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EZH2-dependent myelination following sciatic nerve injury
《Neural Regeneration Research》2025年第8期2382-2394,共13页Hui Zhu Li Mu Xi Xu Tianyi Huang Ying Wang Siyuan Xu Yiting Wang Wencong Wang Zhiping Wang Hongkui Wang Chengbin Xue 
financially supported by the National Natural Science Foundation of China,Nos.82172104(to CX),81873767(to HZ);a grant from Jiangsu Provincial Research Hospital,Nos.YJXYY202204(to HZ),YJXYY202204-ZD04(to HZ);a grant from Jiangsu Provincial Key Medical Center;Jiangsu Provincial Medical Innovation Center,No.CXZX202212;Jiangsu Provincial Medical Key Discipline,No.ZDXK202240;the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);Technology Project of Nantong,No.MS22022008(to HZ);Postgraduate Research&Practice Innovation Program of Jiangsu Province,No.SJCX21_1457(to WW)。
Demyelination and remyelination have been major focal points in the study of peripheral nerve regeneration following peripheral nerve injury.Notably,the gene regulatory network of regenerated myelin differs from that ...
关键词：DEMYELINATION EZH2 MYELINATION peripheral nerve injury PRC2 REMYELINATION Schwann cells sciatic nerve crush sciatic nerve transection 
Gamma oscillations and their role in orchestrating balance and communication following stroke
《Neural Regeneration Research》2025年第2期477-478,共2页Montana Samantzis Cong Wang Matilde Balbi 
supported by the Brazil Family Program for Neurology(to MB),Alastair Rushworth Research Fund(to MS),Australian Government Research Training Program Scholarship(to MS),the National Natural Science Foundation of China(82202787)(to CW).
Induced brain oscillations in the gamma range have recently garnered attention due to their reported neuroprotective effects in the treatment of Alzheimer’s disease.This method differs from pharmacological approaches...
关键词：protective SPECIFICITY ALZHEIMER 
Modulation of p75 neurotrophin receptor mitigates brain damage following ischemic stroke in mice被引量：1
《Neural Regeneration Research》2024年第10期2093-2094,共2页Golnoush Mirzahosseini Tauheed Ishrat 
supported by the UTHSC Bridge funding award (E073005058 Bridge Support-2022);the National Institute of Health (R01-NS09 7800 and R56 NS127924-01) to TI。
Stroke is a significant leading cause of death and disability in the United States(Tsao et al.,2022).Approximately 87% of strokes fall into the ischemic category,mainly caused by arterial blockage(Jayaraj et al.,2019)...
关键词：damage ARTERIAL DEATH P75 
Using microglia-derived extracellular vesicles to capture diversity of microglial activation phenotypes following neurological injury
《Neural Regeneration Research》2024年第8期1633-1634,共2页Austyn D.Roseborough Nikita Ollen-Bittle Shawn NWhitehead 
Microglia are one of the three glial cell populations in the central nervous system(CNS),along with astrocytes and oligodendrocytes.While microglia are unique among brain cells due to their hematologic origin and perf...
关键词：NEUROLOGICAL cytes ACTIVATION 
Fibroblast growth factor 21 inhibits ferroptosis following spinal cord injury by regulating heme oxygenase-1被引量：1
《Neural Regeneration Research》2024年第7期1568-1574,共7页Qi Gu Weiping Sha Qun Huang Jin Wang Yi Zhu Tianli Xu Zhenhua Xu Qiancheng Zhu Jianfei Ge Shoujin Tian Xiaolong Lin 
supported by grants from Jiangsu Commission of Health,No.Z2021086(to XL);Science and Technology Program of Suzhou,Nos.SYSD2020008(to XL),SKYD2022012(to XL);Suzhou Municipal Health Commission,No.KJXW2020058(to XL);Science and Technology Program of Zhangjiagang,No.ZKS2018(to XL)。
Interfering with the ferroptosis pathway is a new strategy for the treatment of spinal cord injury.Fibroblast growth factor 21 can inhibit ferro ptosis and promote neurofunctional recovery,while heme oxygenase-1 is a ...
关键词：ferroptosis fibroblast growth factor 21 functional recovery heme oxygenase-1 lipid peroxidation NEURON reactive oxygen species spinal cord injury 
TDP-43 is a key molecule accelerating development of Alzheimer’s disease following traumatic brain injury
《Neural Regeneration Research》2024年第5期955-956,共2页Chu Chen 
supported by National Institutes of Health grants RF1NS076815 and R01AG058621.
Currently,more than 55 million people have dementia worldwide and Alzheimer’s disease(AD)is one of the most common causes of dementia in aging.However,no effective therapies are currently available for the prevention...
关键词：ALZHEIMER TRAUMATIC 
ATAT1 deficiency enhances microglia/macrophage-mediated erythrophagocytosis and hematoma absorption following intracerebral hemorrhage
《Neural Regeneration Research》2024年第5期1072-1077,共6页Yihua Zhang Ping Huang Min Cao Yi Chen Xinhu Zhao Xuzhi He Lunshan Xu 
supported by Science and Technology Innovation Enhancement Project of Army Medical University(to LX).
MIcroglia/macrophage-mediated erythrophagocytosis plays a crucial role in hematoma clearance after intracerebral hemorrhage.Dynamic cytoskeletal changes accompany phagocytosis.However,whether and how these changes are...
关键词：acetylatedα-tubulin α-tubulin acetyltransferase 1(ATAT1) erythrophagocytosis hematoma absorption intracerebral hemorrhage MACROPHAGE MICROGLIA 
Urolithin A alleviates blood-brain barrier disruption and attenuates neuronal apoptosis following traumatic brain injury in mice被引量：9
《Neural Regeneration Research》2022年第9期2007-2013,共7页Qiu-Yuan Gong Lin Cai Yao Jing Wei Wang Dian-Xu Yang Shi-Wen Chen Heng-Li Tian 
supported by the National Natural Science Foundation of China,Nos.81974189(to HLT),81801236(to QYG and LC),82001310(to DXY).
Urolithin A(UA)is a natural metabolite produced from polyphenolics in foods such as pomegranates,berries,and nuts.UA is neuroprotective against Parkinson’s disease,Alzheimer’s disease,and cerebral hemorrhage.However...
关键词：AUTOPHAGY blood-brain barrier cerebral edema controlled cortical impact model neuronal apoptosis NEUROPHARMACOLOGY NEUROPROTECTION tight junction protein traumatic brain injury urolithin A 
High mobility group box protein 1 and white matter injury following traumatic brain injury: perspectives on mechanisms and therapeutic strategies被引量：2
《Neural Regeneration Research》2022年第8期1739-1740,共2页Ronak Ved Susruta Manivannan Imogen Tasker Malik Zaben 
Traumatic brain injury(TBI)is a major cause of morbidity and mortality worldwide.Despite significant medical advances over recent decades,many survivors of TBI develop long term neuro-cognitive deficits.Previously,onl...
关键词：INJURIES INJURY consequences 
Corneal neuromediator profiles following laser refractive surgery被引量：9
《Neural Regeneration Research》2021年第11期2177-2183,共7页Lily Wei Yun Yang Jodhbir S.Mehta Yu-Chi Liu 
Laser refractive surgery is one of the most commonly performed procedures worldwide.In laser refractive surgery,Femtosecond Laser in Situ Keratomileusis and Refractive Lenticule Extraction have emerged as promising al...
关键词：CORNEA corneal nerves dry eye femtosecond laser laser in situ keratomileusis neuromediator refractive surgery small incision lenticule extraction 
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