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作品数：166被引量：505H指数：10
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  • 期刊=Neural Regeneration Researchx
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The Rho-associated kinase inhibitors Y27632 and fasudil promote microglial migration in the spinal cord via the ERK signaling pathway被引量：6
《Neural Regeneration Research》2018年第4期677-683,共7页Pei-Cai Fu Rong-Hua Tang Zhi-Yuan Yu Min-Jie Xie Wei Wang Xiang Luo 
supported by the National Natural Science Foundation of China,No.81471200,81771341
Rho-associated kinase（ROCK） is a key regulatory protein involved in inflammatory secretion in microglia in the central nervous system.Our previous studies showed that ROCK inhibition enhances phagocytic activity in ...
关键词：nerve regeneration  spinal cord injury microglia ROCK Y27632 FASUDIL MIGRATION morphology ERK U0126 in-cell western blot assay  Transwell chambers neural regeneration 
Gender difference in the neuroprotective effect of rat bone marrow mesenchymal cells against hypoxiainduced apoptosis of retinal ganglion cells被引量：6
《Neural Regeneration Research》2016年第5期846-853,共8页Jing Yuan Jian-xiong Yu 
supported by grants from the National Natural Science Foundation of China,No.81100664;the Open Project of the State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,China,No.303060202400306;the Wuhan Science and Technology Dawn Project of China,No.2014070404010222;the Independent Research Project of Wuhan University of China,No.2042014kf0259
Bone marrow mesenchymal stem cells can reduce retinal ganglion cell death and effectively prevent vision loss. Previously, we found that during differentiation, female rhesus monkey bone marrow mesenchymal stem cells ...
关键词：nerve regeneration optic nerve injury bone marrow mesenchymal stem cells retinal ganglion cells NEUROPROTECTION hypoxic injury gender difference transwell system CO-CULTURE cell apoptosis flow cytometry caspase-3 neural regeneration 
In vitro model of the blood-brain barrier established by co-culture of primary cerebral microvascular endothelial and astrocyte cells被引量：7
《Neural Regeneration Research》2015年第12期2011-2017,共7页Yan Wang Ning Wang Biao Cai Guang-yun Wang Jing Li Xing-xing Piao 
supported by the National Natural Science Foundation of China,No.81374005,30973979;grant from the National Science and Technology Support Program during the Twelfth"Five-Year"Plan Period of China,No.2012BAI26B03
Drugs for the treatment and prevention of nervous system diseases must permeate the bloodbrain barrier to take effect.In vitro models of the blood-brain barrier are therefore important in the investigation of drug per...
关键词：nerve regeneration blood-brain barrier ASTROCYTES brain microvascular endothelial cells permeability CO-CULTURE Transwell chamber neural regeneration 
Puerarin exhibits greater distribution and longer retention time in neurons than astrocytes in a co-cultured system被引量：3
《Neural Regeneration Research》2015年第4期605-609,共5页Shu-Yong Wei Jie Tong Qiang Xue Fang-hong Shang Yan-jun Li Yang Liu Bin-bin Feng Xiao-yu Xu 
supported by the National Natural Science Foundation of China,No.31402237,81473549;the Fundamental Research Funds for Central Universities in China,No.XDJK2014C058,XDJK2014D023,XDJK2015D016;a grant from the National Key New Drug Development Project of China,No.2014ZX09304-306-04;the Fundamental and Front Research Funds of Chongqing of China,No.CSTC2014jcyj A80023;a grant from the Natural Science Foundation of Chongqing of China,No.CSTC2012jj A10012
The phytoestrogen puerarin has been shown to protect neurons and astrocytes in the brain, and is therefore an attractive drug in the treatment of Alzheimer’s disease, Parkinson’s disease and cerebral ischemia. Wheth...
关键词：nerve regeneration PUERARIN in vitro experiments CO-CULTURE NEURONS ASTROCYTES TRANSWELL neonatal rats neural regeneration 
Chemokine receptor 4 gene silencing blocks neuroblastoma metastasis in vitro被引量：4
《Neural Regeneration Research》2014年第10期1063-1067,共5页Xin Chen Yongjie Zhu Lulu Han Hongting Lu Xiwei Hao Qian Dong 
supported by the National Natural Science Foundation of China,No.81272986;the Natural Science Foundation of Shandong Province,No.ZR2011HZ002
This study investigated the effects of small interfering RNA （siRNA）-mediated silencing of chemokine receptor 4 （CXCR4） on the invasion capacity of human neuroblastoma cell line SH-SY5Y in vitro. Three siRNAs targ...
关键词：nerve regeneration chemokine receptor 4 small interfering RNA NEUROBLASTOMA inva-sion Transwell chamber LIPOSOME NSFC grant neural regeneration 
660 nm red light-enhanced bone marrow mesenchymal stem cell transplantation for hypoxic-ischemic brain damage treatment
《Neural Regeneration Research》2014年第3期236-242,共7页Xianchao Li Wensheng Hou Xiaoying Wu Wei Jiang Haiyan Chen Nong Xiao Ping Zhou 
the National Natural Science Foundation of China,No.30970758,31271060;the National Science and Technology Support Program of China,No.2011BAI14B04,2012BAI16B02;the Natural Science Foundation of Chongqing in China,No.cst-c2012jjA10103
Bone marrow mesenchymal stem cell transplantation is an effective treatment for neonatal hy- poxic-ischemic brain damage. However, the in vivo transplantation effects are poor and their survival, colonization and diff...
关键词：nerve regeneration stem cells Transwell assay red light hypoxic-ischemic brain damage bone marrow mesenchymal stem cells TRANSPLANTATION cell migration learning ability NSFC grant neural regeneration 
Neural cell injury microenvironment induces neural differentiation of human umbilical cord mesenchymal stem cells被引量：3
《Neural Regeneration Research》2012年第34期2689-2697,共9页Jin Zhou Guoping Tia Jinge Wang Xiaoguang Luo Siyang Zhang Jianping Li Li Li Bing Xu FengZhu Xia Wang Chunhong Jia Weijin Zhao Danyang Zhao Aihua Xu 
This study aimed to investigate the neural differentiation of human umbilical cord mesenchymal stem cells （hUCMSCs） under the induction of injured neural cells. After in vitro isolation and culture, passage 5 hUCMSC...
关键词：stem ceil umbilical cord mesenchymal stem cell CO-CULTURE induction DIFFERENTIATION neural cell microtubule-associated protein 2 injured cell TRANSWELL neural regeneration REGENERATION 
Neural differentiation of human placenta-derived mesenchymal stem cells following neural cell co-culture被引量：2
《Neural Regeneration Research》2011年第1期23-28,共6页Nailong Yang Hongyan Zhang Xiaojuan Sun Lili Xu 
We induced human placenta-derived mesenchymal stem cells （hPMSCs） to differentiate into neural cells by adding chemical reagents, despite the fact that toxic chemicals induce cell shrinkage or cytoskeletal formation...
关键词：human placenta-derived mesenchymal stem cells TRANSWELL CO-CULTURE DIFFERENTIATION neural cells 
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