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Differentially expressed long noncoding RNAs and regulatory mechanism of LINC02407 in human gastric adenocarcinoma被引量：1
《World Journal of Gastroenterology》2019年第39期5973-5990,共18页Li-Li Zhou Yan Jiao Hong-Mei Chen Li-Hua Kang Qi Yang Jing Li Meng Guan Ge Zhu Fei-Qi Liu Shuang Wang Xue Bai Yan-Qiu Song 
Supported by the Science and Technology Department of Jilin Province,No.20160101028JC;the Special Funds of Provincial Strategic Adjustment of Economic Structure to Guide in Jilin Province,No.2014G074
BACKGROUND Long noncoding RNAs(lncRNAs)have been identified to play important roles in the development and progression of various tumors,including gastric cancer(GC).However,the molecular role of lncRNAs in GC progres...
关键词：GASTRIC cancer LONG noncoding RNAS LINC02407 Adhesion G proteincoupled receptor D1 MicroRNA-6845-5p MicroRNA-4455 
Identification of differentially expressed genes regulated by methylation in colon cancer based on bioinformatics analysis被引量：7
《World Journal of Gastroenterology》2019年第26期3392-3407,共16页Yu Liang Cheng Zhang Dong-Qiu Dai 
BACKGROUND DNA methylation, acknowledged as a key modification in the field of epigenetics, regulates gene expression at the transcriptional level. Aberrant methylation in DNA regulatory regions could upregulate oncog...
关键词：COLON CANCER Bioinformatics analysis The CANCER Genome Atlas project DNA METHYLATION Methylation-regulated DIFFERENTIALLY EXPRESSED genes Overall survival 
Integrated network analysis of transcriptomic and protein-protein interaction data in taurine-treated hepatic stellate cells被引量：6
《World Journal of Gastroenterology》2019年第9期1067-1079,共13页Xing-Qiu Liang Jian Liang Xiao-Fang Zhao Xin-Yuan Wang Xin Deng 
the National Natural Science Foundation of China,No.81360595 and No.81860790;Guangxi Natural Science Foundation Program,No.KJT13066;the Bagui Scholars Foundation Program of Guangxi;the Special-term Experts Foundation Program of Guangxi;the Project of Guangxi Young Teacher Fundamental Ability Promotion,No.2017KY0298
BACKGROUND Studies show that the antifibrotic mechanism of taurine may involve its inhibition of the activation and proliferation of hepatic stellate cells(HSCs). Since the molecular mechanism of taurine-mediated anti...
关键词：TAURINE Hepatic stellate cells DIFFERENTIALLY EXPRESSED genes Liver FIBROGENESIS TRANSCRIPTOMIC PROTEIN-PROTEIN interaction network 
Biomarker identification and trans-regulatory network analyses in esophageal adenocarcinoma and Barrett's esophagus被引量：5
《World Journal of Gastroenterology》2019年第2期233-244,共12页Jing Lv Lei Guo Ji-Han Wang Yu-Zhu Yan Jun Zhang Yang-Yang Wang Yan Yu Yun-Fei Huang He-Ping Zhao 
BACKGROUND Esophageal adenocarcinoma(EAC) is an aggressive disease with high mortality and an overall 5-year survival rate of less than 20%. Barrett's esophagus(BE) is the only known precursor of EAC, and patients wit...
关键词：ESOPHAGEAL ADENOCARCINOMA DIFFERENTIALLY EXPRESSED genes Barrett’s ESOPHAGUS Transcription factors Microarray 
Three-microRNA signature identified by bioinformatics analysis predicts prognosis of gastric cancer patients被引量：7
《World Journal of Gastroenterology》2018年第11期1206-1215,共10页Cheng Zhang Chun-dong Zhang Ming-hui Ma Dong-qiu dai 
Supported by National Natural Science Foundation of China,No.30572162;Natural Science Foundation of Liaoning Province,No.201602817
AIM To identify multiple micro RNAs(mi RNAs) for predicting the prognosis of gastric cancer(GC) patients by bioinformatics analysis.METHODS The original microarray dataset GSE93415,which included 20 GC and 20 tumor ad...
关键词：Gene functional ENRICHMENT PROGNOSIS BIOINFORMATIC analysis DIFFERENTIALLY EXPRESSED miRNAs GASTRIC cancer 
Vitamin D differentially regulates Salmonella-induced intestine epithelial autophagy and interleukin-1β expression被引量：4
《World Journal of Gastroenterology》2016年第47期10353-10363,共11页Fu-Chen Huang 
Supported by the Ministry of Science and Technology[MOST 103-2314-B-182-032(in part)];the Chang Gung Memorial Hospital,No.CMRPG8B1431,No.CMRPG8B1481 and No.CMRPG880443;the Stem Cell Research Core Laboratory (grant CLRPG8B0052) for technical support
AIM To investigate the effects of active vitamin D3 on autophagy and interleukin(IL)-1β expression in Salmonella-infected intestinal epithelial cells(IECs).METHODS Caco-2 cells, NOD2 siR NA-, Atg16L1 siR NA- or vitam...
关键词：Vitamin D Atg16L1 AUTOPHAGY Interleukin1β SALMONELLA Intestinal epithelia 
Interleukin-18 genetic polymorphisms contribute differentially to the susceptibility to Crohn's disease被引量：6
《World Journal of Gastroenterology》2015年第28期8711-8722,共12页Su-Jun Gao Li Zhang Wei Lu Lu Wang Lei Chen Zhen Zhu Hai-Hang Zhu 
AIM:To investigate the correlation between interleukin-18(IL-18) gene polymorphisms and the risk of developing Crohn's disease(CD).METHODS:The PubMed,CISCOM,CINAHL,Web of Science,EBSCO,Cochrane Library,MEDLINE,EMBASE ...
关键词：INTERLEUKIN-18 Single NUCLEOTIDE polymorphism Crohn's disease Meta-analysis 
Isolation and bioinformatics analysis of differentially methylated genomic fragments in human gastric cancer被引量：1
《World Journal of Gastroenterology》2008年第9期1333-1338,共6页Ai-Jun Liao Qi Su Xun Wang Bin Zeng Wei Shi 
The Key Project Fund of the Science and Technology Program of Hunan Province, No. 04SK1004;the Scientific Research Fund of Educational Department, Hunan Province, No. 99C195
AIM:To isolate and analyze the DNA sequences which are methylated differentially between gastric cancer and normal gastric mucosa. METHODS: The differentially methylated DNA sequences between gastric cancer and normal...
关键词：Gastric cancer DNA methylation Differentia sequences Methylation-sensitive representationa difference analysis 
Ephrin-B2 is differentially expressed in the intestinal epithelium in Crohn's disease and contributes to accelerated epithelial wound healing in vitro被引量：9
《World Journal of Gastroenterology》2005年第26期4024-4031,共8页Christian Hafner Stefanie Meyer Thomas Langmann Gerd Schmitz Frauke Bataille Ilja Hagen Bernd Becker Alexander Roesch Gerhard Rogler Michael Landthaler Thomas Vogt 
Supported by the Gennan Research Society (DFG-SFB 585/A8) and the Dr. Heinz Maurer Grant KFB 1.7
AIM:Eph receptor tyrosine kinases and their membrane bound receptor-like ligands, the ephrins, represent a bi-directional cell-cell contact signaling system that directs epithelial movements in development. The meanin...
关键词：Ephrin-B2 Crohn's disease IBD IEC-6 Wound healing Epithelial restitution 
Profiling of differentially expressed chemotactic-related genes in MCP-1 treated macrophage cell line using human cDNA arrays
《World Journal of Gastroenterology》2005年第16期2508-2512,共5页Guang-XingBian HongMiao LeiQiu Dong-MeiCao Bao-YuGuo 
AIM: To study the global gene expression of chemotactic genes in macrophage line U937 treated with human monocyte chemoattractant protein-1 (MCP-1) through the use of ExpreeChipTMO2 cDNA array. METHODS: Total RNA was ...
关键词：MCP-1 ExpreeChip^(TM)HO_2 
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