PROCYANIDIN

作品数：24被引量：84H指数：6
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相关领域：医药卫生更多>>
相关作者：王敏丁丽杜连祥赵俊王建农更多>>
相关机构：天津科技大学沈阳药科大学南京大学更多>>
相关期刊：《Science Bulletin》《Bioactive Materials》《Journal of Chinese Pharmaceutical Sciences》《Journal of Animal Science and Biotechnology》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划河北省自然科学基金中国博士后科学基金更多>>
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Procyanidin C1 Modulates the Microbiome to Increase FOXO1 Signaling and Valeric Acid Levels to Protect the Mucosal Barrier in Inflammatory Bowel Disease
《Engineering》2024年第11期108-120,共13页Xifan Wang Pengjie Wang Yixuan Li Huiyuan Guo Ran Wang Siyuan Liu Ju Qiu Xiaoyu Wang Yanling Hao Yunyi Zhao Haiping Liao Zhongju Zou Josephine Thinwa Rong Liu 
supported by the 111 projects of the Education Ministry of China(B18053);the National Natural Science Foundation(32130081);the National Key Research and Development Program of China(2022YFF0710402);the Pinduoduo-China Agricultural University Research Fund(PC2023B01014).
Inflammatory bowel disease(IBD)refers to a pair of prevalent conditions(Crohn’s disease and ulcerative colitis)distinguished by persistent inflammation of the large intestine.Procyanidin C1(PCC1)is a natu-rally occur...
关键词：Inflammatory bowel disease Mucosal Barrier AUTOPHAGY 
Procyanidin A_1 and its digestive products alleviate acrylamide-induced IPEC-J2 cell damage through regulating Keap1/Nrf2 pathway
《Food Science and Human Wellness》2024年第3期1475-1484,共10页Fangfang Yan Qun Lu Chengming Wang Rui Liu 
supported by the project from National Natural Science Foundation of China (31671962);Fundamental Research Funds for the Central Universities (2662019PY034)。
Our previous study has revealed that procyanidin A_(1)(A_(1))and its simulated digestive product(D-A,)can alleviate acrylamide(ACR)-induced intestine cell damage.However,the underlying mechanism remains unknown.In thi...
关键词：Procyanidin A_1 Digestive products Acrylamide Nuclear factor erythroid 2-related factor 2(Nrf2) Intestinal cell damage 
Inhibitory effect of procyanidin B2 and tannin acid on cholesterol esterase and their synergistic effect with orlistat被引量：2
《Food Science and Human Wellness》2024年第1期360-369,共10页Xiangxin Li Yijing Pu Haitao Jiang Wenxiao Jiao Wenjun Peng Wenli Tian Weibo Jiang Xiaoming Fang 
supported by the National Basic Research Program of China(‘973’program,2013CB127106)。
This study was aimed to analyze the effect of procyanidin B2(PC)and tannin acid(TA)on the activities of cholesterol esterase(CEase)and the inhibitory mechanisms of enzymatic activity.The interaction mechanisms were in...
关键词：Cholesterol esterase POLYPHENOLS Interaction mechanisms Molecular dynamic simulation Synergistic effect 
Layer-by-layer assembly of procyanidin and collagen promotes mesenchymal stem cell proliferation and osteogenic differentiation in vitro and in vivo被引量：3
《Regenerative Biomaterials》2023年第1期333-343,共11页Zhibiao Bai Kai Hu Zeyu Shou Jiahuan Yu Hongming Meng Han Zhou Liangyan Chen Tiantian Yu Ruofei Lu Na Li Chun Chen 
supported by the National Key Research&Development Program of China(2019YFE0113600);the National Natural Science Foundation of China(NSFC 81971734,32071323,32271410);the Science and Technology Projects in Fujian Province(2022FX1,2023Y4008);the Program for Innovative Research Team in Science,Scientific Research Funds of Huaqiao University(21BS113)is gratefully acknowledged。
Collagen,commonly used in tissue engineering,is widespread in various tissues.During bone tissue regeneration,collagen can stimulate the cellular response and determine the fate of cells.In this work,we integrated col...
关键词：bone marrow mesenchymal stem cells OSTEOGENESIS COLLAGEN procyanidine coating 
Antioxidant procyanidin B2 protects oocytes against cryoinjuries via mitochondria regulated cortical tension被引量：1
《Journal of Animal Science and Biotechnology》2023年第1期166-187,共22页Qingrui Zhuan Jun Li Xingzhu Du Luyao Zhang Lin Meng Yuwen Luo Dan Zhou Hongyu Liu Pengcheng Wan Yunpeng Hou Xiangwei Fu 
National Key Research and Development Program Topics,Grant/Award Number:2021YFD1200402;Chinese Universities Scientific Fund,Grant/Award Number:2021TC061;Natural Science Foundation of Hebei province,Grant/Award Number:H2020206254;Special Program for Training and Guiding Outstanding Young and Middle-aged Talents,Grant/Award Number:SKLSGIHP2021A01;National Natural Science Foundation of China,Grant/Award Number:81901562&31372307;Key research and development projects in Hebei province,Grant/Award Number:18226604D;Program of Young and Middle-aged Scientific and technological Innovation Leaders of the Xinjiang Production and Construction Corps,Grant/Award Number:2018CB025;Xinghuo program of the First Hospital of Hebei Medical University,Grant/Award Number:XH202005;The Central Guidance on Local Science and Technology Development Fund of Hebei Province,Grant/Award Number:226Z7713G。
Background:Irreversible cryodamage caused by oocyte vitrification limited its wild application in female fertility preservation.Antioxidants were always used to antagonist the oxidative stress caused by vitrification....
关键词：Cortical tension MEIOSIS MITOCHONDRIA OOCYTES Procyanidin B2 VITRIFICATION 
Efficient semisynthetic approach for large preparation of procyanidin C1 through degradation of grape seed polymeric procyanidins
《Journal of Polyphenols》2022年第1期32-41,共10页Qian Li Lina Zhang Danyang Wang Mengyao Zhao Baoshan Sun Shuting Zhang 
This work was financially supported by College Students Innovation and Entrepreneurship Training Program in 2021(No.202110163009).
An efficient method for producing trimeric procyanidin C1(PCC1)was developed through degradation of grape seed polymeric procyanidins(PPCs),using epicatechin(EC)as nucleophile and hydrochloric acid as catalyst.With th...
关键词：PROCYANIDINS EPICATECHIN DEGRADATION grape seed 
The protective effects of procyanidin C-1 on bisphenol A-induced testicular dysfunction in aged mice
《Food Science and Human Wellness》2022年第4期965-974,共10页Mastura Abd Malek Razif Dasiman Nor-Ashikin Mohamed Noor Khan Sofee Mohamed-Akhlak Mohd-Hafi zi Mahmud 
supported financially by Universiti Teknologi MARA grants (600-IRMI/DANA KCM 5/3/LESTARI – 224/2017), (600-IRMI/My RA 5/3/GIP-030/2017);Ministry of Higher Education (MOHE) grant (600-IRMI/RAGS 5/3 - 72/2015)。
The number and quality of sperm are decreased due to bisphenol A(BPA) exposure, an endocrine-disrupting chemical on the male reproductive system, especially in advanced paternal age(APA). Procyanidin C-1(PCY-1), an an...
关键词：APOPTOSIS Bisphenol A PROCYANIDIN Mitochondrial dynamics TESTIS 
Procyanidins-crosslinked small intestine submucosa: A bladder patch promotes smooth muscle regeneration and bladder function restoration in a rabbit model被引量：6
《Bioactive Materials》2021年第6期1827-1838,共12页Xiu-Zhen Zhang Yan-Lin Jiang Jun-Gen Hu Long-Mei Zhao Qiu-Zhu Chen Yan Liang Yi Zhang Xiong-Xin Lei Rui Wang Yi Lei Qing-Yi Zhang Jesse Li-Ling Hui-Qi Xie 
This work was supported by the National Key R&D Program of China(No.2017YFC1104702);Sichuan Science and Technology Program(No.2019JDRC0020);1.3.5 project for disciplines of excellence,West China Hospital,Sichuan University(No.ZYJC18002).
Currently the standard surgical treatment for bladder defects is augmentation cystoplasty with autologous tissues,which has many side effects.Biomaterials such as small intestine submucosa(SIS)can provide an alternati...
关键词：Bladder reconstruction Small intestinal submucosa PROCYANIDINS Bio-crosslinking Smooth muscle regeneration 
A-type procyanidin derivatives with antioxidant and much enhancedα-glucosidase inhibitor activities被引量：2
《Journal of Chinese Pharmaceutical Sciences》2021年第4期280-288,共9页Huiwen Zhang Haiyan Xu Yu Zhang Chaomei Ma 
National Natural Science Foundation of China(Grant No.81860688);College Students Innovation and Entrepreneurship Project of Inner Mongolia(Grant No.202010132013);the Scientific Research Project of introductory high-level talents in Inner Mongolia。
Procyanidins are natural compounds with good biological activity.However,due to a large number of phenolic hydroxyl groups in the structure,they have high polarity and low bioavailability.The preparation of A-type pro...
关键词：Peanut skin A-type procyanidin-acetone conjugate A-type procyanidin-cystein conjugate Inhibition onα-glucosidase 
Protective Effect of Procyanidin B2 on Acute Liver Injury Induced by Aflatoxin B1 in Rats被引量：6
《Biomedical and Environmental Sciences》2020年第4期238-247,共10页DENG Zhi Jie ZHAO Jing Fang HUANG Feng SUN Gui Li GAO Wei LU Li XIAO De Qiang 
financially supported by National Natural Science Foundation of China[No.31360383]。
Objective This study aimed to explore the protective effect of procyanidin B2(PCB2)on acute liver injury induced by aflatoxin B1(AFB1)in rats.Methods Forty Sprague Dawley rats were randomly divided into control,AFB1,A...
关键词：Procyanidin B2 Aflatoxin B1 Acute liver injury Oxidative stress INFLAMMATION 
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