supported by the grants from the Natural Science Foundation of Jiangsu Province(,No.,BK20191219),High-Level Talent Support Program of Yangzhou University.
8-Oxoguanine(8oxoG)in DNA is a major oxidized base that poses a severe threat to genome stability.To counteract the mutagenic effect generated by 8oxoG in DNA,cells have evolved 8oxoG DNA glycosylase(OGG)that can exci...
2-ketoisovalerate ferredoxin oxidoreductase (VOR) is a key enzyme in hyperthermophiles catalyzing the coenzyme A-dependent oxidative decarboxylation of aliphatic amino acid-derived 2-keto acids. The enzyme purified un...