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SKELETAL_MUSCLE: 作品数：348被引量：778H指数：13; 导出分析报告; 相关作者：陈帅傅力牛燕媚袁海瑞李庆云更多>>; 相关机构：南京大学天津医科大学陕西师范大学浙江大学医学院附属邵逸夫医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金湖北省自然科学基金更多>>

Metabolome and RNA-seq reveal discrepant metabolism and secretory metabolism profile in skeletal muscle between obese and lean pigs at different ages: 《Science China(Life Sciences)》2025年第4期1102-1117,共16页Liu Guo Junfei Xu Wenyue Zhou Sisi Chen Hanjing Shi Mengmeng Han Zekun Yang Yehui Duan Weijun Pang Yulong Yin Fengna Li; supported by the National Natural Science Foundation of China(31972582);the STI 2030-Major Project(2023ZD04072);the Major Project of Changsha City(kh2401015);the Science and Technology Innovation Program of Hunan Province(2021RC4039);the Key Research and Development Program of Hunan Province(2022NK2026);the Youth Innovation Promotion Association CAS(Y202079);China Agriculture Research System of MOF and MARA(CARS-35)。; Metabolites and metabolism-related gene expression profiles in skeletal muscle change dramatically under obesity,aging and metabolic disease.Since obese and lean pigs are ideal models for metabolic research.Here,we co...; 关键词：skeletal muscle METABOLOME transcriptome biomarker metabolite intercellular communication lipid deposition pig model

Unlocking the secrets of exercise:A pathway to enhanced insulin sensitivity and skeletal muscle health in type 2 diabetes: 《Journal of Sport and Health Science》2025年第2期71-74,共4页Juleen R.Zierath Aidan J.Brady Kirstin A.Macgregor Joaquin Ortiz de Zevallos Ben Stocks; supported by the Swedish Research Council(201500165);a Wallenberg Scholars Award from the Knut and Alice Wallenberg Foundation(KAW 2023.0312);The Novo Nordisk Foundation Center for Basic Metabolic Research is an independent research center at the University of Copenhagen,partially funded by an unrestricted donation from the Novo Nordisk Foundation(NNF23SA0084103).; 1.Exercise enhances muscle function and insulin sensitivity Skeletal muscle plays a fundamental role in not only locomotion,but also systemic metabolism.In people with type 2 diabetes,skeletal muscle is a major site o...; 关键词：impaired insulin signaling metabolic dysfunction muscle function type diabetes insulin sensitivity reduced glucose transport activity skeletal muscle

Muscle loss treatment by muscle-inspired shape-memory polymers Pingan Song: 《National Science Review》2025年第3期81-82,共2页Pingan Song; Volumetric muscle loss(VML)is a severe debilitating clinical issue due to the mas-sive loss of skeletal muscle that can cause critical functional disability and impair-ments[1].Current prevailing treatments encompass ...; 关键词：volumetric muscle loss volumetric muscle loss vml physical therapy skeletal muscle muscle inspired shape memory polymers TREATMENT

Muscle Rejuvenator: 《Bulletin of the Chinese Academy of Sciences》2025年第1期16-16,共1页; The“longevity protein”SIRT5 could hold the key to delaying age-related muscle decline.A study led by researchers from the Institute of Zoology(IOZ)of the Chinese Academy of Sciences and Capital Medical University in...; 关键词：longevity protein preserving muscle mass function mitigates skeletal muscle aging muscle rejuvenator pro inflammatory pathways institute zoology ioz skeletal muscle aging SIRT

Autophagy in skeletal muscle dysfunction of chronic obstructive pulmonary disease: implications, mechanisms, and perspectives: 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2025年第3期227-239,共13页Xiaoyu HAN Peijun LI Meiling JIANG Yuanyuan CAO Yingqi WANG Linhong JIANG Xiaodan LIU Weibing WU; supported by the National Natural Science Foundation of China(No.82172551);the Health Discipline Leader Project of Shanghai Municipal Health Commission(No.2022XD044),China.; Skeletal muscle dysfunction is a common extrapulmonary comorbidity of chronic obstructive pulmonary disease(COPD) and is associated with decreased quality-of-life and survival in patients. The autophagy lysosome pathw...; 关键词：AUTOPHAGY Skeletal muscle dysfunction Chronic obstructive pulmonary disease MITOCHONDRIA Muscle satellitecell

20-Hydroxyecdysone Partially Alleviates Ischemia/Reperfusion-Induced Damage of Mouse Hind Limb Skeletal Muscle: 《BIOCELL》2025年第3期437-450,共14页Alena A.Semenova Anastasia D.Igoshkina Alena A.Cherepanova Natalia V.Mikina Anastasia E.Stepanova Olga E.Krasnoshchekova Vyacheslav A.Sharapov Rimma G.Savchenko Lyudmila V.Parfenova Mikhail V.Dubinin; supported by a grant from the Russian Science Foundation(23-75-01061)。; Objectives:Skeletal muscle ischemia/reperfusion injury(IRI)occurs as a result of a marked reduction in arterial perfusion to a limb and can lead to tissue death and threaten limb viability.This work assessed the effec...; 关键词：Skeletal muscle ISCHEMIA/REPERFUSION 20-HYDROXYECDYSONE MITOCHONDRIA oxidative stress

Massive sarcomerogenesis in human skeletal muscle following long-term eccentric exercise intervention: 《Journal of Sport and Health Science》2025年第1期64-66,共3页Heiliane de Brito Fontana Walter Herzog; Sarcomerogenesis,the addition of serial sarcomeres in skeletal muscle myofibrils and fibres,is a natural occurrence during growth and maturation of animals,including humans.However,the detailed mechanisms that allow f...; 关键词：long term eccentric exercise sarcomerogenesis serial sarcomeres muscle joint function skeletal muscle myofibrils fibresis skeletal muscle

Determination of DNA content as quality control in decellularized tissues:challenges and pitfalls: 《Regenerative Biomaterials》2025年第1期170-177,共8页Charlot Philips Lisanne Terrie Ewout Muylle Lieven Thorrez; supported by the Research Foundation—Flanders[G0D3620N and 1133520N]。; Decellularized organs and tissues are emerging within the field ofregenerative medicine to meet the growing demand for organand tissue transplantation. Quality control of these acellular matrices prior to transplantat...; 关键词：DECELLULARIZATION skeletal muscle DNA quantification SPECTROPHOTOMETER

Investigating the Relationship between Age-Related Cardiac Hypertrophy, Skeletal Muscle Strength, and the FNDC5 Protein as a Potential Regulator: 《Journal of Biosciences and Medicines》2025年第2期450-464,共15页Tao Feng Ziyang Fang Yinjun Luo Xin Zhang Ying Li Shijing Ma Jinting Wei Xiaoyan Fang Biao Li Lingling Huang Jinhua Wang Suchan Liao; Background: Aging-induced cardiac hypertrophy and reduced skeletal muscle strength contribute to increased disease risk and life burden in the elderly. FNDC5 acts as a protective muscle factor in both cardiac and skel...; 关键词：AGING Heart Hypertrophy Skeletal Muscle FNDC5

A soft,ultra-tough and multifunctional artificial muscle for volumetric muscle loss treatment: 《National Science Review》2025年第2期224-237,共14页Peng-Fei Qiu Lei Qiang Weiqing Kong Fang-Zhou Wang Hong-Qin Wang Ke-Xin Hou Yihao Liu Cheng-Hui Li Pengfei Zheng; supported by the National Natural Science Foun-dation of China(22271139 and 22425106);the Fundamental Research Funds for the Central Universities(020514380294).; The escalating prevalence of skeletal muscle disorders highlights the critical need for innovative treatments for severe injuries such as volumetric muscle loss.Traditional treatments,such as autologous transplants,ar...; 关键词：volumetric muscle loss scaffolds shape-memory polymer skeletal muscle stimuli responsiveness

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