PROTECTIVE_EFFECT

作品数:629被引量:1924H指数:19
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相关作者:张晓林张祥建陈晓春王春波王跃军更多>>
相关机构:复旦大学福建医科大学北京大学河北医科大学第二医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金中国博士后科学基金更多>>
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  • 期刊=Journal of Hainan Medical Universityx
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Protective effect of camellia oil on H_(2)O_(2)-induced oxidative stress injury in H9C2 cardiomyocytes of rats
《Journal of Hainan Medical University》2024年第1期1-7,共7页YAN Qing GUO Zhen SUN Sai-nan LI Jing TAN Ji-yong LI Jing 
National Natural Science Foundation of China(No.82160597);Guangxi Natural Science Foundation Project(No.2020GXNSFAA159148)。
Objective: To explore the protective effect of camellia oil against H2O2-induced oxidative stress injury in rat H9C2 cardiomyocytes. Methods: CCK8 method was used to detect the cell survival rate of H9C2 cardiomyocyte...
关键词:Camellia oil H_(2)O_(2) H9C2 Oxidative stress Protective 
The protective effect and mechanism of rhein on diabetic cardiomyopathy by regulating Sirt1/PGC-1α pathway
《Journal of Hainan Medical University》2023年第19期8-8,共1页WANG Tian-tian WANG Wei YANG Cui-hua LU Bin 
National Natural Science Foundation Project (No.81873174)。
Objective:To explore the protective effects of rhein on cardiomyocyte injury in DCM and its possible mecha-nism.Methods:The diabetic model was induced by intraperitoneal injection with streptozotocin and high-fat diet...
关键词:RHEIN Diabetic cardiomyopathy SIRT1 PGC‐1α 
Protective effect of lycopene on Parkinson's disease cell model based on endoplasmic reticulum stress
《Journal of Hainan Medical University》2023年第14期15-21,共7页BAO Bo CHAI Xing-xing DENG Zi-liang LIU Lu-lu ZHU Shao-ping LI Li-li 
Science and Technology Program of Guangdong Province(No.2013B060300038);Scientific Research Foundation of Guangdong Medical University(No.GDMUM2019029)。
Objective:To evaluate the effect of lycopene on Parkinson's disease cell model and its possible mechanism.Methods:The SH-SY5Y cells were treated with 0.5μmol/L rotenone for 24 h to establish Parkinson's disease cell ...
关键词:LYCOPENE ROTENONE Parkinson's disease Endoplasmic reticulum stress 
Protective effect and mechanism of clemastine fumarate on acute lung injury in mice with intestinal ischemia-reperfusion
《Journal of Hainan Medical University》2022年第19期18-22,共5页LIU Yang LIU Jie-ting WANG Ying-bin 
This study was supported by Natural Science Foundation of Gansu Province(No.20JR10RA727)。
Objective:To evaluate the protective effect and mechanism of clemastine fumarate(CLE)on acute lung injury(ALI)in intestinal ischemia-reperfusion(I/R)mice.Methods:Twenty-four SPF Balb/c mice were randomly divided into ...
关键词:Clemastine fumarate Reperfusion injury INTESTINAL Acute lung injury 
Research progress of TRP channel's protective effect on myocardial ischemia-reperfusion injury
《Journal of Hainan Medical University》2022年第19期69-73,共5页XIE Feng DUAN Guang-jing QU Xin-liang ZHAO Bo JIANG Ya-ni YAN Ruo-nan ZHANG Jia-hao OU Li GAO Feng LI Min 
This study is supported by the National Natural Science Foundation of China(No.81303243);Innovation Team of Shaanxi University of Traditional Chinese Medicine(No.2019-QN02)。
Transient receptor potential(TRP)channels are a type of cation channel located on the cell membrane.TRP channels are divided into 7 subfamilies(TRPC,TRPA,TRPM,TRPV,TRPN,TRPP and TRPML)and widely expressed in myocardia...
关键词:Transient receptor channel Myocardial ischemia reperfusion INJURY Protective effects 
A systematic review and meta-analysis on the protective effect of combined TCM and western medicine on cardiotoxicity induced by anthracycline chemotherapy
《Journal of Hainan Medical University》2022年第5期48-48,共1页Can Liu Yan-Wei Xing Xin Su Xu Liu 
National Key Research and Development Program(No.2018YFC1704901)。
Objective:To systematically evaluate the therapeutic effect of TCM on cardiotoxicity induced by anthracycline chemotherapy to provide clinical guidance.Methods:China hownet database(CNKI),Chinese biomedical literature...
关键词:TCM Cardio-oncology CARDIOTOXICITY META-ANALYSIS Randomized controlled trial 
Study on the protective effect of Tadehaginoside on the damage of endothelial cell mitochondria induced by reactive nitrogen
《Journal of Hainan Medical University》2021年第24期6-10,共5页Qiao-Fan Huang Hao-Lin Wu Yi-Qian Xu Hao-Fei Fan Xing-Yue Fang Ai-Ping Wang Dao-Rui Yu Qing-Wen Meng Qi-Bing Liu 
National Natural Science Fund(No.81960663);College Students Innovation Training Program for Hainan Medical College in 2019(No.X201911810036)。
Objective:To investigate the protective effect of Tadehaginoside on vascular endothelial cell injury induced by reactive nitrogen.Methods:MTT colorimetry was used to detect the effect of Tadehaginoside on the survival...
关键词:Reactive nitrogen species MITOCHONDRIA Tadehaginoside Endothelial cells 
Protective effect and mechanism of dexmedetomidine on lung injury in diabetic mice with myocardial ischemia reperfusion
《Journal of Hainan Medical University》2021年第19期15-20,共6页Ai-Mei Li Jia-Xin Li Si-Yu Chen Jiang Wang 
Natural Science Foundation of Xinjiang Uygur Autonomous Region(No.2019D01C298)。
Objective:To evaluate the protective effect of dexmedetomidine and its mechanism on the lung after myocardial ischemia reperfusion in diabetic mice.Methods:Adult diabetic db/db mice aged 15 weeks were selected.The sha...
关键词:DEXMEDETOMIDINE SIRT1 Endoplasmic reticulum stress Lung injury 
Protective effect of astragaloside IV on cardiac hypertrophy in rats and its mechanism
《Journal of Hainan Medical University》2021年第18期1-6,共6页Ting Li Feng Jiang Rui Zhou He Huang Jian Huang Li Dai 
Scientific Research Project of Sichuan Education Department(No.14ZA0137)。
Objective:To investigate the effect of astragaloside IV on cardiac hypertrophy and its regulation on autophagy.Methods:Fifty male Sprague-Dawley rats were randomly divided into sham operation group and abdominal aorti...
关键词:Astragaloside IV Cardiac hypertrophy AUTOPHAGY Abdominal aortic coarctation 
Protective effect of Fructus Mume total flavone against SH-SY5Y cells damage induced by MPP+and its mechanism
《Journal of Hainan Medical University》2021年第7期11-15,共5页Chun-Ling Wang Xiao-Dong Wen Ning Luo Yuan-Jing Jiang Ying Jiang Zhen Zeng 
National Natural Science Foundation of China Project(No.82060888);Approved Project of Guangxi Health Department(No.Z2016220);Approved Project of Guangxi Administration of Traditional Chinese Medicine(No.GZZC2020107)。
Objective:To investigate the neuroprotective effects of Fructus Mume total flavone(FMF)against cell apoptosis and mitochondrial injury induced by 1-methyl-4-phenylpyridinium(MPP^(+))in human neuroblastoma(SH-SY5Y)cell...
关键词:Parkinson’s disease Fructus Mume total flavone 1-METHYL-4-PHENYLPYRIDINIUM SH-SY5Y cell Cell apoptosis 
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