PROTECTIVE_EFFECT

作品数:629被引量:1924H指数:19
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相关作者:张晓林张祥建陈晓春王春波王跃军更多>>
相关机构:复旦大学福建医科大学北京大学河北医科大学第二医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金中国博士后科学基金更多>>
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  • 期刊=Neural Regeneration Researchx
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Protective effect of hydrogen sulfide on oxidative stress-induced neurodegenerative diseases被引量:10
《Neural Regeneration Research》2020年第2期232-241,共10页Rubaiya Tabassum Na Young Jeong Junyang Jung 
supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Science,ICT and Future Planning,No.2018R1A2B6001123(to NYJ),No.2018R1D1A1B07040282(to JJ)
Hydrogen sulfide is an antioxidant molecule that has a wide range of biological effects against oxidative stress. Balanced oxidative stress is also vital for maintaining cellular function in biological system, where r...
关键词:Alzheimer's DISEASE amyotrophic lateral SCLEROSIS antioxidant DIABETIC peripheral NEUROPATHY DNA oxidation hydrogen sulfide mitochondrial dysfunction oxidative stress Parkinson's DISEASE reactive oxygen species 
Protective effect of tetrahydroxy stilbene glucoside on learning and memory by regulating synaptic plasticity被引量:2
《Neural Regeneration Research》2016年第9期1480-1486,共7页Hong-bo Luo Yun Li Zun-jing Liu Li Cao Zhi-qiang Zhang Yong Wang Xiao-yan Zhang Zhao Liu Xiang-qun Shi 
supported by the National Natural Science Foundation of China,No.81303097,81373794
Damage to synaptic plasticity induced by neurotoxicity of amyloid-beta is regarded to be one of the pathological mechanisms of learning and memory disabilities in Alzheimer's disease patients. This study assumed that...
关键词:nerve regeneration tetrahydroxy stilbene glucoside AIzheimer's disease AMYLOID-BETA cognitive impairment learning and memory synaptic plasticity Fyn/N-methyl-D-aspartate receptor 2B signaling pathway NEUROPROTECTION neural regeneration 
Dantrolene enhances the protective effect of hypothermia on cerebral cortex neurons
《Neural Regeneration Research》2015年第8期1279-1285,共7页Sui-yi Xu Feng-yun Hu Li-jie Ren Lei Chen Zhu-qing Zhou Xie-jun Zhang Wei-ping Li 
supported by a grant from the Guangdong Science&Technology Plan Program in China,No.2014A020212043;the a grant from the Shenzhen Science&Technology Plan Program in China,No.JCYJ20140414170821242;the a grant from Shenzhen Collaborative Innovation Plan Program in China,No.GJHZ20120614154914623;a grant from the Science&Technology Project of Shanxi Health and Family Planning Commission in China,No.201201060
Therapeutic hypothermia is the most promising non-pharmacological neuroprotective strategy against ischemic injury. However, shivering is the most common adverse reaction. Many studies have shown that dantrolene is ne...
关键词:nerve regeneration ischemic stroke oxygen-glucose deprivation fluorescent probe neurons flow cytometry apoptosis calcium overload reactive oxygen neural regeneration 
Encephalic hemodynamic phases in subarachnoid hemorrhage:how to improve the protective effect in patient prognoses被引量:1
《Neural Regeneration Research》2015年第5期748-752,共5页Marcelo de Lima Oliveira Daniel Silva de Azevedo Milena Krajnyk de Azevedo Ricardo de Carvalho Nogueira Manoel Jacobsen Teixeira Edson Bor-Seng-Shu 
Subarachnoid hemorrhage is frequently associated with poor prognoses. Three different hemo- dynamic phases were identified during subarachnoid hemorrhage: oligemia, hyperemia, and vasospasm. Each phase is associated ...
关键词:hemodynamic phases cerebral subarachnoid hemorrhage metabolic crises 
Mechanism underlying the protective effect of Kaixin Jieyu Fang on vascular depression following cerebral white matter damage被引量:4
《Neural Regeneration Research》2014年第1期61-68,共8页Ying Zhang Shijing Huang Yanyun Wang Junhua Pan Jun Zheng Xianhui Zhang Yuxia Chen Duojiao Li 
supported by the National Natural Science Foundation of China,No.30672696,81072801;the Natural Science Foundation of Beijing in China,No.7093129
The Chinese compound Kaixin fieyu Fang can be used to treat vascular depression; however, the underlying mechanism remains unclear. This study established a rat model of chronic cerebral ischemia-caused white matter d...
关键词:nerve regeneration vascular depression ligation of the bilateral common carotid arteries chronic cerebral ischemia white matter damage Kaixin ]ieyu Fang powder Bcl-2 Bax NSFC grant neural regeneration 
Protective effect of oxysophoridine on cerebral ischemia/reperfusion injury in mice被引量:5
《Neural Regeneration Research》2013年第15期1349-1359,共11页Hongbo Wang Yuxiang Li Ning Jiang Xiaoping Chen Yi Zhang Kuai Zhang Tengfei Wang Yinju Hao Lin Ma Chengjun Zhao Yanrong Wang Tao Sun Jianqiang Yu 
supported by the National Natural Science Foundation of China, No. 30960506, 81160524;the Natural Science Foundation of Ningxia Hui Autonomous Region, No. NZ11212;the Key Scientific Research Project of Ningxia Hui Autonomous Region Health Department, No. 2012152;the Project of Ningxia Medical University, No. XM2011017
Oxysophoridine, a new alkaloid extracted from Sophora alopecuroides L., has been shown to have a protective effect against ischemic brain damage. In this study, a focal cerebral ischemia/reperfusion injury model was e...
关键词:neural regeneration traditional Chinese medicine brain injury OXYSOPHORIDINE ischemia/reperfusion injury oxidative stress N-methyI-D-aspartate receptor NEUROPROTECTION grants-supported paper NEUROREGENERATION 
Metabolic alteration of neuroactive steroids and protective effect of progesterone in Alzheimer's disease-like rats被引量:7
《Neural Regeneration Research》2013年第30期2800-2810,共11页Sha Liu Honghai Wu Gai Xue Xin Ma Jie Wu Yabin Qin Yanning Hou 
the Department of Pathophysiology of Hebei Medical University, China for their help
A correlation between metabolic alterations of neuroactive steroids and Alzheimer’s disease remains unknown. In the present study, amyloid beta (Aβ) 25-35 (Aβ25-35) injected into the bilateral campus CA1 region...
关键词:neural regeneration neurodegenerative disease neuroactive steroids Alzheimer's disease pro-gesterone amyloid beta COGNITION NEUROPROTECTION NEUROREGENERATION 
Protective effect of propofol preconditioning and postconditioning against ischemic spinal cord injury被引量:11
《Neural Regeneration Research》2011年第12期951-955,共5页Qijing Yu Ji Hu Jie Yang Shuzhou Yin 
the Natural Science Foundation of Hubei Province,No.2009CDB130;Fundamental Research Funds for the Central Universities (HUST),No.M2009049
Propofol preconditioning has been shown to provide neuroprotection against spinal ischemia/reperfusion injury. In this study, spinal cord ischemia/repeffusion injury was induced by blocking the abdominal aorta in rabb...
关键词:ischemia/reperfusion injury spinal cord PROPOFOL ANTIOXIDATION neural regeneration 
Protective effect of Wnt-5a against amyloid beta-induced memory impairment in rats
《Neural Regeneration Research》2011年第14期1052-1056,共5页Guili Zhang Lu Lu Yaping Ge Fang Deng Ying Zhang Jiachun Feng 
Recent studies suggest that the activation of the Wnt signaling pathway improves memory function in rats.This study investigated the effects of Wnt-5a on amyloid β (Aβ)-induced cognitive impairment.Aβ25-35 was in...
关键词:WNT-5A Alzheimer's disease N-methyI-D-aspartate receptor COGNITION amyloid β protein 
Cerebroprotective effect of Huanglian Jiedu decoction on amyloid protein precursor/presenilin-1 double transgenic mice
《Neural Regeneration Research》2011年第9期645-650,共6页Xin Qiu Guohua Chen Gui Mei Yuegu Wang Kaixin Wang Tao Wang Pei Feng 
the Natural Science Foundation of Hubei Province, No. 2007ABA060
Huanglian Jiedu decoction (HLJDD) has been shown to improve cerebral blood flow, and reduce lipid peroxidation damage to the brain and its energy metabolism. The present study was designed to observe the cerebroprot...
关键词:Huanglian Jiedu decoction amyloidprotein precursorlpresenilin-1 double transgenic mice effect HIPPOCAMPUS neural regeneration 
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