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DEGENERATION: 作品数：521被引量：1030H指数：13; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：施杞梁倩倩王拥军侯炜崔学军更多>>; 相关机构：上海中医药大学复旦大学青岛大学华中科技大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金广东省自然科学基金国家重点基础研究发展计划中国博士后科学基金更多>>

Knockdown of SIRT2 Rescues YARS-induced Charcot-Marie-Tooth Neuropathy in Drosophila: 《Neuroscience Bulletin》2024年第4期539-543,共5页Xuedong Li Mengrong Wang Xiang Gao Chenyu Li Chunyu Chen Yun Qi Ying Wan Wei Yu; supported by the National Natural Science Foundation of China(32370825,92249302,92049301,31821002);the Hubei Provincial Natural Science Foundation 2020CFB668.; Dear Editor,Charcot-Marie-Tooth disease,the most common inherited peripheral neuropathology,is highly heterogeneous among patients and associated with mutations in~100 different genes at an incidence of at least 1:2,5...; 关键词：Marie DEGENERATION PATHOLOGY

TREMble Before TREM2:The Mighty Microglial Receptor Conferring Neuroprotective Properties in TDP-43 Mediated Neurodegeneration: 《Neuroscience Bulletin》2023年第1期163-166,共4页William A.Mills III Ukpong B.Eyo; Microglia were long hailed as solely infammatory cells,and though they are responsible for the brain's immuneresponse,they perform a variety of neuroprotective func-tions including the clearance of cellular and toxic ...; 关键词：protective DEGENERATION Alzheimer

Microglial SIRPα Deletion Facilitates Synapse Loss in Preclinical Models of Neurodegeneration被引量：2: 《Neuroscience Bulletin》2022年第2期232-234,共3页Chongyun Wu Luodan Yang Hannah Youngblood Timon Cheng-Yi Liu Rui Duan; supported by the National Key Research and Development Program of China(2017YFB0403801);the National Natural Science Foundation of China(31971096 and 31771256);the Sigma Xi Grants in Aid of Research(GIAR)program(G03152021115804390).; Microglia,the principal immune cells in the brain,play a vital role in the development and homeostasis of the central nervous system[1,2].During early brain development,microglia-mediated synapse pruning contributes t...; 关键词：DEGENERATION HOMEOSTASIS clinical

Rejuvenating the Immune System:Insights for Anti-Neurodegeneration Strategies: 《Neuroscience Bulletin》2022年第1期107-109,共3页Jie Liu Yan-Jiang Wang; This highlight was supported by the National Natural Science Foundation of China(91749206 and 81930028).; Aging is the primary risk factor for various chronic disorders,especially neurodegeneration diseases,including Alzheimer’s disease(AD)and Parkinson’s disease(PD).It has been estimated that about one in ten individua...; 关键词：DEGENERATION IMMUNE DISEASES

Compensation for Neurodegeneration by Hippocampal Neurogenesis in Alzheimer’s Disease: Where is the way?被引量：3: 《Neuroscience Bulletin》2021年第6期885-888,共4页Jie Zheng Yawen Li; This insight article was supported by the National Natural Science Foundation of China(81901107);the China Postdoctoral Science Foundation(2018M632872).; Neurodegeneration,a defining hallmark of Alzheimer's disease(AD),features the progressive loss of neuronal structure and functions.Therapeutic approaches to AD show limited efficiency in halting the neurodegeneration ...; 关键词：DEGENERATION ALZHEIMER DRUGS

Degeneration Versus Development: Hunting-Out the D-Unit of Huntington's Disease被引量：1: 《Neuroscience Bulletin》2021年第5期757-760,共4页Shengyi Lu Boxun Lu; Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by a CAG trinucleotide repeat expansion exceeding a threshold length (>35repeats) in exon 1 of the huntingtin gene (HTT)[1]. The ag...; 关键词：HUNTINGTON EXCEEDING typically

Neural Tract Degeneration Correlates with Functional Impairment in Patients with Anoxic Brain Injury:A Tract-based Spatial Statistics Study被引量：1: 《Neuroscience Bulletin》2020年第8期932-936,共5页Ji-Yun Park Sung Ho Park Jeong-Hee Yang Han Do Lee Jiho Lee Ki-Hyun Byeon Seo Young Park Dongseok Yang; supported by the Basic Science Research Program of the National Research Foundation of Korea funded by the Ministry of Education (2013R1A1A4A01013178)。; Dear Editor,Anoxic brain injury(ABI)is a devastating event caused by cardiac arrest,chemical exposure,or trauma.Despite recent advances in medical diagnostic techniques and treatments,the survival rate after ABI is st...; 关键词：TRACT CARDIAC TREATMENT

Meningeal Lymphatic Vessels:A Drain of the Brain Involved in Neurodegeneration?被引量：2: 《Neuroscience Bulletin》2020年第5期557-560,共4页Yuan Cheng Yan-Jiang Wang; supported by the National Natural Science Foundation of China(91749206)。; Neurodegenerative diseases include several kinds of neurological disorder that are caused by the progressive death of neurons in different regions of the brain.Such diseases affect millions of people worldwide and imp...; 关键词：DEGENERATION diseases DEATH

NLRP3 Deficiency Attenuates Secondary Degeneration of Visual Cortical Neurons Following Optic Nerve Injury被引量：4: 《Neuroscience Bulletin》2020年第3期277-288,共12页Zhou Zhang Wenyi Liu Yubin Huang Linlin Luo Xiaofeng Cai Yunjia Liu Liqianyu Ai Jun Yan Sen Lin Jian Ye; the National Natural Science Foundation of China(81570840 and 81200926);the Academician-Led Science and Technological Innovation of Chongqing(cstc2017jcyj-yszxX0006);the Research Foundation of the Department of Ophthalmology in Daping Hospital,AMU(9-2543).; In the visual pathway, optic nerve(ON) injury may cause secondary degeneration of neurons in distal regions, such as the visual cortex. However, the role of the neuroinflammatory response in regulating secondary impai...; 关键词：NLRP3 VISUAL CORTEX Optic nerve injury VISUAL CORTICAL DEGENERATION

Acute Restraint Stress Augments 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Neurotoxicity via Increased Toxin Uptake into the Brain in C57BL/6 Mice: 《Neuroscience Bulletin》2018年第5期849-853,共5页Yasuhide Mitsumoto Atsushi Mori; supported by the Specific Research Foundation of Hokuriku University(250100); As an environmental risk factor, psychological stress may trigger the onset or accelerate the progression of Parkinson＇s disease （PD）. Here, we evaluated the effects of acute restraint stress on striatal dopaminerg...; 关键词：MPTP MPP＋ Mouse model Restraint stress Dopaminergic neuron DEGENERATION Dopamine transporter Dopamine

DEGENERATION