PROTEIN

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Defining A Global Map of Functional Group-based 3D Ligand-binding Motifs
《Genomics, Proteomics & Bioinformatics》2022年第4期765-779,共15页Liu Yang Wei He Yuehui Yun Yongxiang Gao Zhongliang Zhu Maikun Teng Zhi Liang Liwen Niu 
supported by the National Natural Science Foundation of China(Grant No.31621002);the Ministry of Science and Technology of China(Grant No.2017YFA0504903 to LN);the Hefei National Science Center Pilot Project Funds,China(in part)。
Uncovering conserved 3D protein–ligand binding patterns on the basis of functional groups(FGs)shared by a variety of small molecules can greatly expand our knowledge of protein–ligand interactions.Despite that conse...
关键词：Protein–ligand interaction Functional group Binding motif Computational method Drug design 
Structural insights reveal the specific recognition of meiRNA by the Mei2 protein被引量：1
《Journal of Molecular Cell Biology》2022年第5期27-42,共16页Siyuan Shen Yanze jian Zhaokui Cai Fudong Li Mengqi Lv Yongrui Liu Jihui Wu Chuanhai Fu Yunyu Shi 
This work was financially supported by grants from the Ministry of Science and Technology of China(2019YFA0508403);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB39010300);the National Natural Science Foundation of China(32090040,31870760,32171222,92149302,U1932122,and 32100958);the China Postdoctoral Science Foundation(2019M662182);the Fundamental Research Funds for the Central Universities(WK2340000097).
In the fission yeast Schizosaccharomyces pombe,Mei2,an RNA-binding protein essential for entry into meiosis,regulates meiosis initiation.Mei2 binds to a specific non-coding RNA species,meiRNA,and accumulates at the sm...
关键词：Mei2 meiRNA MEIOSIS RNA-binding protein CRYSTALLOGRAPHY 
Evaluation of Thellungiella halophila ST7 for improving salt tolerance in cotton
《Journal of Cotton Research》2022年第1期1-11,共11页ALI Mohsin NAZISH Tahmina JAVAID Ayesha ZHU Yonghong LI Jing ZHANG Huangyang WU Jie XIANG Chengbin WU Shenjie ALFATIH Alamin 
supported by grants from Ministry of Science and Technology of China(Grant No.2016ZX08005004-003).
Background: Gossypium hirsutum(upland cotton) is one of the principal fiber crops in the world. Cotton yield is highly affected by abiotic stresses, among which salt stress is considered as a major problem around the ...
关键词：Gossypium hirsutum Aluminum-induced protein SALINITY Thellungiella halophila ST7 Salt tolerance 
Lateral transfer of mRNA and protein by migrasomes modifies the recipient cells被引量：13
《Cell Research》2021年第2期237-240,共4页Mingli Zhu Qin Zou Rongyao Huang Ying Li Xudong Xing Jianhuo Fang Liang Ma Lifei Li Xuerui Yang Li Yu 
the Ministry of Science and Technology of China(2016YFA0500202 and 2017YFA0503404 to L.Y.and 2016YFC0906001 to X.Y.);the National Natural Science Foundation of China(31430053,31621063 and 31561143002 to L.Y.and 81972912 to X.Y.);the Independent Research of Tsinghua University(20161080135 to L.Y.and 2019Z06QCX01 to X.Y.).
Dear Editor,Migrasomes are recently discovered vesicular organelles which form on the retraction fibers(RFs)of migrating cells.'Once detached from cells,migrasomes can rupture and release their luminal contents'in a p...
关键词：RELEASING TRANSFER RUPTURE 
Elevated methionine content in soybean seed by overexpressing maizeβ-zein protein被引量：1
《Oil Crop Science》2020年第1期11-16,共6页Chen Guo Xiujie Liu Li Chen Yupeng Cai Weiwei Yao Shan Yuan Cunxiang Wu Tianfu Han Shi Sun Wensheng Hou 
supported by the Ministry of Science and Technology of China(2016YFD0100504);National Natural Science Foundation of China(31471571);Major Science and Technology Projects of China(2016ZX08004-003,2016ZX08010-004);CAAS(Chinese Academy of Agriculture Sciences)Agricultural Science and Technology Innovation Project。
Soybean provides superior and readily available protein for human and livestock.However,nutritional value of soybean is limited due to the deficiency of an essential amino acid,methionine.To improve total methionine c...
关键词：SOYBEAN PROTEIN METHIONINE β-Zein NUTRITION 
Identification and characterization of BoPUB3: a novel interaction protein with S-locus receptor kinase in Brassica oleracea L.被引量：2
《Acta Biochimica et Biophysica Sinica》2019年第7期723-733,共11页Songmei Shi Qiguo Gao Tonghong Zuo Zhenze Lei Quanming Pu Yukui Wang Guixi Liu Xinhua He Xuesong Ren Liquan Zhu 
This work was supported by the grants from the National Natural Science Foundation of China (No.31572127);the Chongqing Natural Science Foundation (No.cstc2012jjB80010);the National Basic Research Program of China (No.2012CB113900);Chongqing Graduate Research and Innovation Project (No.CYS18085).
Armadillo repeat containing 1 (ARC1) is phosphorylated by S-locus receptor kinase (SRK) and functions as a positive regulator in self-incompatibility response of Brassica. However, ARC1 only causes partial breakdown o...
关键词：expression ANALYSIS gene cloning PROTEIN INTERACTION S-LOCUS receptor kinase SUBCELLULAR localization SYNTENY ANALYSIS 
Control of grain size by G protein signaling in rice被引量：7
《Journal of Integrative Plant Biology》2019年第5期533-540,共8页Ran Xu Na Li Yunhai Li 
supported by the grants from the Ministry of Agriculture of China (2016ZX08009003-003);the National Basic Research Program of China (2016YFD0100501);the National Natural Science Foundation of China (31871219, 31771340 and 31400249)
Heterotrimeric G proteins are involved in multiple cellular processes in eukaryotes by sensing and transducing various signals. G protein signaling in plants is quite different from that in animals, and the mechanisms...
关键词：Heterotrimeric G PROTEINS CELLULAR processes in EUKARYOTES G PROTEIN SIGNALING 
Recent Progress on Functional Genomics Research of Enterovirus 71被引量：17
《Virologica Sinica》2019年第1期9-21,共13页Huiqiang Wang Yuhuan Li 
supported by the National Natural Science Foundation of China (Grant 81503118);CAMS Initiative for Innovative Medicine (CAMS-I2 M-1-010);The National Science and Technology Major Project of the Ministry of Science and Technology of China (2018ZX09711003-005-004)
Enterovirus 71(EV71) is one of the main pathogens that causes hand-foot-and-mouth disease(HFMD). HFMD caused by EV71 infection is mostly self-limited; however, some infections can cause severe neurological diseases, s...
关键词：ENTEROVIRUS 71 (EV71) FUNCTIONAL GENOMICS Structural PROTEIN Nonstructural PROTEIN VIRAL PROTEIN function 
Comparative analysis of protein kinases and associated domains between Ascomycota and Basidiomycota
《Journal of Integrative Agriculture》2019年第1期96-107,共12页PEI Guo-liang GUO Jun WANG Qin-hu KANG Zhen-sheng 
supported by the National Science & Technology Pillar Program of China during the Twelfth Five-Year Plan period (2012BAD19B04);the National Natural Science Foundation of China (31371924);the 111 Project from the Ministry of Education of China (B07049);the National Basic Research Program of China (2013CB127700)
Protein kinases play an important role in every aspect of cellular life.In this study,we systemically identified protein kinases from the predicted proteomes of 59 representative fungi from Ascomycota and Basidiomycot...
关键词：PROTEIN KINASES ASSOCIATED DOMAINS ASCOMYCOTA BASIDIOMYCOTA 
In situ protein micro-crystal fabrication by cryo-FIB for electron diffraction
《Biophysics Reports》2018年第6期339-347,共9页Xinmei Li Shuangbo Zhang Jianguo Zhang Fei Sun 
Micro-electron diffraction(Micro ED) is an emerging technique to use cryo-electron microscope to study the crystal structures of macromolecule from its micro-/nano-crystals, which are not suitable for conventional X-r...
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