云南高校图书馆联盟文献共享服务平台- TROGLITAZONE

TROGLITAZONE: 作品数：27被引量：61H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：彭佑铭刘伏友刘虹刘映红段绍斌更多>>; 相关机构：中南大学湘雅二医院广州军区广州总医院延边大学中国科学院更多>>; 相关期刊：《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《International Journal of Ophthalmology(English edition)》《国外新药介绍》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划吉林省教育厅基金上海市教育委员会重点学科基金更多>>

Boiogito Increases the Synthesis and Secretion of Adiponectin by Promoting Differentiation in Cultured Human Adipocytes: 《Health》2023年第12期1319-1337,共19页Yuan Gu Ailing Hu Takuji Yamaguchi Masahiro Tabuchi Yasushi Ikarashi Hiroyuki Kobayashi; Boiogito (BOT) ameliorates insulin resistance and diabetes in several animal models;however, the underlying mechanisms for these in vivo effects remain unclear. Thiazolidine derivatives, which are peroxisome prolifera...; 关键词：ADIPOCYTE ADIPONECTIN Boiogito DIFFERENTIATION TROGLITAZONE

Inhibition of mitochondrial fatty acid oxidation in drug-induced hepatic steatosis被引量：1: 《Liver Research》2019年第3期157-169,共13页Bernard Fromenty; Mitochondrial fatty acid oxidation(mtFAO)is a key metabolic pathway required for energy production in the liver,in particular during periods of fasting.One major consequence of drug-induced impairment of mtFAO is hepa...; 关键词：Drug-induced liver injury(DILI) Steatosis Mitochondria b-Oxidation Acetaminophen(APAP) TROGLITAZONE

Src与胶原同源插头蛋白(Shc)调控曲格列酮引起的PAE细胞自噬: 《微生物学报》2013年第10期1072-1079,共8页袁栋栋吴向琴陈秀玲姜学军; 国家自然科学基金面上项目(31171329)~~; 【目的】明确Src与胶原同源插头蛋白(Src homology and collagen homology,Shc)调控曲格列酮(troglitazone,TZ)引起的猪血管内皮(porcine aortic endothelial,PAE)细胞自噬的机制。【方法】我们先利用激光共聚焦显微镜、蛋白免疫杂交检...; 关键词：曲格列酮（troglitazone TZ）自噬磷酸腺苷激活蛋白激酶（AMP—activated protein KINASE AMPK） Unc51样激酶1（UNC·51-like kinase一1 Ulkl）

Skeletal muscle and whole body insulin resistance but not cardiac muscle insulin resistance could be improved by troglitazone therapy within 12 weeks in type-2 diabetes: 《Journal of Biomedical Science and Engineering》2012年第12期829-835,共7页Ikuo Yokoyama Toshiyuki Moritan Yusuke Inoue; Background: Existence of myocardial insulin resistance (IR) has been reported in type II diabetics (T2- DM) and coronary artery disease (CAD). Improvement in heart and skeletal muscle IR after thiazolidinedione’s the...; 关键词：INSULIN RESISTANCE Myocardial INSULIN RESISTANCE Glucose Metabolism Skeletal Muscle Type II DIABETES Mellitus 18F-FDG PET

Troglitazone Induced Apoptosis via PPARγ Activated POX-induced ROS Formation in HT29 Cells被引量：1: 《Biomedical and Environmental Sciences》2011年第4期391-399,共9页WANG Jing LV XiaoWen SHI JiePing HU XiaoSong DU YuGuo; supported by the National Basic Research Program (973) of China (No. 2009CB421605, No.2008CB418102);the National Natural Science Foundation of China (No.20890112, No. 21077127); Objective In order to investigate the potential mechanisms in troglitazone-induced apoptosis in HT29 cells,the effects of PPARγ and POX-induced ROS were explored.Methods [3-（4,5）-dimethylthiazol-2-yl]-2,5-diphenylt...; 关键词：TROGLITAZONE Apoptosis HT29 POX ROS formation PPARΓ Cytochrome c release

17β-Estradiol inhibition of PPARY-induced adipogenesis and adipocyte-specific gene expression被引量：4: 《Acta Pharmacologica Sinica》2011年第2期230-238,共9页Sunhyo JEONG Michung YOON; Aim： To investigate the molecular interaction of peroxisome proliferator-activated receptor y （PPARy） with 17β-estradiol （E） in the regulation of adipogenesis. Methods： Female ovariectomized （OVX） mice and di...; 关键词：PPARY ADIPOGENESIS 17Β-ESTRADIOL TROGLITAZONE coactivator recruitment ovariectomized mice 3T3-L1 cells

Troglitazone induced apoptosis of human pterygium fibroblasts through a mitochondrial-dependent pathway: 《International Journal of Ophthalmology(English edition)》2011年第2期143-146,共4页Xiao-Xi Yang, Jin-Tang Xu; National Natural Science Foundation of China (No.30872808); AIM: To study the effect of troglitazone on primary culture human pterygium fibroblast (HPF). METHODS: Cell viability loss and apoptosis were quantified by cell counting kit-8, AnnexinV-FITC/PI double staining, caspas...; 关键词：PTERYGIUM peroxisome proliferator-activated receptor γ TROGLITAZONE APOPTOSIS

Reversal of P-glycoprotein-mediated Multidrug Resistance in SGC7901/VCR Cells by PPARγ Activation by Troglitazone被引量：1: 《Journal of Huazhong University of Science and Technology(Medical Sciences)》2010年第3期326-331,共6页陈庆周洁蒋春舫陈娟; supported by grants from Natural Sciences Foundation of Hubei Province (No.2007ABA065);Science and Technology Key Project of Health Bureau of Hubei Province (No.JX1B006); Over-expression of P-glycoprotein(P-gp),an ATP-dependent drug efflux pump,represents one of the major mechanisms that contribute to multidrug resistance(MDR) in cancer cells.This study examined the effects of troglita...; 关键词：multidrug resistance peroxisome proliferator-activated receptor gamma P-GLYCOPROTEIN TROGLITAZONE SGC7901/VCR cells

PPARy agonists inhibit TGF-β-PKA signaling in glomeru Iosclerosis被引量：13: 《Acta Pharmacologica Sinica》2010年第1期43-50,共8页Rong ZOU Gang XU Xiao-cheng LIU Min HAN Jing-jing JIANG Qian HUANG Yong HE Ying YAO; This project was supported by the National Natural Science Foundation of China （No 30672227; 30571950; 30600667; 30700895; 30628029; 30770913）.; Aim： To study the probable mechanisms of the anti-glomerulosclerosis effects induced by peroxisome proliferator-activated receptor gamma （PPARy） agonists in rat intraglomerular mesangial cells （MCs）. Methods： Ce...; 关键词：PKA signal pathway GLOMERULOSCLEROSIS PPARY rat intraglomerular mesangial cells TROGLITAZONE TELMISARTAN

Troglitazone inhibits cell proliferation by attenuation of epidermal growth factor receptor signaling independent of peroxisome proliferator-activated receptor γ被引量：2: 《Cell Research》2009年第6期720-732,共13页Xiaoqi Li Xuanming Yang Youli Xu Xuejun Jiang Xin Li Fajun Nan Hong Tang; Peroxisome proliferator-activated receptors （PPAR） belong to the nuclear hormone receptor superfamily of ligand-dependent transcription factors. Recent results have shown that agonists of PPARy, such as troglitazone...; 关键词：EGFR PPARΓ TROGLITAZONE ENDOCYTOSIS growth arrest

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