supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Science,ICT and Future Planning,No.2018R1A2B6001123(to NYJ),No.2018R1D1A1B07040282(to JJ)
Hydrogen sulfide is an antioxidant molecule that has a wide range of biological effects against oxidative stress. Balanced oxidative stress is also vital for maintaining cellular function in biological system, where r...
supported by the National Natural Science Foundation of China,No.81303097,81373794
Damage to synaptic plasticity induced by neurotoxicity of amyloid-beta is regarded to be one of the pathological mechanisms of learning and memory disabilities in Alzheimer's disease patients. This study assumed that...
supported by a grant from the Guangdong Science&Technology Plan Program in China,No.2014A020212043;the a grant from the Shenzhen Science&Technology Plan Program in China,No.JCYJ20140414170821242;the a grant from Shenzhen Collaborative Innovation Plan Program in China,No.GJHZ20120614154914623;a grant from the Science&Technology Project of Shanxi Health and Family Planning Commission in China,No.201201060
Therapeutic hypothermia is the most promising non-pharmacological neuroprotective strategy against ischemic injury. However, shivering is the most common adverse reaction. Many studies have shown that dantrolene is ne...
Subarachnoid hemorrhage is frequently associated with poor prognoses. Three different hemo- dynamic phases were identified during subarachnoid hemorrhage: oligemia, hyperemia, and vasospasm. Each phase is associated ...
supported by the National Natural Science Foundation of China,No.30672696,81072801;the Natural Science Foundation of Beijing in China,No.7093129
The Chinese compound Kaixin fieyu Fang can be used to treat vascular depression; however, the underlying mechanism remains unclear. This study established a rat model of chronic cerebral ischemia-caused white matter d...
supported by the National Natural Science Foundation of China, No. 30960506, 81160524;the Natural Science Foundation of Ningxia Hui Autonomous Region, No. NZ11212;the Key Scientific Research Project of Ningxia Hui Autonomous Region Health Department, No. 2012152;the Project of Ningxia Medical University, No. XM2011017
Oxysophoridine, a new alkaloid extracted from Sophora alopecuroides L., has been shown to have a protective effect against ischemic brain damage. In this study, a focal cerebral ischemia/reperfusion injury model was e...
the Department of Pathophysiology of Hebei Medical University, China for their help
A correlation between metabolic alterations of neuroactive steroids and Alzheimer’s disease remains unknown. In the present study, amyloid beta (Aβ) 25-35 (Aβ25-35) injected into the bilateral campus CA1 region...
the Natural Science Foundation of Hubei Province,No.2009CDB130;Fundamental Research Funds for the Central Universities (HUST),No.M2009049
Propofol preconditioning has been shown to provide neuroprotection against spinal ischemia/reperfusion injury. In this study, spinal cord ischemia/repeffusion injury was induced by blocking the abdominal aorta in rabb...
Recent studies suggest that the activation of the Wnt signaling pathway improves memory function in rats.This study investigated the effects of Wnt-5a on amyloid β (Aβ)-induced cognitive impairment.Aβ25-35 was in...
the Natural Science Foundation of Hubei Province, No. 2007ABA060
Huanglian Jiedu decoction (HLJDD) has been shown to improve cerebral blood flow, and reduce lipid peroxidation damage to the brain and its energy metabolism. The present study was designed to observe the cerebroprot...