云南高校图书馆联盟文献共享服务平台- PROTEIN

PROTEIN_EXPRESSION: 作品数：291被引量：759H指数：12; 导出分析报告; 相关作者：顾芝萍冷颖瞿秋霞张学光董琦更多>>; 相关机构：中国科学院上海生命科学研究院北京大学中国医科大学附属第一医院深圳市慢性病防治中心更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金国家教育部博士点基金更多>>

Specific dendritic spine modifications and dendritic transport:From in vitro to in vivo: 《Neural Regeneration Research》2026年第2期665-666,共2页Albert H.K.Fok Charlotte H.M.Lam Cora S.W.Lai; supported by the National Natural Science Foundation of China(NSFC/RGC/JRF N_HKU735/21);Research Grant Council of Hong Kong,China(17102120,17108821,17103922,C1024-22GF,C7074-21G);Health and Medical Research Fund(HMRF 09200966)(to CSWL);FRQS Postdoctoral Fellowship(to AHKF).; Dendritic spines are small protrusions along dendrites that contain most of the excitatory synapses in principal neurons,playing a crucial role in neuronal function by creating a compartmentalized environment for sign...; 关键词：excitatory synapses principal neuronsplaying compartmentalized environment establish maintain synapses cornejo dendritic spines regulate calcium signal dynamicsallowing regulation protein expression dendritic shaft

NOVA1 promotes SMN2 exon 7 splicing by binding the UCAC motif and increases SMN protein expression被引量：1: 《Neural Regeneration Research》2022年第11期2530-2536,共7页Li-Li Du Jun-Jie Sun Zhi-Heng Chen Yi-Xiang Shao Liu-Cheng Wu; the National Natural Science Foundation of China,No.32000841(to JJS);a grant from Science and Technology Project of Nantong of Jiangsu Province,No.JC2018090(to LCW);a grant from Graduate Research and Innovation Project of Jiangsu Province,No.KYCX18-2415(to LLD)。; Spinal muscular atrophy(SMA)is a rare hereditary neuromuscular disease with a high lethality rate in infants.Variants in the homologous genes survival of motor neuron(SMN)1 and SMN2 have been reported to be SMA pathog...; 关键词：exon 7 inclusion motor neuron neuro-oncological ventral antigen 1 SMN2 splicing spinal cord spinal muscular atrophy splicing factors UCAC motif

Neuroprotective mechanism of Kai Xin San: upregulation of hippocampal insulin-degrading enzyme protein expression and acceleration of amyloid-beta degradation被引量：12: 《Neural Regeneration Research》2017年第4期654-659,共6页Na Wang Yong-ming Jia Bo Zhang Di Xue Maharjan Reeju Yan Li Shu-ming Huang Xue-wei Liu; supported by the National Natural Science Foundation of China,No.81303248,81603321;the Natural Science Foundation of Heilongjiang Province of China,No.H2015028;a grant from the Nursing Program for Young Scholars of Heilongjiang Province of China,No.UNPYSCT-2016116;the Scientific Research Fund for Doctors of Qiqihar Medical University in China,No.QY2016B-09; Kai Xin San is a Chinese herbal formula composed of Radix Ginseng, Poria, Radix Polygalae and Acorus Tatarinowii Rhizome. It has been used in China for many years for treating amnesia. Kai Xin San ameliorates amyloid-...; 关键词：nerve regeneration NEURODEGENERATION traditional Chinese medicine Kai Xin San insulin-degrading enzyme amyloid-β Alzheimer＇sdisease Chinese herbal compound Aβ-degrading enzymes neurons Radix Ginseng Radix Polygalae Acorus Tatarinowii Rhizoma neuralregeneration

Neural stem cells over-expressing brain-derived neurotrophic factor promote neuronal survival and cytoskeletal protein expression in traumatic brain injury sites被引量：10: 《Neural Regeneration Research》2017年第3期433-439,共7页Tao Chen Yan Yu Liu-jiu Tang Li Kong Cheng-hong Zhang Hai-ying Chu Liang-wei Yin Hai-ying Ma; supported by grants from the National Natural Science Foundation of China,No.31300812 and No.31371218; Cytoskeletal proteins are involved in neuronal survival.Brain-derived neurotrophic factor can increase expression of cytoskeletal proteins during regeneration after axonal injury.However,the effect of neural stem cell...; 关键词：nerve regeneration brain-derived neurotrophic factor neural stem cells transfect differentiation traumatic brain injury CYTOSKELETON NEUROFILAMENT microtubule-associated proteins CALMODULIN Wnt/β-catenin neural regeneration

Effect of electroacupuncture on the mRNA and protein expression of Rho-A and Rho-associated kinase Ⅱ in spinal cord injury rats被引量：10: 《Neural Regeneration Research》2017年第2期276-282,共7页You-jiang Min Li-li-qiang Ding Li-hong Cheng Wei-ping Xiao Xing-wei He Hui Zhang Zhi-yun Min Jia Pei; supported by the National Natural Science Foundation of China,No.81360562; Electroacupuncture is beneficial for the recovery of spinal cord injury, but the underlying mechanism is unclear. The Rho/Rho-associated kinase（ROCK） signaling pathway regulates the actin cytoskeleton by controlling...; 关键词：nerve regeneration spinal cord injury electroacupuncture Rho/Rho-associated kinase signaling pathway monosialoganglioside motor function cytoskeleton real-time quantitative polymerase chain reaction western blot assay hybridization in situ neural regeneration

Ischemic postconditioning protects against ischemic brain injury by up-regulation of acid-sensing ion channel 2a被引量：5: 《Neural Regeneration Research》2016年第4期641-645,共5页Wang-sheng Duanmu Liu Cao Jing-yu Chen Hong-fei Ge Rong Hu Hua Feng; Ischemic postconditioning renders brain tissue tolerant to brain ischemia,thereby alleviating ischemic brain injury.However,the exact mechanism of action is still unclear.In this study,a rat model of global brain isch...; 关键词：neural regeneration brain injury ischemic brain injury acid-sensing ion channels neuroprotection ischemic postconditioning neuroprotection protein expression neuronal density ischemic tolerance molecular mechanism gene expression nerve regeneration

Salvianolate increases heat shock protein expression in a cerebral ischemia-reperfusion injury model被引量：12: 《Neural Regeneration Research》2013年第25期2327-2335,共9页Jinnan Zhang Wei Lu Qiang Lei Xi Tao Hong You Pinghui Xie; Stroke remains a worldwide health problem. Salvianolate exerts a protective effect in various mi- crocirculatory disturbance-related diseases, but studies of the mechanisms underlying its protective action have mainly...; 关键词：neural regeneration traditional Chinese medicine brain injury salvianolic acid B SALVIANOLATE heatshock protein 22 protein kinase B cerebral ischemia-reperfusion injury apoptosis NEUROPROTECTION NEUROREGENERATION

3,4-methylenedioxyamphetamine upregulates p75 neurotrophin receptor protein expression in the rat brain: 《Neural Regeneration Research》2012年第12期955-959,共5页Chaomin Wang Zugui Peng Weihong Kuang Hanyu Zheng Jiang Long Xue Wang; supported by the National Natural Science Foundation of China (MDMA Neurotoxicity and Mechanism),No.C090302; The p75 neurotrophin receptor, which is a member of the tumor necrosis factor receptor superfamil facilitates apoptosis during development and following central nervous system injury. Previous studies have shown that ...; 关键词：3 4-methylenedioxyamphetamine APOPTOSIS CYTOTOXICITY neural regeneration p75 neurotrophin receptor

Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning被引量：4: 《Neural Regeneration Research》2012年第12期896-899,共4页Yanhong Luo Yaodong Wei Taizhong Wang Dongzhu Chen Tiansheng Lu Ruibo Wu Keke Si; supported by the Guangxi Bureau of Traditional Chinese Medicine,No.[2009]73;the Department of Science and Technology,Guangxi Zhuang Autonomous Region,No.0640203; Previous studies have demonstrated that pine pollen can inhibit cerebral cortical cell apoptosis in mice with arsenic poisoning. The present study sought to detect the influence of pine pollen on apoptosis-related pro...; 关键词：pine pollen arsenic poisoning APOPTOSIS cerebral cortex neural regeneration

Apoptosis-related protein expression in rabbits with blast brain injury following early hyperbaric oxygen therapy被引量：1: 《Neural Regeneration Research》2012年第17期1318-1324,共7页Shaonian Xu Jiachuan Liu Yongming Zhang Chunlin Wang Jinbiao Wang Yanyan Yang Jian Huo Wenjiang Sun; supported by the Eleventh-Five Major Subject of Nanjing Military Area Command (Functional MRI of HBOT for acute severe traumatic brain injury),No.06Z19;the Military Medical Science and Technology Innovation Foundation in 2009 (Clinical study of CTP and NRS in traumatic SAH patients),No. 09Z009; We treated detonator-explosion-induced craniocerebral injury in rabbits with hyperbaric oxygen 1 24 hours post-injury. Expression of the apoptosis-regulating protein cytochrome c, the pro-apoptotic protein Bax and the...; 关键词：hyperbaric oxygen craniocerebral injury CASPASE-3 cytochrome c BAX Bcl-2 neural regeneration

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