Science》2024年第6期470-481,共12页ZHU Lu LI Guona WU Pin WU Luyi SHEN Lin QIAO Yu LI Jing LI Lingjie WANG Zhaoqin CHEN Yiyi MA Xiaopeng LI Kunshan WU Huangan 
上海市老龄化和妇儿健康研究专项,No.2020YJZX0134;国家自然科学基金青年科学基金项目,No.82205260;上海市科学技术委员会科研计划项目,No.18401970700;上海市卫生健康委员会科研课题,No.20204Y0271;国家中医药管理局高水平中医药重点学科(针灸学)建设项目,No.ZYYZDXK-2023068.
Objective:To explore the therapeutic mechanism of electroacupuncture(EA)in treating Parkinson disease(PD)using Tandem mass tag(TMT)quantitative proteomics technology.Methods:Forty-eight PD patients were randomly divid...
关键词:Acupuncture Therapy ELECTROACUPUNCTURE PROTEOMICS Tandem Mass Spectrometry Cyclic AMP Parkinson Disease 
Effectivenss of electroacupuncture for skeletal muscle pain in Parkinson's disease:a Clinical randomized controlled trial被引量:1
《Journal of Traditional Chinese Medicine》2024年第2期388-395,共8页WANG Shaosong SUN Jingqing FENG Qingyin LI Bin WANG Xin YUAN Fan CUI Yingxue 
the Project of National Famous Old Chinese Medicine Experts Inheritance Studio Construction:the National Project of Taking Inheriting Experience of Prestigious Chinese Physicians Wang Linpeng(No.ZY202275)。
OBJECTIVE:To explore the effect of electroacupuncture on skeletal muscle pain in Parkinson's disease(PD).METHODS:A single-center randomized controlled trial was conducted with sixty patients with Parkinson's disease w...
关键词:Parkinson disease MUSCLE SKELETAL PAIN ELECTROACUPUNCTURE muscle tention mood disorders randomized controlled trial 
Protective effect of Tongdu Tiaoshen acupuncture combined with Xiaoxuming decoction(小续命汤)on dopaminergic neurons in Parkinson’s disease model被引量:4
《Journal of Traditional Chinese Medicine》2023年第3期484-493,共10页WU Haiyang WANG Ying HAN Wei LI Huihui JI Haisheng LIU Xiuxiu 
Supported by National Natural Science Foundation of China:Study on the Mechanism of Regulating miR-124 by Tongdu Tiaoshen Acupuncture to Promote Neuroprotection in Cerebral Ischemia Reperfusion Injury(No.81973933);Natural Science Fund for Colleges and Universities in Anhui Province:Study on the Regulatory Mechanism of Tongdu Tiaoshen Acupuncture on Dopaminergic Neurons in Parkinson’s Disease Model Mice Based on Mitochondrial Autophagy(No.KJ2019A0475)。
OBJECTIVE:To explore the possible mechanism of Tongdu Tiaoshen acupuncture combined with Xiaoxuming decoction(小续命汤,XXMD)in the treatment of Parkinson’s disease(PD).METHODS:C57BL/6 mice were randomly divided into ...
关键词:Parkinson disease ACUPUNCTURE dopaminergic neurons Tongdu Tiaoshen Xiaoxuming decoction mitochondrial autophagy 
Effect of electroacupuncture for Pisa syndrome in Parkinson’s disease:A case report
《World Journal of Clinical Cases》2022年第30期11023-11030,共8页Wei-Jing Lu Jing-Qi Fan Ming-Yue Yan Keiko Mukaeda Li-Xing Zhuang Li-Li Wang 
Supported by National Natural Science Foundation of China,No.82174486。
BACKGROUND Pisa syndrome(PS)refers to marked lateral flexion of the trunk with a Cobb angle greater than 10°,which is typically mobile and can be resolved by lying down.PS is one of the most common postural deformiti...
关键词:Pisa syndrome SCOLIOSIS Parkinson disease ELECTROACUPUNCTURE Postural deformities Case report 
Improvement effect of acupuncture on locomotor function in Parkinson disease via regulating gut microbiota and inhibiting inflammatory factorrelease被引量:3
《Journal of Acupuncture and Tuina Science》2022年第5期339-353,共15页Qiang WANG Yuan WANG LIU Zhibin GUO Jie LI Jie ZHAO Yingqian 
陕西省自然科学基础研究计划,No.2020JM594,No.2017JM8108。
Objective To observe the effect of acupuncture on the intestinal flora in Parkinson disease(PD)model mice and explore the mechanism of acupuncture in improving the locomotor function in PD.Methods Thirty-two C57BL/6 m...
关键词:Acupuncture Therapy Parkinson Disease Neurologic Manifestations Gastrointestinal Microbiome Tumor Necrosis Factor Mice 
Protective effect of resveratrol on rat cardiomyocyte H9C2 cells injured by hypoxia/reoxygenation by regulating mitochondrial autophagy via PTEN-induced putative kinase protein 1/Parkinson disease protein 2 signaling pathway被引量:3
《Journal of Traditional Chinese Medicine》2022年第2期176-186,共11页ZHAO Lixia SUN Wei BAI Decheng 
Supported by the Open Fund of Key Laboratory of Dunhuang Medicine,Ministry of Education(DHYX20-09);the Youth Research Foundation of the Gansu University of Chinese Medicine(No.ZQ2017-14)。
OBJECTIVE:To investigate the protective effect of resveratrol on cardiomyocytes after hypoxia/reoxygenation intervention based on PTEN-induced putative kinase protein 1/Parkinson disease protein 2(PINK1/PARKIN)signali...
关键词:RESVERATROL MYOCYTES cardiac hypoxia PTEN phosphohydrolase Parkinson disease associated proteins mitochondrial autophagy 
Effect of Roucongrong(Herba Cistanches Deserticolae) decoction on the substantia nigra through Wnt/β-catenin signaling pathway in rats with Parkinson's disease induced by 6-hydroxydopamine hydrochloride被引量:4
《Journal of Traditional Chinese Medicine》2021年第5期762-770,共9页XU Qian QIN Wei WU Fangzhen LIN Yao HONG Liting CHEN Dan HU Xuefeng CAI Jing 
Supported by the Creation of Major New Drugs for Major National Science and Technology Projects(No.2019ZX09301154);National Natural Science Foundation of China(Nos.81904263,81804156);2021 Fujian Provincial Traditional Chinese Medicine Science and Technology Program;2018 Outstanding Young Scientific Research Project in Fujian province。
OBJECTIVE:To investigate the effect of Roucongrong(Herba Cistanches Deserticolae)decoction on the substantia nigra in rats with Parkinson’s disease(PD)induced by 6-hydroxydopamine hydrochloride(6-OHDA).To further det...
关键词:CISTANCHE Parkinson disease SURVIVAL tyrosine 3-monooxygenase Wnt signaling pathway 
Research progress in mechanism of curcumin in treatment of Parkinson disease
《中国药理学与毒理学杂志》2021年第10期776-777,共2页YUAN Xin-ru JING Yong-shuai ZHANG Dan-shen 
Key Research and Development Program of Hebei Province(20370509D);and Science and Technology Project of Hebei Education Department(ZD2020117)。
Curcumin(Cur)is an important bioactive component of polyphenols in the rhizomes of Curcuma longa L.,Tulipa gesneriana L.and other Curcuma plants.It has a wide range of pharmacological effects such as anti-tumor,anti-a...
关键词:CURCUMIN Parkinson disease mechanism of action 
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