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作品数：432被引量：1697H指数：20
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相关机构：重庆医科大学泗洪县人民医院山东省寄生虫病防治研究所上海中医药大学更多>>
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Acute cerebral small vessel disease:Classification,mechanism,and therapeutic implications
《Chinese Medical Journal》2024年第21期2561-2563,共3页Yuying Yan Yajun Cheng Shuai Jiang Mangmang Xu Chen Ye William Robert Kwapong Wendan Tao Shuting Zhang Joanna M.Wardlaw Ming Liu Bo Wu 
supported by grants from the National Natural Science Foundation of China(Nos.82071320,82371322,82301661,and 82271328);1·3·5 project for disciplines of excellence—Clinical Research Incubation Project,West China Hospital,Sichuan University(No.2020HXFH012);China Postdoctoral Science Foundation(Nos.2022M712249 and 2023T160447);Post-Doctor Research Project,West China Hospital,Sichuan University(No.2023HXBH007).
Cerebral small vessel disease(CSVD)is a significant cause of stroke and dementia.CSVD causes up to 30% of ischemic strokes and 80% of spontaneous intraparenchymal hemorrhages.[1]Compared with data from developed count...
关键词：CEREBRAL THERAPEUTIC ACUTE 
Molecular and therapeutic landscape of ferroptosis in skin diseases
《Chinese Medical Journal》2024年第15期1777-1789,共13页Jiayuan Le Yu Meng Ying Wang Daishi Li Furong Zeng Yixiao Xiong Xiang Chen Guangtong Deng 
supported by grants from the National Natural Science Foundation of China(Nos.82103183 to F.Z.,82102803,82272849 to G.D.);the Natural Science Foundation of Hunan Province(No.2022JJ40767 to F.Z.);the Natural Science Fund for Outstanding Youths in Hunan Province(No.2023JJ20093 to G.D.);the Huxiang Youth Talent Program(No.2023RC3072 to G.D.)
Regulated cell death(RCD)is a critical physiological process essential in maintaining skin homeostasis.Among the various forms of RCD,ferroptosis stands out due to its distinct features of iron accumulation,lipid pero...
关键词：Ferroptosis Skin diseases Regulated cell death Homeostasis MELANOMA PSORIASIS Systemic lupus erythematosus VITILIGO 
Iron metabolism and arthritis:Exploring connections and therapeutic avenues
《Chinese Medical Journal》2024年第14期1651-1662,共12页Dachun Zhuo Wenze Xiao Yulong Tang Shuai Jiang Chengchun Geng Jiangnan Xie Xiaobei Ma Qing Zhang Kunhai Tang Yuexin Yu Lu Bai Hejian Zou Jing Liu Jiucun Wang 
supported by grants from the National Natural Science Foundation of China(Nos.82030003 and 82001726);the CAMS Innovation Fund for Medical Sciences(No.2019-I2M-5-066);the Shanghai Municipal Science and Technology Major Project(No.2023SHZDZX02).
Iron is indispensable for the viablility of nearly all living organisms,and it is imperative for cells,tissues,and organisms to acquire this essential metal sufficiently and maintain its metabolic stability for surviv...
关键词：Iron metabolism ARTHRITIS Inflammation IMMUNITY Rheumatoid arthritis Psoriatic arthritis Gouty arthritis 
Recent advances in cancer-associated fibroblast:Biomarkers,signaling pathways,and therapeutic opportunities
《Chinese Medical Journal》2024年第6期638-650,共13页Donger Zhou Lei Zheng 
supported by grants from the Natural Science Foundation of Zhejiang Province,China(No.LQ15H160010);the National Science Foundation of China(No.81702382).
Anti-cancer therapies usually focus on tumor cells,but non-tumor stromal components in the tumor microenvironment also play vital roles in tumor initiation and progression,which may be the prognostic factors and poten...
关键词：Cancer-associated fibroblasts Tumor microenvironment Anti-cancer therapy Targeted therapy 
Insights into the molecular mechanisms and therapeutic implications of interleukin-6 for inflammatory bowel disease被引量：2
《Chinese Medical Journal》2023年第18期2143-2146,共4页Yizhe Tie Minhu Chen Shenghong Zhang 
National Natural Science Foundation of China(No.82270555)
Inflammatory bowel disease(IBD)is a debilitating chronic inflammatory disorder that primarily affects the digestive system,which mainly encompasses Crohn’s disease(CD)and ulcerative colitis(UC).Currently,the exact pa...
关键词：INFLAMMATORY SPITE CONCLUSION 
Involvement and therapeutic implications of airway epithelial barrier dysfunction in type 2 inflammation of asthma被引量：6
《Chinese Medical Journal》2022年第5期519-531,共13页Xiang Dong Mei Ding Jinjin Zhang Ismail Ogülür Yagiz Pat Mübeccel Akdis Yadong Gao Cezmi A.Akdis 
Type 2 inflammation is a complex immune response and primary mechanism for several common allergic diseases including allergic rhinitis,allergic asthma,atopic dermatitis,and chronic rhinosinusitis with nasal polyps.It...
关键词：Airway epithelial barrier Type 2 inflammation ASTHMA ALLERGEN Environmental pollutants 
Urinary Extracellular Vesicle： A Potential Source of Early Diagnostic and Therapeutic Biomarker in Diabetic Kidney Disease被引量：12
《Chinese Medical Journal》2018年第11期1357-1364,共8页Wei-Cheng Xu Ge Qian Ai-Qun Liu Yong-Qiang Li He-Qun Zou 
This study was supported by grants from the Guangdong Provincial Science and Technology Project （No. 2014A020212662）, the Science and Technology Planning Project of Southern Medical University （No. CX2016N018）, the Science and Technology Planning Project of Tianhe District, Guangzhou City （No. 201704KW011）, The Natural Science Foundation of Guangdong Province （2016A030313559）, and The South Wisdom Valley Innovative Research Team Program （No. CXTD-004, 2014）.
Objective： Diabetic kidney disease （DKD） has become one of the major causes of end-stage renal disease. Urinary extracellular vesicles （uEVs） contain rich biological information which could be the ideal source fo...
关键词：BIOMARKER Diabetic Kidney Disease Diagnosis Extracellular Vesicles Therapy 
Neurodegeneration in Diabetic Retinopathy： Current Concepts and Therapeutic Implications被引量：2
《Chinese Medical Journal》2016年第24期3001-3003,共3页Ning-Li Wang 
The prevalence of diabetes mellitus （DM） has increased significantly in recent decades in China. Recently, it has been reported that the estimated prevalence of DM among a representative sample of Chinese adults was...
关键词：Diabetic Retinopathy NEURODEGENERATION NEUROPROTECTION 
Role of matrix metalloproteinases in chronic wound healing： diagnostic and therapeutic implications被引量：2
《Chinese Medical Journal》2014年第8期1572-1581,共10页Ren Yanhan Gu Guosheng Yao Min Vickie R. Driver 
Matrix metalloproteinases （MMPs） are members of the family of zinc-dependent endopeptidases.
关键词：matrix metalloproteinase wound healing chronic wounds matrix metalloproteinase zinc-dependentnzymes diabetic foot ulcers 
Bronchoscopy in some tertiary grade A hospitals in China： two years＇ development被引量：1
《Chinese Medical Journal》2012年第12期2115-2119,共5页NIE Xiao-meng CAI Gang SHEN Xian YAO Xiao-peng ZHAO Li-jun HUANG Yi HAN Yi-ping BAI Chong LI Qiang 
Background Although bronchoscopy has been widely performed in China, little has been known about its current state and development. In order to investigate the clinical application of bronchoscopy and make instruction...
关键词：BRONCHOSCOPY survey clinical research diagnostic and therapeutic bronchology 
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