云南高校图书馆联盟文献共享服务平台- PARKINSON

PARKINSON_DISEASE: 作品数：123被引量：198H指数：7; 导出分析报告; 相关作者：余舒扬陈滢陈晓春王涛张巧俊更多>>; 相关机构：首都医科大学附属北京天坛医院福建医科大学环境与疾病相关基因教育部重点实验室西安交通大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金北京市自然科学基金国家重点基础研究发展计划陕西省自然科学基金更多>>

Multi-omics analysis reveals the neuroprotective effect of Atractylodis Rhizoma Alba extract against Parkinson's disease in mouse: 《Journal of Traditional Chinese Medicine》2024年第6期1111-1117,共7页KANG Sohi LEE Soong-In MOON Byeong Cheol SONG Jun Ho KIM Sung-Ho MOON Changjong LEE Sueun KIM Chul KIM Joong Sun; the Development of Sustainable Application for Standard Herbal Resource by the Korea Institute of Oriental Medicine (No. KSN2012320)。; OBJECTIVE: To assess Atractylodis Rhizoma Alba extract(ARE) neuroprotective function in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-treated mice and related genes. METHODS: Examined m RNA-DNA methylation change...; 关键词：Parkinson disease nerve degeneration 1-methyl-4-phenyl-1 2 3 6-TETRAHYDROPYRIDINE Atractylodis Rhizoma Alba Methyl-seq

Protective effect of Tongdu Tiaoshen acupuncture combined with Xiaoxuming decoction(小续命汤)on dopaminergic neurons in Parkinson’s disease model被引量：4: 《Journal of Traditional Chinese Medicine》2023年第3期484-493,共10页WU Haiyang WANG Ying HAN Wei LI Huihui JI Haisheng LIU Xiuxiu; Supported by National Natural Science Foundation of China:Study on the Mechanism of Regulating miR-124 by Tongdu Tiaoshen Acupuncture to Promote Neuroprotection in Cerebral Ischemia Reperfusion Injury(No.81973933);Natural Science Fund for Colleges and Universities in Anhui Province:Study on the Regulatory Mechanism of Tongdu Tiaoshen Acupuncture on Dopaminergic Neurons in Parkinson’s Disease Model Mice Based on Mitochondrial Autophagy(No.KJ2019A0475)。; OBJECTIVE:To explore the possible mechanism of Tongdu Tiaoshen acupuncture combined with Xiaoxuming decoction(小续命汤,XXMD)in the treatment of Parkinson’s disease(PD).METHODS:C57BL/6 mice were randomly divided into ...; 关键词：Parkinson disease ACUPUNCTURE dopaminergic neurons Tongdu Tiaoshen Xiaoxuming decoction mitochondrial autophagy

Protective effect of resveratrol on rat cardiomyocyte H9C2 cells injured by hypoxia/reoxygenation by regulating mitochondrial autophagy via PTEN-induced putative kinase protein 1/Parkinson disease protein 2 signaling pathway被引量：3: 《Journal of Traditional Chinese Medicine》2022年第2期176-186,共11页ZHAO Lixia SUN Wei BAI Decheng; Supported by the Open Fund of Key Laboratory of Dunhuang Medicine,Ministry of Education(DHYX20-09);the Youth Research Foundation of the Gansu University of Chinese Medicine(No.ZQ2017-14)。; OBJECTIVE:To investigate the protective effect of resveratrol on cardiomyocytes after hypoxia/reoxygenation intervention based on PTEN-induced putative kinase protein 1/Parkinson disease protein 2(PINK1/PARKIN)signali...; 关键词：RESVERATROL MYOCYTES cardiac hypoxia PTEN phosphohydrolase Parkinson disease associated proteins mitochondrial autophagy

Effect of Roucongrong(Herba Cistanches Deserticolae) decoction on the substantia nigra through Wnt/β-catenin signaling pathway in rats with Parkinson's disease induced by 6-hydroxydopamine hydrochloride被引量：4: 《Journal of Traditional Chinese Medicine》2021年第5期762-770,共9页XU Qian QIN Wei WU Fangzhen LIN Yao HONG Liting CHEN Dan HU Xuefeng CAI Jing; Supported by the Creation of Major New Drugs for Major National Science and Technology Projects(No.2019ZX09301154);National Natural Science Foundation of China(Nos.81904263,81804156);2021 Fujian Provincial Traditional Chinese Medicine Science and Technology Program;2018 Outstanding Young Scientific Research Project in Fujian province。; OBJECTIVE:To investigate the effect of Roucongrong(Herba Cistanches Deserticolae)decoction on the substantia nigra in rats with Parkinson’s disease(PD)induced by 6-hydroxydopamine hydrochloride(6-OHDA).To further det...; 关键词：CISTANCHE Parkinson disease SURVIVAL tyrosine 3-monooxygenase Wnt signaling pathway

Research progress in mechanism of curcumin in treatment of Parkinson disease: 《中国药理学与毒理学杂志》2021年第10期776-777,共2页YUAN Xin-ru JING Yong-shuai ZHANG Dan-shen; Key Research and Development Program of Hebei Province(20370509D);and Science and Technology Project of Hebei Education Department(ZD2020117)。; Curcumin(Cur)is an important bioactive component of polyphenols in the rhizomes of Curcuma longa L.,Tulipa gesneriana L.and other Curcuma plants.It has a wide range of pharmacological effects such as anti-tumor,anti-a...; 关键词：CURCUMIN Parkinson disease mechanism of action

Epigenetic mechanisms involved in the neuroprotective effect of scorpion extract in a Parkinson's disease murine model based on multi-omics approach被引量：2: 《Journal of Traditional Chinese Medicine》2021年第3期390-396,共7页Joong Sun Kim Hye-Sun Lim Byeong Cheol Moon Mary Jasmin Ang Sung-Ho Kim Changjong Moon Boseok Seong Yunji Jang Hyung-Yong Kim Chul Kim; Supported by the Korea Institute of Oriental Medicine:the Verification of Efficacy and Safety for Chung-bu Medicinal Materials Described in the Dong Ui Bo Gam (K18411);Applicational Development of Standardized Herbal Resources (KSN1911420)。; OBJECTIVE: To investigate whether scorpion extract elicits a neuroprotective effect in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-treated mice models, and the genes associated with the therapeutic effects usin...; 关键词：SCORPIONS 1-methyl-4-phenyl-1 2 3 6-TETRAHYDROPYRIDINE Parkinson disease DNA methylation

Chemical constituents isolated from the aerial parts of Swertia pseudochinensis and their potential neuroprotective effects被引量：2: 《Acupuncture and Herbal Medicine》2021年第1期59-64,共6页Ke Xiang Qi He Yanmei Chen Dongxin Yang Yanwei Duan Hua Li Lixia Chen; financially supported by the Liaoning Revitalization Talents Program(No.XLYC1807182);the Liaoning Province Natural Science Foundation(No.2019-MS-299).; Objective:Swertia pseudochinensis,an annual herb of the genus Swertia in the family Gentianaceae.Some constituents and extracts from the Swertia genus have been recently reported to possess neuroprotective effects,sug...; 关键词：ANTHRAQUINONE Neuroprotective effect Parkinson disease Swertia pseudochinensis XANTHONE

Neuroprotective effects of Suhexiang Wan on the in vitro and in vivo models of Parkinson’s disease被引量：5: 《Journal of Traditional Chinese Medicine》2019年第6期800-808,共9页Liu Quanfeng Sang Heon Kim Yung-Wei Sung Sok Cheon Pak Wonwoong Lee Jongki Hong Jaehwan Jang Kyoung Sang Cho Songhee Jeon Byung-Soo Koo; Supported by the Dongguk University Research Fund of 2014; OBJECTIVE:To examine the role of KSOP1009(a modified formulation of Suhexiang Wan essential oil)in an animal model of Parkinson's disease(PD)induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydro-pyridine(MPTP)injection.METH...; 关键词：Parkinson disease 1-methyl-4-phenyl-1 2 3 6-tetrahydropyridine Mitochondria Reactive oxygen species Suhexiang Wan

Ginsenoside Rg1 attenuates motor impairment and neuroinflammation in the MPTP-probenecid-induced parkinsonism mouse model: 《中国药理学与毒理学杂志》2017年第10期999-1000,共2页Qian-hang SHAO Yu-he YUAN Nai-hong CHEN; supported by National Natural Science Foundation of China(81274122,81373997,U1402221,81573640,81273629);Beijing Natural Science Foundation(7131013);Specialized Research Fund for the Doctoral Program of Higher Education of China(20121106130001);Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study(BZ0150); OBJECTIVE To evaluate these activities of Rg1 in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)/probenecid(MPTP/p)-induced PD mouse model for the first time and to elucidate the underlying mechanisms.METHODS M...; 关键词：Parkinson disease NEUROINFLAMMATION a-synuclein ginsenoside Rg1 1-methyl-4-phenyl-1 2 3 6-tetrahydropyridine

Dimethyl sulfide,a metabolite of the marine microorganism,protects SH-SY5Y cells against 6-hydroxydopamine and MPP~＋-induced apoptosis: 《中国药理学与毒理学杂志》2017年第10期1004-1004,共1页Peng-fei WU Xin-lei GUAN Han LUO Fang WANG Jian-Guo CHEN; Dimethyl sulfide(DMS)has been historically recognized as a metabolite of the marine microorganism or a disgusting component for the smell of halitosis patients.In our recent study,DMS has been identified as a cytoprot...; 关键词：dimethyl sulfide Parkinson disease methionine sulfoxidereductase A 6-HYDROXYDOPAMINE

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